2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-106758
    Cefuzonam sodium 82219-81-6 98%
    Cefuzonam sodium is a second-generation cephalosporin antibiotic with activity against Staphylococcus aureus, which is resistant to most third-generation cephalosporins. Cefuzonam sodium is effective for preventing infection after cesarean delivery.
    Cefuzonam sodium
  • HY-106771
    Vaneprim 84854-86-4 98%
    Vaneprim is an antibacterial agent.
    Vaneprim
  • HY-106789
    Plaunotol 64218-02-6 98%
    Plaunotol is an orally active acyclic diterpene alcohol. Plaunotol has antibacterial activity against Helicobacter pylori which causes peptic ulcer . Plaunotol inhibits tumor angiogenesis and cell proliferation. Plaunotol induces apoptosis by activation of caspase 8 and caspase 9 pathways. Plaunotol is a potential anticancer agent against colon cancer .
    Plaunotol
  • HY-106801
    Girolline 110883-46-0 98%
    Girolline (RP 49532) is a protein synthesis inhibitor and a functional modulator of eIF5A. Girolline induces ribosome stalling by interfering with the binding of eIF5A to ribosomes. Girolline also inhibits the production of IL-6 and IL-8, and induces cell cycle arrest in tumor cells. Girolline is applicable to research related to inflammatory diseases, solid tumors, leukemia and malaria.
    Girolline
  • HY-106817
    Amitivir 111393-84-1 98%
    Amitivir (LY 217896), a thiadiazole derivative, possesses broad antiviral activity against orthomyxo- and paramyxoviruses. Amitivir is effective against influenza A and B viruses.
    Amitivir
  • HY-106843
    Phospholine 124123-09-7 98%
    Phospholine is an antibiotic. The IC50 (μg/mL) of Ll 210, P388 and EL-4 cells are 3.37, 2.20 and 1.99, respectively.
    Phospholine
  • HY-106848
    Arteflene 123407-36-3 98%
    Arteflene is a synthetic structural analogue of artemisinin. Arteflene has antimalarial activity.
    Arteflene
  • HY-106866
    Bulaquine 79781-00-3 98%
    Bulaquine (CDRI 80/53) is a potent antimalarial agent which is an analogue of Primaquine (HY-12651A). Bulaquine affects multiple metabolism pathways and shows inhibition effect on Plasmodium cynomolgi infection. Bulaquine can be used for the research of malaria.
    Bulaquine
  • HY-106872
    R82913 126347-69-1 98%
    R82913 (9-Cl-TIBO) is a potent and high selective inhibitor of HIV-1 reverse transcriptase with antiviral activity on both an RNA template (negative strand synthesis) and a DNA template (positive strand synthesis). R82913 inhibits the replication of different strains of HIV-I in CEM cells with a median IC50 value of of 0.15 μM.
    R82913
  • HY-106882
    GE 2270A 134861-34-0 98%
    GE 2270A (MDL 62879) is an antibiotic. GE 2270A inhibits gram-positive bacteria and anaerobes by inhibiting protein synthesis. GE 2270A can be used for the research of infection.
    GE 2270A
  • HY-106911
    Sanfetrinem cilexetil 141646-08-4 98%
    Sanfetrinem cilexetil (GV 118819X), a prodrug of Sanfetrinem (HY-106922), is an orally active antibiotic. Sanfetrinem cilexetil shows potent efficacy against experimental murine septicemia caused by Staphylococcus aureus, Streptococcus pyogenes, and Escherichia coli and against murine respiratory infections caused by Streptococcus pneumoniae.
    Sanfetrinem cilexetil
  • HY-106918
    Tivirapine 137332-54-8 98%
    Tivirapine (R86183) is a nonnucleoside HIV-1 RT inhibitor against HIV-1-induced cytopathic effects with an EC50 value of 4 nM. Tivirapine inhibits the Yl8lC mutant of HIV-1 RT.
    Tivirapine
  • HY-106920
    Kynostatin 272 147318-81-8 98%
    Kynostatin 272 (KNI 272) is a potent HIV protease inhibitor. Kynostatin 272 inhibits the activity of the HIV protease by simulating the substrate transition state of the HIV protease, thus preventing a key step in the replication of the HIV virus. Kynostatin 272 provides an important research foundation for the development of drugs for HIV and AIDS.
    Kynostatin 272
  • HY-106925
    Cetefloxacin 141725-88-4 98%
    Cetefloxacin (E 4868) is a board-spectrum antibacterial antibiotic, MIC of 0.007-8 µg/ml. Cetefloxacin exhibits good pharmacokinetic characters in mice. Cetefloxacin exhibits protective effects against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae in mice.
    Cetefloxacin
  • HY-106942
    CGP 53437 150736-68-8 98%
    CGP 53437 is an orally active HIV-1 protease inhibitor, with a Ki of 0.2 nM. CGP 53437 delays the onset of HIV replication.
    CGP 53437
  • HY-106959
    Flurithromycin 82664-20-8 99.73%
    Flurithromycin ((8S)-8-Fluoroerythromycin A) is an orally active broad spectrum antibiotic. Flurithromycin can be used in the research of bacterial infections.
    Flurithromycin
  • HY-106997
    Icofungipen 198022-65-0 98%
    Icofungipen is an orally active antifungal agent. Icofungipen is the representative of beta amino acids, is toxic against Candida species. Icofungipen protects infected mice survival from C. albicans infection.
    Icofungipen
  • HY-106998
    DC-756 218281-25-5 98%
    DC-756 is a fluoroquinolone antibiotic. DC-756 possesses potent activity against Gram-positive and Gram-negative pathogens comparable to Trovafloxacin (HY-A0170), with MIC, against Ofloxacin (HY-B0125)-resistant strains 16-fold better than Trovafloxacin. DC-756 is well absorbed orally in rats and found to have good photostability. DC-756 can be used to study bacterial resistance.
    DC-756
  • HY-107026
    Lagociclovir valactate 1001670-19-4 98%
    Lagociclovir valactate is a prodrug of Lagociclovir (HY-14844). Lagociclovir valactate is an orally active anti-HBV agent.
    Lagociclovir valactate
  • HY-107027
    Colistin B sulfate 1338055-88-1 98%
    Polymyxin E2 sulfate is an antibiotic produced by the soil bacterium Bacillus polymyxa.
    Colistin B sulfate
Cat. No. Product Name / Synonyms Application Reactivity