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Cat. No.: HY-N17734

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2-Deethoxy-2-hydroxyphantomolin

2-Deethoxy-2-hydroxyphantomolin, Germacranolide, is an Antifungal and Antibacterial agent. 2-Deethoxy-2-hydroxyphantomolin can be isolated from Elephantopus tomentosus Linn and E. mollis. 2-Deethoxy-2-hydroxyphantomolin is moderately active against Candida albicans (14 mm clearing zone) and slightly active against Escherichia coli (12 mm), Pseudomonas aeruginosa (12 mm), Bacillus subtilis (14 mm), and Trichophyton mentagrophytes (13 mm).

For research use only. We do not sell to patients.

CAS No.: 821799-76-2
Formula: C₁₉H₂₂O₆
Molecular Weight:346.37

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

2-Deethoxy-2-hydroxyphantomolin Chemical Structure

CAS No.: 821799-76-2

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

2-Deethoxy-2-hydroxyphantomolin (20.0 mg/mL; 24 h) inhibits Staphylococcus aureus with an inhibition zone diameter of 31.0 mm in an in vitro disk diffusion assay^[1].
2-Deethoxy-2-hydroxyphantomolin is moderately active against Candida albicans (14 mm clearing zone, AI = 0.4) and slightly active against Escherichia coli (12 mm, AI = 0.2), Pseudomonas aeruginosa (12 mm, AI = 0.2), Bacillus subtilis (14 mm, AI = 0.4), and Trichophyton mentagrophytes (13 mm, AI = 0.3), with no activity against Staphylococcus aureus and Aspergillus niger^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 821799-76-2
Molecular Weight 346.37
Formula C₁₉H₂₂O₆
SMILES

CC(C(O[C@@H]1[C@]2([H])[C@@](OC(C2=C)=O)([H])[C@@]3([H])O[C@](C=C3C)(/C=C(C1)/C)O)=O)=C
Structure Classification
- Terpenoids
- Other Monoterpenes
Initial Source
- Plants
- Boraginaceae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wang B, et al. A new sesquiterpene lactone from Elephantopus tomentosus. J Asian Nat Prod Res. 2012;14(7):700-703. [Content Brief]

[2]. Ragasa, CB, et al. Antimicrobial terpenoids from elephantopus mollis. NRCP Research Journal, 2009;10, Issue 1, 1-6

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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