164931-25-3
Chemical Structure
SC-58272
- CAS No.: 164931-25-3
- Formula:C33H52N6O4
- Molecular Weight:596.80
IUPAC Name: (S)-6-amino-N-(2-cyclohexylethyl)-2-((S)-3-hydroxy-2-(2-(4-(4-(2-methyl-1H-imidazol-1-yl)butyl)phenyl)acetamido)propanamido)hexanamide
InChIKey: WHLPIOSHBKQGHA-KYJUHHDHSA-N
SMILES: O=C(NCCC1CCCCC1)[C@H](CCCCN)NC([C@H](CO)NC(CC2=CC=C(C=C2)CCCCN3C(C)=NC=C3)=O)=O
Biological Activity: SC-58272 is a potent and selective dipeptide N-myristoyltransferase (Nmt) inhibitor with an IC50 of 56 nM for C. albicans (strain B311) Nmt. SC-58272 shows 250-fold selective for the fungal enzyme compared to human enzyme[1].
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SC-58272 | SC-58272 is a potent and selective dipeptide N-myristoyltransferase (Nmt) inhibitor with an IC50 of 56 nM for C. albicans (strain B311) Nmt. SC-58272 shows 250-fold selective for the fungal enzyme compared to human enzyme. | |||||||||||||||||||||
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Keywords
