2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N17584
    (7S,8R)-Dihydrodehydrodiconiferyl alcohol-9-β-D-glucopyranoside 126371-34-4
    (7S,8R)-Dihydrodehydrodiconiferyl alcohol-9-β-D-glucopyranoside (compound 1) is a lignan found in the dried roots of Pulsatilla koreana and Sortase A inhibitor with an IC50 of 67.7 μM against Streptococcus mutans OMZ65 Sortase A. (7S,8R)-Dihydrodehydrodiconiferyl alcohol-9-β-D-glucopyranoside can be used for the research of dental caries.
    (7S,8R)-Dihydrodehydrodiconiferyl alcohol-9-β-D-glucopyranoside
  • HY-N17621
    Chinenol A 633294-59-4 98%
    Chinenol A is an antibacterial agent that can be found in the aerial part of Helwingia chinensis. Chinenol A can be used for the research of bacterial infections (staphylococcus aureus infection, mycobacterium tuberculosis infection, streptococcus pneumonia infection).
    Chinenol A
  • HY-N17638
    7-Oxomogroside V 942612-72-8 98%
    7-Oxomogroside V is a cucurbitane-type glycoside isolated from the fruits of Siraitia grosvenorii. 7-Oxomogroside V inhibits the activation of Epstein-Barr virus early antigen (EBV-EA) induced by TPA (HY-18739). 7-Oxomogroside V also exerts weak inhibitory effects on the activation of the nitric oxide donor NOR 1. 7-Oxomogroside V is applicable to tumor-related research.
    7-Oxomogroside V
  • HY-N17716
    4'-O-β-D-Glucosyl-5,3'-dihydroxy-7-methoxyflavanone 114219-00-0 98%
    4'-O-β-D-Glucosyl-5,3'-dihydroxy-7-methoxyflavanone (Compound 3) (4'-O-β-D-Glucosyl-7-methoxy-eriodictiol) is a flavonoid. 4'-O-β-D-Glucosyl-5,3'-dihydroxy-7-methoxyflavanone can be isolated from the plant Aerva persica.
    4'-O-β-D-Glucosyl-5,3'-dihydroxy-7-methoxyflavanone
  • HY-N17718
    Urushiol (15:3) 83543-37-7
    Ursolic acid (15:3) (Compound 4) is a type of resiniferatoxin compound that can be found in the leaves of the tree Rhus verniciflua. Ursolic acid (15:3) exhibits moderate inhibitory activity against HIV-1 reverse transcriptase (b HIV-1 reverse transcriptase), with an IC50 value of 55.36 μM. Ursolic acid (15:3) shows strong cytotoxicity against both PC-3 and MRC-5 cells. Ursolic acid (15:3) can be used in the research of anti-HIV-1 infection and prostate cancer.
    Urushiol (15:3)
  • HY-N17728
    11βh,13-Dihydroparthenolide 2513-76-0 98%
    11βh,13-Dihydroparthenolide (Compound 314) is a metabolite of Parthenolide (HY-N0141), which can be produced by biotransformation of filamentous fungi.
    11βh,13-Dihydroparthenolide
  • HY-N17734
    2-Deethoxy-2-hydroxyphantomolin 821799-76-2 98%
    2-Deethoxy-2-hydroxyphantomolin, Germacranolide, is an Antifungal and Antibacterial agent. 2-Deethoxy-2-hydroxyphantomolin can be isolated from Elephantopus tomentosus Linn and E. mollis. 2-Deethoxy-2-hydroxyphantomolin is moderately active against Candida albicans (14 mm clearing zone) and slightly active against Escherichia coli (12 mm), Pseudomonas aeruginosa (12 mm), Bacillus subtilis (14 mm), and Trichophyton mentagrophytes (13 mm).
    2-Deethoxy-2-hydroxyphantomolin
  • HY-N17741
    Melanochromone 350229-67-3 98%
    Melanochromone is an HIV-1 reverse transcriptase inhibitor that exhibits anti-HIV-1 activity. Melanochromone can be used in research related to HIV-1 infection.
    Melanochromone
  • HY-N17764
    Meliasendanin D 4'-O-β-D-glucopyranoside 1931100-79-6
    Meliasendanin D 4'-O-β-D-glucopyranoside (Example 1) is a neolignan-type lignan that may have potential functions in controlling blood sugar, lowering blood pressure, and exhibiting antibacterial, anti-inflammatory, analgesic, or immunomodulatory effects, which require further experimental verification.
    Meliasendanin D 4'-O-β-D-glucopyranoside
  • HY-N17780
    Picfeoside A 871115-75-2
    Picfeoside A is a phenylethanoid glycoside compound that can be isolated from Picria felterrae Lour. Picfeoside A can be used in research related to diseases such as fever, herpes infections, cancer, and inflammation.
    Picfeoside A
  • HY-N17784
    Peiioside A 1610618-94-4
    Peiioside A is a phenylethanoid glycoside compound that can be isolated from the leaves and stems of Callicarpa longissima. Callicarpa longissima has traditional medicinal uses for treating colds, coughs, arthritis, and bleeding, and can be used in the research of anti-inflammatory and antibacterial agents, as well as in neuroprotection-related fields.
    Peiioside A
  • HY-N1780R
    3,4-Dimethoxyphenol (Standard) 2033-89-8 98%
    3,4-Dimethoxyphenol (Standard) is the analytical standard of Lithocholic acid. This product is intended for research and analytical applications. 3,4-Dimethoxyphenol is a plant-derived phenylpropanoid compound and can use as a whitening agent in cosmetics. 3,4-Dimethoxyphenol exhibits broad-spectrum antimicrobial activity. 3,4-Dimethoxyphenol has tyrosinase-inhibiting activity. 3,4-Dimethoxyphenol has potent antioxidant effect isolated from the bacterial fermentation broth. 3,4-Dimethoxyphenol can be used for the study of infection.
    3,4-Dimethoxyphenol (Standard)
  • HY-N17850
    5-Hydroxy-6,7-dimethoxyflavone 2035-05-4
    5-Hydroxy-6,7-dimethoxyflavone is an orally active inhibitor of ferroptosis (Ferroptosis). 5-Hydroxy-6,7-dimethoxyflavone inhibits H1N1 virus-induced ferroptosis by upregulating the expression of SLC7A11 and GPX4. 5-Hydroxy-6,7-dimethoxyflavone alleviates inflammatory responses and inhibits apoptosis by suppressing the activation of the NF-κB and p38 MAPK signaling pathways. 5-Hydroxy-6,7-dimethoxyflavone can be used in studies related to H1N1 influenza virus infection.
    5-Hydroxy-6,7-dimethoxyflavone
  • HY-N17857
    Quercetin 3'-methoxy-3-O-α-L-arabinofuranoside 5041-66-7
    Quercetin 3'-methoxy-3-O-α-L-arabinofuranoside is a weak inhibitor of α-glucosidase, which can found in the leaves and twigs of Fagus hayatae.
    Quercetin 3'-methoxy-3-O-α-L-arabinofuranoside
  • HY-N17858
    Guajaphenone A 1661877-86-6
    Guajaphenone A is a benzophenone glycoside antibacterial agent that can be found in the leaves of Psidium guajava L. Guajaphenone A inhibits the growth of Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli. Guajaphenone A is applicable to research related to bacterial infections.
    Guajaphenone A
  • HY-N17907
    1-(4-Hydroxy-3-methoxyphenyl)dec-5-en-3-one 219946-07-3 98%
    1-(4-Hydroxy-3-methoxyphenyl)dec-5-en-3-one is an aryldecanone termite antifeedant compound found in the seeds of Aframomum melegueta. 1-(4-Hydroxy-3-methoxyphenyl)dec-5-en-3-one acts as a feeding deterrent against Reticulitermes speratus workers in a choice filter paper disk bioassay.
    1-(4-Hydroxy-3-methoxyphenyl)dec-5-en-3-one
  • HY-N17963
    Cappariloside A 229483-41-4 98%
    Cappariloside A is a larvicide that exhibits larvicidal activity against Aedes aegypti larvae and reduces larval glutathione-S-transferase activity. Cappariloside A also possesses antiviral activity, decreases the level of phosphorylated STAT1 in cells, inhibits the replication of influenza viruses H1N1, H3N2, PIV3 and ADV, and downregulates the expression of IL-6, IP-10, MIG, RANTES/CCL-5, IFN-β and IL-29. Cappariloside A suppresses the inflammatory response induced by mouse lung-adapted influenza virus strains. Cappariloside A can be used in studies related to larvicidal applications and influenza virus infection.
    Cappariloside A
  • HY-N17982
    Vanillic acid 4-O-β-D-glucopyranoside 879627-80-2 98%
    Vanillic acid 4-O-β-D-glucopyranoside is a vanillic acid glycoside with moderate antioxidant activity. Vanillic acid 4-O-β-D-glucopyranoside scavenges DPPH free radicals and superoxide anion radicals, and inhibits AAPH-induced lipid peroxidation in the linoleic acid system. The IC50 value of Vanillic acid 4-O-β-D-glucopyranoside against HIV-1 integrase is >100 μg/mL, indicating that it is not an effective HIV-1 integrase inhibitor. Vanillic acid 4-O-β-D-glucopyranoside is isolable from the ethyl acetate extract of Gardeniae Fructus.
    Vanillic acid 4-O-β-D-glucopyranoside
  • HY-N17997
    Pilosulyne D 1924616-12-5 98%
    Pilosulyne D is a polyyne found in the roots of Codonopsis pilosula.
    Pilosulyne D
  • HY-N17999
    10-Hydroxypheophorbide A 83688-53-3 98%
    10-Hydroxypheophorbide A is a chlorophyll-related compound found in the leaves of
    Neptunia oieracea. 10-Hydroxypheophorbide A inhibits the activation of tumor promoter-induced Epstein-Barr virus (EBV) activation. 10-Hydroxypheophorbide A exhibits photo-induced cytotoxicity in cancer cells.
    10-Hydroxypheophorbide A
Cat. No. Product Name / Synonyms Application Reactivity