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Cat. No.: HY-N16418

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Epanorin

Epanorin is a secondary metabolite of the Acarospora lichenic species Epanorin can inhibit cancer cells proliferation, ROS production and induce G0/G1 phase arrest. Epanorin shows antibacterial activity. Epanorin can be used for the researches of cancer and infection, such as breast cancer and S. pneumonia infection.

For research use only. We do not sell to patients.

CAS No.: 18463-10-0
Formula: C₂₅H₂₅NO₆
Molecular Weight:435.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Epanorin Chemical Structure

CAS No.: 18463-10-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

In Vitro

Epanorin shows potent inhibitory activity against breast cancer cell line (up to 80%) and moderate inhibitory activity for meningioma (up to 40%)^[1].
Epanorin (28 μM) reduces cell colonies in MCF-7 cells^[1].
Epanorin (28 μM, 48 h) reduces ROS production in Doxorubicin (HY-15142A)-induced MCF-7 cells^[1].
Epanorin (28 μM, 48 h) induces G0/G1 phase arrest in MCF-7 cells^[1].
Epanorin (28 μM, 12 h) does not induce detectable DNA fragmentation in MCF-7 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cycle Analysis^[1]

Cell Line:

MCF-7 cells
Concentration:

28 μM
Incubation Time:

48 h
Result:

Increased the cells on G0 phase.
Reduced cells on S phase.

Chemical Information

CAS No. 18463-10-0
Molecular Weight 435.47
Formula C₂₅H₂₅NO₆
SMILES

COC([C@H](CC(C)C)NC(/C(C1=CC=CC=C1)=C2C(O)=C(C3=CC=CC=C3)C(O/2)=O)=O)=O
Structure Classification
- Others
Initial Source
- Microorganisms
Acarospora schleicheri
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Palacios-Moreno J, et al. Epanorin, a lichen secondary metabolite, inhibits proliferation of MCF-7 breast cancer cells. Biol Res. 2019 Oct 10;52(1):55. [Content Brief]

[2]. Timbreza L P, et al. Antibacterial activities of the lichen Ramalina and Usnea collected from Mt. Banoi, Batangas and Dahilayan, Bukidnon, against multi-drug resistant (MDR) bacteria[J]. Austrian Journal of Mycology, 2017, 26: 27-42.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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