2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N16392
    14-epi-Berkeleylactone F 3085255-21-3
    14-epi-Berkeleylactone F (Compound 8) is a C-14 epimer of Berkeleylactone F (HY-N8386). 14-epi-Berkeleylactone F can be isolated from Penicillium turbatum NRRL 5630. 14-epi-Berkeleylactone F has no significant biological activity against bacterium (Staphylococcus aureus, Bacillus subtilis and E. coli), fungi Candida albicans, the parasite Giardia duodenalis and NS-1 murine myeloma cells.
    14-epi-Berkeleylactone F
  • HY-N16397
    Anhydrofulvic acid 95730-85-1
    Anhydrofulvic acid is a polyketide with antibacterial activity (notably against MRSA, MIC=8 mg/mL). Anhydrofulvic acid is promising for research of Gram-positive infections (e.g., skin, bloodstream).
    Anhydrofulvic acid
  • HY-N16398
    Arenicolin B 2757119-20-1
    Arenicolin B is a C-glycosylated depside. Arenicolin B is promising for research of cancers and infections.
    Arenicolin B
  • HY-N16400
    Aspergillumarin A 1392495-06-5
    Aspergillumarin A is a dihydroisocoumarin derivative with various biological activity. Aspergillumarin A inhibits cell proliferation by inducing G0/G1 phase arrest in HepG2 hepatocellular carcinoma cells.. Aspergillumarin A exhibits weak antibacterial activity against Staphylococcus aureus and Bacillus subtilis. Aspergillumarin A can be used for the study of hepatocellular carcinoma (HCC)
    Aspergillumarin A
  • HY-N16401
    Aspergillumarin B 1392495-07-6
    Aspergillumarin B (Compound 2) is a derivative of dihydroisocoumarin. Aspergillumarin B can be isolated from the endophytic fungus Aspergillus sp.. Aspergillumarin B has a weak antibacterial activity against Staphylococcus aureus and Bacillus subtilis.
    Aspergillumarin B
  • HY-N16407
    Austdiol 53043-28-0
    Austdiol (NSC 159632) is an azaphilone derivative with antimicrobial activity. Austdiol is promising for research of infectious diseases.
    Austdiol
  • HY-N16410
    N-cis-Dodec-5(Z)-enoyl-L-homoserine lactone 945495-73-8
    N-cis-Dodec-5(Z)-enoyl-L-homoserine lactone (5-cis-C12-HSL) (Compound 2) is an acylated homoserine lactone. N-cis-Dodec-5(Z)-enoyl-L-homoserine lactone can be isolated for Mesorhizobium sp. N-cis-Dodec-5(Z)-enoyl-L-homoserine lactone restores protease and pyoverdin production of an AHL-deficient Pseudomonas aeruginosa PAO1 lasI rhlI double mutant. N-cis-Dodec-5(Z)-enoyl-L-homoserine lactone has no significant antibacterial activity and cytotoxicity against tumor cells.
    N-cis-Dodec-5(Z)-enoyl-L-homoserine lactone
  • HY-N16417
    Elsinochrome C 24512-87-6 98%
    Elsinochrome C is a photosensitizer. Elsinochrome C relies on light activation to generate reactive oxygen species (ROS) such as singlet oxygen (1O2), inducing apoptosis or directly disrupting pathogen structures. Elsinochrome C is promising for research of skin cancers, HIV-associated infections, and refractory skin diseases.
    Elsinochrome C
  • HY-N16418
    Epanorin 18463-10-0
    Epanorin is a secondary metabolite of the Acarospora lichenic species Epanorin can inhibit cancer cells proliferation, ROS production and induce G0/G1 phase arrest. Epanorin shows antibacterial activity. Epanorin can be used for the researches of cancer and infection, such as breast cancer and S. pneumonia infection.
    Epanorin
  • HY-N16419
    Haenamindole 1818844-73-3
    Haenamindole is an alkaloid. Haenamindole is promising for research of bacterial infection and cancers.
    Haenamindole
  • HY-N16421
    Leporin A 140381-54-0 98%
    Leporin A is an insecticide. Leporin A binds to GABA receptors or sodium channels to disrupt neurotransmission.
    Leporin A
  • HY-N16422
    Mer-NF5003E 159121-98-9
    Mer-NF5003E is a non-nucleoside reverse transcriptase inhibitor targeting HIV-1 reverse transcriptase (RT) (EC50=50 μM). Mer-NF5003E exhibits inhibitory activity against wild-type HIV-1 and multiple NNRTI-resistant strains (e.g., K103N, Y181C). Mer-NF5003E is promising for research of HIV infections.
    Mer-NF5003E
  • HY-N16424
    Methyl (Z)-ferulate 34298-89-0
    Methyl (Z)-ferulate (Me cis-ferulate) (cis-Ferulic acid methyl ester) is an endogenous Germination self-inhibitor. Methyl (Z)-ferulate can be isolated from the leaves of Tetragonia tetragonoides. Methyl (Z)-ferulate blocks uredospores germination in rust fungi by reversibly inhibiting the digestion of the germination pore plug through the regulation of pre-existing enzyme activity. Methyl (Z)-ferulate also has antioxidant activity, effectively scavenging DPPH and ABTS+ radical.
    Methyl (Z)-ferulate
  • HY-N16425
    Mitorubrin 3403-71-2 98%
    Mitorubrin ((-)-Mitorubrin) is a compound that can be isolated from Penicillium purpurogenum JS03-21. Mitorubrin shows no significant inhibitory activity against the H1N1 influenza virus (IC50 > 200 μM).
    Mitorubrin
  • HY-N16426
    Mycoleptone A 1532554-02-1
    Mycoleptone A is an azafluorenone compound. Mycoleptone A exhibits certain anti-leishmanial activity, with an LD50 of 28.5 μM against L. major. Mycoleptone A shows cytotoxicity against human prostate cancer cell line PC3, with an IC50 of 10.0 μM. Mycoleptone A can be used in research on anti-parasitic and anti-tumor aspects.
    Mycoleptone A
  • HY-N16428
    Neoaspergillic acid 2152-59-2 98%
    Neoaspergillic acid (NSC 356436) (Compound 2) is a microbial secondary metabolite. Neoaspergillic acid can be isolated from the endophytic fungus Aspergillus sp. SPH2. Neoaspergillic acid has potent antifungal activity against Alternaria alternata, Botrytis cinerea and Fusarium oxysporum. Neoaspergillic acid appears during the exponential phase of fungal growth. Neoaspergillic acid also antitumor and antibacterial effects.
    Neoaspergillic acid
  • HY-N16430
    Neovasinin 111897-37-1 98%
    Neovasinin is a phytotoxin that can be produced by the fungus Neocosmospora vasinfecta. Neovasinin exhibits toxic effects on soybean plants.
    Neovasinin
  • HY-N16432
    Nidulol 17811-38-0 98%
    Nidulol is a compound that can be isolated from the fungus Aspergillus nidulans metabolites. Nidulol shows no phytotoxic activity against Zea mays and Medicago polymorpha L. at a concentration of 5 mM.
    Nidulol
  • HY-N16437
    Panowamycin A 1375224-55-7 98%
    Panowamycin A is an isochroman compound that can be produced by Streptomyces sp. K07-0010. Panowamycin A exhibits antitrypanosomal activity against the Trypanosoma brucei brucei GUTat 3.1 strain (IC50: 0.40 μg/mL). Panowamycin A shows weak cytotoxicity towards human fetal lung fibroblast MRC-5 cells (IC50: 2.95 μg/mL). Panowamycin A can be used for research in the field of antitrypanosomal studies.
    Panowamycin A
  • HY-N16441
    Pulvic acid 26548-70-9
    Pulvic acid (Compound 3), a butenolide, is a microbial secondary metabolite. Pulvic acid can be isolated from the marine-derived fungus Aspergillus terreus Gwq-48. Pulvic acid has significant antiviral activity with an IC50 of 29.1 μg/mL for influenza A H1N1 virus. Pulvic acid can be used for influenza virus infections research.
    Pulvic acid
Cat. No. Product Name / Synonyms Application Reactivity