Pivalopril
Based on 1 publication(s) in Google Scholar
Pivalopril is a new orally active angiotensin converting enzyme (ACE) inhibitor.
For research use only. We do not sell to patients.
- Purity: 99.54%
- CAS No.: 81045-50-3
- Formula: C16H27NO4S
- Molecular Weight:329.45
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) Pivalopril
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Biological Activity
ACE[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 81045-50-3
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Appearance Solid
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Molecular Weight 329.45
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Formula C16H27NO4S
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Color White to off-white
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SMILES
O=C(O)CN(C1CCCC1)C([C@H](C)CSC(C(C)(C)C)=O)=O
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Synonyms
Pivopril; RHC 3659(S)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Biochem Biophys Res Commun
Pivalopril improves anti-cancer efficiency of cDDP in breast cancer through inhibiting proliferation, angiogenesis and metastasis. [Abstract]2020 Dec 17;533(4):853-860. PMID: 33008601
Solvent & Solubility
DMSO : 90 mg/mL (273.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Burnier M, et al. RHC 3659: a new orally active angiotensin converting enzyme inhibitor in normal volunteers. Br J Clin Pharmacol. 1981 Dec;12(6):893-9. [Content Brief]
[2]. Wolf PS, et al. Angiotensin-converting enzyme inhibitory and antihypertensive activities of pivalopril (RHC 3659-(S)). Fed Proc. 1984 Apr;43(5):1322-5. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0354 mL | 15.1768 mL | 30.3536 mL | 75.8840 mL |
| 5 mM | 0.6071 mL | 3.0354 mL | 6.0707 mL | 15.1768 mL | |
| 10 mM | 0.3035 mL | 1.5177 mL | 3.0354 mL | 7.5884 mL | |
| 15 mM | 0.2024 mL | 1.0118 mL | 2.0236 mL | 5.0589 mL | |
| 20 mM | 0.1518 mL | 0.7588 mL | 1.5177 mL | 3.7942 mL | |
| 25 mM | 0.1214 mL | 0.6071 mL | 1.2141 mL | 3.0354 mL | |
| 30 mM | 0.1012 mL | 0.5059 mL | 1.0118 mL | 2.5295 mL | |
| 40 mM | 0.0759 mL | 0.3794 mL | 0.7588 mL | 1.8971 mL | |
| 50 mM | 0.0607 mL | 0.3035 mL | 0.6071 mL | 1.5177 mL | |
| 60 mM | 0.0506 mL | 0.2529 mL | 0.5059 mL | 1.2647 mL | |
| 80 mM | 0.0379 mL | 0.1897 mL | 0.3794 mL | 0.9486 mL | |
| 100 mM | 0.0304 mL | 0.1518 mL | 0.3035 mL | 0.7588 mL |