SC-58272
SC-58272 is a potent and selective dipeptide N-myristoyltransferase (Nmt) inhibitor with an IC50 of 56 nM for C. albicans (strain B311) Nmt. SC-58272 shows 250-fold selective for the fungal enzyme compared to human enzyme.
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- CAS. Nr.: 164931-25-3
- Formel: C33H52N6O4
- Molecular Weight:596.80
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
SC-58272 shows IC50 values of 56 nM and 14100 nM for E. coli-derived human and C. albicans (strain B311) Nmts (HNmt and CaNmt, respectively)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 164931-25-3
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Molecular Weight 596.80
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Formel C33H52N6O4
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SMILES
O=C(NCCC1CCCCC1)[C@H](CCCCN)NC([C@H](CO)NC(CC2=CC=C(C=C2)CCCCN3C(C)=NC=C3)=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)