2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-NP024
    Snake poison protein 98%
    Snake poison protein is a venom protein secreted by the salivary glands of venomous snakes.
    Snake poison protein
  • HY-NP025
    E.coli Bacterial protein 98%
    E.coli Bacterial protein is a native protein that can be isolated from E.coli.
    E.coli Bacterial protein
  • HY-NP216
    PA-IIL 98%
    PA-IIL (LecB) is a lectin produced by Pseudomonas aeruginosa. PA-IIL binds to glycosylated β1-integrin, fucose-containing glycosphingolipids, fucosylated/mannosylated neutrophil glycoconjugates, and pre-formed neutrophil extracellular traps. PA-IIL disrupts host defenses: it creates favorable conditions for Pseudomonas aeruginosa infection and dissemination by modulating the bactericidal activity of neutrophils, impairing the trafficking and recruitment of immune cells, and compromising the repair capacity of epithelial barriers. PA-IIL can be used in studies related to Pseudomonas aeruginosa infection.
    PA-IIL
  • HY-P0068
    Aminocandin 227472-48-2 98%
    Aminocandin (HMR 3270) is water-soluble antifungal agent of the echinocandin class with excellent activity against Aspergillus and Candida spp..
    Aminocandin
  • HY-P0135
    Penta lysine 19431-21-1 98%
    Penta lysine is an antibacterial agent, that inhibits E. coli, A. baumannii, P. aeruginos, S. aureus, and B. subtilis, with MIC of 1.1-18 μM.
    Penta lysine
  • HY-P0137
    CEF1, Influenza Matrix Protein M1 (58-66) 141368-69-6 98%
    CEF1, Influenza Matrix Protein M1 (58-66) is an epitope derived from the matrix protein of the influenza A virus.
    CEF1, Influenza Matrix Protein M1 (58-66)
  • HY-P0162
    HCV-IN-4 2058080-25-2 98%
    HCV-IN-4 is a potent and orally active HCV NS5A inhibitor, shows great potency against GT1a, GT2b, GT3a, GT1a Y93H and GT1a L31V, with EC90s of 3 pM, 0.3 nM, 0.01 nM, 0.5 nM and 0.02 nM, respectively.
    HCV-IN-4
  • HY-P1062
    Lauryl-LF 11 832729-14-3 98%
    Lauryl-LF 11, N-terminally acylated analogue of LF11, is a peptide with antibacterial activity.
    Lauryl-LF 11
  • HY-P1063
    LF11 832729-13-2 98%
    LF11 is a peptide with antibacterial activity.
    LF11
  • HY-P1181
    Pam2CSK4 868247-72-7 98%
    Pam2CSK4 is a TLR2 agonist. Pam2CSK4 induces the expression of iNOS and NO in macrophage cell lines via TBK1 and MyD88 molecules. Pam2CSK4 activates the NF-κB and Bruton's tyrosine kinase signaling pathways in platelets, and promotes platelet-endothelial cell interactions. TLR2 activation triggered by Pam2CSK4 expands myeloid-derived suppressor cells (MDSCs) and suppresses anti-tumor immune responses in the tumor microenvironment. Pam2CSK4 acts as a Th2-polarizing adjuvant in mouse vaccine models against Leishmania major and Brugia malayi. Pam2CSK4 can be used in the research of various diseases, including thromboinflammatory diseases, sepsis, atherosclerosis, heart failure, influenza, lymphoma, melanoma, cutaneous leishmaniasis and lymphatic filariasis.
    Pam2CSK4
  • HY-P1405
    Pam3CSK4-Biotin 1429504-10-8 98%
    Pam3CSK4-Biotin is biotinylated Pam3CSK4. Pam3CSK4-Biotin is a Toll-like receptor 1/2 (TLR1/2) agonist.
    Pam3CSK4-Biotin
  • HY-P1436
    Acetyl-pepstatin 11076-29-2 98%
    Acetyl-pepstatin is a potent classical inhibitor of aspartic proteases (PRs) with XMRV PR and HIV-1 PR Ki values of 712 nM and 13 nM.
    Acetyl-pepstatin
  • HY-P1459
    Sphistin Synthetic Peptide(12-38,Fitc in N-Terminal-Fluorescently Labeled Peptide) 98%
    Sphistin Synthetic Peptide (12-38, Fitc in N-Terminal-Fluorescently Labeled Peptide) is a truncated fragments of Sphistin Synthetic Peptide that shows potent antimicrobial activity.
    Sphistin Synthetic Peptide(12-38,Fitc in N-Terminal-Fluorescently Labeled Peptide)
  • HY-P1508
    Bactenecin 116229-36-8 98%
    Bactenecin (Bactenecin, bovine) is a potent 12-aa looped antimicrobial peptide isolated from bovine neutrophils. Bactenecin inhibits the growth of bacteria and yeast, and kills the fungus Trichophyton rubrum. Bactenecin increass membrane permeability, inhibits the growth and biofilm formation of B. pseudomallei.
    Bactenecin
  • HY-P1546
    Bombinin-Like Peptide (BLP-1) 138220-00-5 98%
    Bombinin-Like Peptide (BLP-1) is an antimicrobial peptide from Bombina species.
    Bombinin-Like Peptide (BLP-1)
  • HY-P1560
    Allergen Gal d 4 (46-61), chicken 62982-31-4 98%
    Allergen Gal d 4 (46-61), chicken is a hen egg white lysozyme peptide.
    Allergen Gal d 4 (46-61), chicken
  • HY-P1566
    MPG, HIV related 395069-92-8 98%
    MPG, HIV related is 27-aa peptide, derived from both the nuclear localisation sequence of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41 and is a potent delivery agent for the generalised delivery of nucleic acids and of oligonucleotides into cultured cells.
    MPG, HIV related
  • HY-P1586
    HIV-1 Rev (34-50) 141237-50-5 98%
    HIV-1 Rev (34-50) is a 17-aa peptide derived from the Rev-responsive element (RRE)-binding domains of Rev in HIV-1, with anti-HIV-1 activity.
    HIV-1 Rev (34-50)
  • HY-P1602
    Apidaecin IB 123276-94-8 98%
    Apidaecin IB is a insect antimicrobial peptide, with minimum inhibitory concentration (MIC) values of 8 μM for E. coli (ML35, O18K1H7 and ATCC 25922).
    Apidaecin IB
  • HY-P1631
    Polyphemusin I 125139-67-5 98%
    Polyphemusin I is a natural antimicrobial peptide with excellent antimicrobial activity against Gram-negative and Gram-positive bacteria. Polyphemusin I contains 18 amino acids and is stabilized into an amphiphilic, antiparallel β-hairpin by two disulfide bridges.
    Polyphemusin I
Cat. No. Product Name / Synonyms Application Reactivity