A new sesquiterpene lactone from Elephantopus tomentosus

  • J Asian Nat Prod Res. 2012;14(7):700-3. doi: 10.1080/10286020.2012.682153.
Bei Wang  1 ,  Wen-Li Mei ,  Yan-Bo Zeng ,  Zhi-Kai Guo ,  Guo-Dao Liu ,  Hao-Fu Dai
Affiliations
  • 1. Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101, China.
PMID: 22582752 DOI: 10.1080/10286020.2012.682153
Abstract

A new sesquiterpene lactone, named tomenphantopin H (1), together with two known germacranolides, 2β-methoxy-2-deethoxy-8-O-deacylphantomolin-8-O-tiglinate (2) and 2-deethoxy-2-hydroxyphantomolin (3), was isolated from the whole plant of Elephantopus tomentosus Linn. The new compound was completely elucidated using a combination of 1D and 2D NMR techniques (COSY, HMQC, and HMBC) and HR-ESI-MS analyses. All compounds exhibited Antibacterial activity.

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