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(rac)-AG-205

(rac)-AG-205 is a potent inhibitor of progesterone receptor membrane component 1 (Pgrmc1) that induces genes involved in sterol synthesis, including the INSIG1 protein, which forms a complex with PGRMC1. (rac)-AG-205 prevents neuronal resistance to hypoxic ischaemia by blocking NF-kB signalling and activation of the BDNF/PI3K/AKT pathway.

For research use only. We do not sell to patients.

  • CAS No.: 442656-02-2
  • Formula: C22H23ClN6OS
  • Molecular Weight:454.98
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • (rac)-AG-205 Chemical Structure
    (rac)-AG-205 Chemical Structure
CAS No.: 442656-02-2
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Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Use of MCE Products

All NF-κB Isoforms

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All Akt Isoforms

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100 mg

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  • (rac)-AG-205 Chemical Structure
    (rac)-AG-205 Chemical Structure
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  • (rac)-AG-205