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Cat. No.: HY-N16441

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Pulvic acid

Pulvic acid (Compound 3), a butenolide, is a microbial secondary metabolite. Pulvic acid can be isolated from the marine-derived fungus Aspergillus terreus Gwq-48. Pulvic acid has significant antiviral activity with an IC₅₀ of 29.1 μg/mL for influenza A H1N1 virus. Pulvic acid can be used for influenza virus infections research.

For research use only. We do not sell to patients.

CAS No.: 26548-70-9
Formula: C₁₈H₁₂O₅
Molecular Weight:308.28

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Pulvic acid Chemical Structure

CAS No.: 26548-70-9

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Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
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Help & FAQs
Classifications
Bioz

Biological Activity

Description

All Endogenous Metabolite Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	CC₅₀	>250 μg/mL Compound: 3	Cytotoxicity against human A549 cells assessed as cell viability after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell viability after 72 hrs by MTT assay	[PMID: 23411074]
MDCK	CC₅₀	>250 μg/mL Compound: 3	Cytotoxicity against MDCK cells assessed as cell viability after 72 hrs by MTT assay Cytotoxicity against MDCK cells assessed as cell viability after 72 hrs by MTT assay	[PMID: 23411074]
MDCK	IC₅₀	29.1 μg/mL Compound: 3	Antiviral activity against Influenza A virus (A/Puerto Rico/8/1934(H1N1)) infected in MDCK cells assessed as protection against virus-induced cytopathic effect after 48 hrs by crystal violet staining method Antiviral activity against Influenza A virus (A/Puerto Rico/8/1934(H1N1)) infected in MDCK cells assessed as protection against virus-induced cytopathic effect after 48 hrs by crystal violet staining method	[PMID: 23411074]

Chemical Information

CAS No. 26548-70-9
Molecular Weight 308.28
Formula C₁₈H₁₂O₅
SMILES

OC(/C(C1=CC=CC=C1)=C2C(O)=C(C3=CC=CC=C3)C(O\2)=O)=O
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Microorganisms
Aspergillus terreus
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gao H, et al. Aspulvinones from a mangrove rhizosphere soil-derived fungus Aspergillus terreus Gwq-48 with anti-influenza A viral (H1N1) activity. Bioorg Med Chem Lett. 2013 Mar 15;23(6):1776-8. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Pulvic acid

All Endogenous Metabolite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Pulvic acid Related Classifications

HY-N16441 Related Classifications