Mycoleptone A
Mycoleptone A is an azafluorenone compound. Mycoleptone A exhibits certain anti-leishmanial activity, with an LD50 of 28.5 μM against L. major. Mycoleptone A shows cytotoxicity against human prostate cancer cell line PC3, with an IC50 of 10.0 μM. Mycoleptone A can be used in research on anti-parasitic and anti-tumor aspects.
For research use only. We do not sell to patients.
- CAS No.: 1532554-02-1
- Formula: C23H24O8
- Molecular Weight:428.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Parasite Isoforms
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Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HCT-8 | IC50 |
>58 μM
Compound: 2, Mycoleptone A
|
Cytotoxicity against human HCT8 cells by colorimetric method
Cytotoxicity against human HCT8 cells by colorimetric method
|
[PMID: 24387625] |
| HL-60 | IC50 |
>58 μM
Compound: 2, Mycoleptone A
|
Cytotoxicity against human HL60 cells by colorimetric method
Cytotoxicity against human HL60 cells by colorimetric method
|
[PMID: 24387625] |
| Lymphocyte | IC50 |
>58 μM
Compound: 2, Mycoleptone A
|
Cytotoxicity against human lymphocytes by colorimetric method
Cytotoxicity against human lymphocytes by colorimetric method
|
[PMID: 24387625] |
| MDA-MB-435 | IC50 |
>58 μM
Compound: 2, Mycoleptone A
|
Cytotoxicity against human MDA-MB-435 cells by colorimetric method
Cytotoxicity against human MDA-MB-435 cells by colorimetric method
|
[PMID: 24387625] |
| PC-3 | IC50 |
10 μM
Compound: 2, Mycoleptone A
|
Cytotoxicity against human PC3 cells by colorimetric method
Cytotoxicity against human PC3 cells by colorimetric method
|
[PMID: 24387625] |
| SF-295 | IC50 |
>58 μM
Compound: 2, Mycoleptone A
|
Cytotoxicity against human SF295 cells by colorimetric method
Cytotoxicity against human SF295 cells by colorimetric method
|
[PMID: 24387625] |
Chemical Information
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CAS No. 1532554-02-1
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Molecular Weight 428.43
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Formula C23H24O8
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SMILES
CC(OC=C1[C@H](O)[C@@]2(C)O)=CC1=C(CC3=C4C=C(OC=C4[C@H](O)[C@](O)(C)C3=O)C)C2=O
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Structure Classification
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Initial Source
Mycoleptodiscus indicus
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)