2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-121745
    Phosmet oxon 3735-33-9 98%
    Phosmet oxon (Imidoxon) is a main and toxic metabolite of phosmet. Phosmet is a cholinesterase inhibitor insecticide used on pome and stone fruits.
    Phosmet oxon
  • HY-121780
    Aranorosin 117184-53-9 98%
    Aranorosin, a potent antifungal antibiotic, has been isolated from the culture filtrate and mycelium of a strain of Pseudoarachniotus roseus Kuehn.
    Aranorosin
  • HY-121782
    A 65281 111279-49-3 98%
    A 65281 is a potent DNA gyrase inhibitor with an IC50 value of 0.1 µg/mL. A 65281 induces DNA breakage mediated by calf thymus topoisomerase II. A 65281 inhibits P4 DNA unknotting with an IC50 value of 8 µg/mL.
    A 65281
  • HY-121801
    Zarilamid 84527-51-5 98%
    Zarilamid is a fungicide which is active against a broad spectrum of Oomycete fungi. Zarilamid inhibits nuclear division in germinating zoospore cysts of Phytophthora capsici. Zarilamide inhibits growth of tobacco roots and causes swelling of the root tips, destructs microtubule cytoskeleton and inhibits mitosis.
    Zarilamid
  • HY-121820
    DMJ-I-228 1374035-59-2 98%
    DMJ-I-228 is a CD4-mimetic. DMJ-I-228 binds to HIV-1 gp120 within the conserved Phe 43 cavity near the CD4-binding site, thereby blocking CD4 binding and inhibiting HIV-1 infection.
    DMJ-I-228
  • HY-121924
    L-689065 146775-25-9 98%
    Chloracetophos is a fungicide with potential to inhibit dermatophytes.
    L-689065
  • HY-121978
    Laxifloran 27973-50-8 98%
    Laxifloran exhibits both antibacterial and antifungal properties.
    Laxifloran
  • HY-122008
    ORM-3819 360794-85-0 98%
    Levonadifloxacin ((S)-(-)-Nadifloxacin; WCK 771) arginine is a broad-spectrum antistaphylococcal agent. Levonadifloxacin arginine has antimicrobial activity against methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus and reduces phagocytosis of MRSA and MSSA strains by monocytic THP-1.
    ORM-3819
  • HY-122030
    Lithooxazoline 80724-92-1 98%
    Lithooxazoline is a potent antibacterial agent.
    Lithooxazoline
  • HY-122069
    NSC177365 80261-18-3 98%
    NSC177365 (NSC 1) is a CcrM inhibitor. NSC177365 is a competitive DNA inhibitor and disrupts DNA binding. NSC177365 has antibacterial activity, with IC50s of 2.3 and 14.6 μM for C. crescentus and M. lincolnii respectively. NSC177365 reverses several neurodegenerative disorders and serve as an anticancer agent.
    NSC177365
  • HY-122070
    Tirilazad mesylate 110101-67-2 98%
    Tirilazad mesylate (U 74006F) is a nonglucocorticoid, 21-aminosteroid that inhibits lipid peroxidation. Tirilazad mesylate can attenuate brain or spinal cord injury caused by trauma, stroke, ischemia and reperfusion injury. Tirilazad mesylate has antiviral activities against nCoV. Tirilazad mesylate is neuroprotective for ischaemic stroke, can be used for subarachnoid hemorrhage research.
    Tirilazad mesylate
  • HY-122076
    A-26771B 56448-20-5 98%
    A-26771B is an antibiotic can be obtained from Penicillium turbatum. A-26771B exhibits moderate antimicrobial activity against Gram-positive bacteria, mycoplasma, and fungi. A-26771B also inhibits potassium-dependent ATPase in rat liver mitochondria.
    A-26771B
  • HY-122123
    S-6123 87508-45-0 98%
    S-6123 is a potent antimicrobial compound of the oxazolidinone series. S-6123 inhibits ribosomal protein synthesis without inhibiting DNA or RNA synthesis.
    S-6123
  • HY-122134
    SC-58272 164931-25-3 98%
    SC-58272 is a potent and selective dipeptide N-myristoyltransferase (Nmt) inhibitor with an IC50 of 56 nM for C. albicans (strain B311) Nmt. SC-58272 shows 250-fold selective for the fungal enzyme compared to human enzyme.
    SC-58272
  • HY-122139
    Desethylene Ciprofloxacin hydrochloride 528851-31-2 98%
    Desethylene Ciprofloxacin hydrochloride is a major metabolite of Ciprofloxacin (HY-B0356). Ciprofloxacin is an orally active topoisomerase IV inhibitor. Desethylene Ciprofloxacin hydrochloride has antibacterial activity.
    Desethylene Ciprofloxacin hydrochloride
  • HY-122143
    V-06-018 299927-26-7 98%
    V-06-018 is a potent LasR antagonist with an IC50 value of 5.2 µM. V-06-018 can be used as chemical probes of quorum sensing (QS) in Pseudomonas aeruginosa.
    V-06-018
  • HY-122146
    Bactobolin B 74141-68-7 98%
    Bactobolin B (Alanylbactobolin) is a chlorine-containing antibiotic with antitumor activities.
    Bactobolin B
  • HY-122191
    AK-Toxin II 85146-10-7 98%
    AK-Toxin II is a phytotoxic metabolite that can be isolated from culture broth of alternaria alternata Japanese pear pathotype. AK-Toxin II induces characteristic veinal necrosis and rapid K+ loss on susceptible pear leaves.
    AK-Toxin II
  • HY-122200
    Phenamacril 39491-78-6 99.39%
    Phenamacril (JS399-19) inhibits activity of myosin I non-competitively with an IC50 of 360 nM through suppression of the ATPase activity, exhibits therefore an antifungal efficacy towards Fusarium species.
    Phenamacril
  • HY-122204
    5M038 338962-32-6 98%
    5M038 is an inhibitor of HIV envelope-mediated fusion with potent inhibitory activity against gp41-mediated membrane fusion. 5M038 prevents the formation of the gp41 post-fusion conformation and inhibits envelope-mediated membrane fusion in cell-cell fusion and viral infectivity assays. 5M038 has shown broad fusion inhibition in tests against multiple HIV-1 subtypes, including M and T strains. 5M038 targets a highly conserved hydrophobic pocket and binds to the gp41 trimer, thereby exerting its inhibitory effect.
    5M038
Cat. No. Product Name / Synonyms Application Reactivity