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Cat. No.: HY-122359

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Levormeloxifene

(Synonyms: L-Centchroman; L-Ormeloxifene)

Levormeloxifene (L-Centchroman) is a selective estrogen receptor modulator (SERM), which prevents and ameliorates postmenopausal osteoporosis. Levormeloxifene causes multiple adverse gynecological effects.

For research use only. We do not sell to patients.

CAS No.: 78994-23-7
Formula: C₃₀H₃₅NO₃
Molecular Weight:457.60

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Levormeloxifene Chemical Structure

CAS No.: 78994-23-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All Estrogen Receptor/ERR Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
Ishikawa	EC₅₀	13 nM Compound: 4 (Levormeloxifene)	Stimulation of alkaline phosphatase activity in Ishikawa human endometrial adenocarcinoma cells Stimulation of alkaline phosphatase activity in Ishikawa human endometrial adenocarcinoma cells	[PMID: 11738564]

Chemical Information

CAS No. 78994-23-7
Molecular Weight 457.60
Formula C₃₀H₃₅NO₃
SMILES

CC1([C@H]([C@@H](C2=CC=C(C=C2O1)OC)C3=CC=C(C=C3)OCCN4CCCC4)C5=CC=CC=C5)C
Synonyms

L-Centchroman; L-Ormeloxifene
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Goldstein SR, et al., Adverse events that are associated with the selective estrogen receptor modulator levormeloxifene in an aborted phase III osteoporosis treatment study. Am J Obstet Gynecol. 2002 Sep;187(3):521-7. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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References

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Levormeloxifene

All Estrogen Receptor/ERR Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Levormeloxifene Related Classifications

HY-122359 Related Classifications