2. Endocrinology

Endocrinology (内分泌学)

Endocrinology

関連製品

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Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

製品番号 製品名 CAS 番号 純度 構造式
  • HY-120301
    L-366682 127819-96-9 98%
    L-366682, a cyclic hexapeptide, possesses antagonism of oxytocin.
    L-366682
  • HY-120398
    CH5447240 1253919-92-4 98%
    CH5447240 is an agonist for parathyroid hormone receptor 1 (PTHR1), that inhibits human PTHR1 with an EC50 of 12 μM. CH5447240 exhibits good metabolic stability in human liver microsomes. CH5447240 increases serum calcium levels in rats. CH5447240 can be used in research about hypoparathyroidism.
    CH5447240
  • HY-120665
    Prostaglandin B1 13345-51-2 99.32%
    Prostaglandin B1 (PGB1) is a metabolite of Prostaglandin E1 (HY-B0131). Prostaglandin E1 is a prostanoid receptor ligand.
    Prostaglandin B1
  • HY-120703
    RU 58642 143782-63-2 98%
    RU 58642 is an orally active non-steroidal antiandrogen, which displays a strong and selective affinity for androgen receptor.
    RU 58642
  • HY-120973
    Butaprost free acid 215168-33-5 98%
    Butaprost free acid is a selective prostaglandin E receptor (EP2) agonist with an EC50 of 33 nM and a Ki of 2.4 μM for murine EP2 receptor. Butaprost free acid is less activity against murine EP1, EP3 and EP4 receptors. Butaprost free acid attenuates fibrosis by hampering TGF-β/Smad2 signalling.
    Butaprost free acid
  • HY-121012
    (rac)-AG-205 442656-02-2 98%
    (rac)-AG-205 is a potent inhibitor of progesterone receptor membrane component 1 (Pgrmc1) that induces genes involved in sterol synthesis, including the INSIG1 protein, which forms a complex with PGRMC1. (rac)-AG-205 prevents neuronal resistance to hypoxic ischaemia by blocking NF-kB signalling and activation of the BDNF/PI3K/AKT pathway.
    (rac)-AG-205
  • HY-121062
    Betamethasone acibutate 5534-05-4 98%
    Betamethasone acibutate, derives from Betamethasone, is an acetate ester. Betamethasone acibutate is a glucocorticoid.
    Betamethasone acibutate
  • HY-121131
    Deacylcortivazol 4906-84-7 98%
    Deacylcortivazol, a potent glucocorticoid, is a glucocorticoid receptor (GR) activator.
    Deacylcortivazol
  • HY-121202
    Leucopterin 492-11-5 98%
    Leucopterin is the white pigment found in butterfly wings such as Brassica rapa.
    Leucopterin
  • HY-121313
    Embusartan 156001-18-2 98%
    Embusartan (BAY 10-6734) is a brain-penetrant and effective AT1 receptor blocker. Embusartan inhibits Ang II binding to brain AT1 receptors in the nuclei of central nervous system (CNS) inside due to high lipophilic character. Embusartan is promising for research of sympathetic hyperactivity and hypertension.
    Embusartan
  • HY-121565
    SaRI 59-801 80565-58-8 98%
    SaRI 59-801 is an orally effective hypoglycemic compound with stimulation activity of insulin secretion. SaRI 59-801 decreases blood glucose in several species and to elevate plasma insulin in rats and mice.
    SaRI 59-801
  • HY-121843
    Ronactolol 90895-85-5 98%
    Ronactolol, an aminopropanol derivative with β-adrenoceptor blocking activity.
    Ronactolol
  • HY-122359
    Levormeloxifene 78994-23-7 98%
    Levormeloxifene (L-Centchroman) is a selective estrogen receptor modulator (SERM), which prevents and ameliorates postmenopausal osteoporosis. Levormeloxifene causes multiple adverse gynecological effects.
    Levormeloxifene
  • HY-122446
    Valyllysine 22677-62-9 98%
    Valyllysine (Val-Lys) is a renoprotective peptide. Valyllysine can be found in G. chorda soluble proteins following hydrolysis by thermolysin. Valyllysine effectively ameliorates pathological renal injury.
    Valyllysine
  • HY-122455
    K-102 13835-19-3 98%
    K-102 is a small molecule agent that can be used for the study of nervous system diseases, endocrinology and metabolic disease.
    K-102
  • HY-122530
    Juvocimene I 75539-64-9 98%
    Juvocimene I is a potent juvenile hormone mimic. Juvocimene I can be isolated from the essential oil of sweet basil,Ocimum basilicum L.
    Juvocimene I
  • HY-122548
    Butropium bromide 29025-14-7 98%
    Butropium bromide is a competitive mAChR antagonist. Butropium bromide blocks acetylcholine-mediated glandular secretion and muscle contraction signals, suppressing salivary gland secretion and respiratory smooth muscle spasms. Butropium bromide is promising for research of excessive salivation.
    Butropium bromide
  • HY-123095
    TS 155-2 1314486-37-7 98%
    TS 155-2 (JBIR 100), an antimicrobial agent, is a Bafilomycin analogue and an antibiotic. TS 155-2 can be isolated from a culture of Streptomyces sp. TS 155-2 inhibits V-ATPase activity. V-ATPase is correlated with an increasing number of diseases such as osteopetrosis, male infertility and renal acidosis.
    TS 155-2
  • HY-123150
    UK-447841 465528-01-2 98%
    UK-447841 is a selective NEP inhibitor. UK-447841 can be used in the research of female sexual arousal disorder.
    UK-447841
  • HY-123163
    JNJ-1250132 240805-96-3 98%
    JNJ-1250132 (RWJ-66826) is an orally active and potent steroidal progesterone receptor (PR) antagonist, with an IC50 of 1.3 nM. JNJ-1250132 inhibits binding of the receptor to DNA in vitro. JNJ-1250132 is a potent competitive inhibitor of binding to the human glucocorticoid receptor (GR) (IC50=0.50 nM) and the rat androgen receptor (AR) (IC50=5.6 nM), and was a weak inhibitor of binding to human Estrogen receptor (ER) (IC50 >3000 nM).
    JNJ-1250132
製品番号 製品名 / Synonyms Application Reactivity