2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-114509R
    Anilazine (Standard) 101-05-3
    Anilazine (Standard) is the analytical standard of Anilazine. This product is intended for research and analytical applications. Anilazine is a fungicide and inhibit the growth of Rhizobium sp. and E. coli. Anilazine inhibits glucose oxidation and succinate oxidation and also inhibits in vitro succinic dehydrogenase activity.
    Anilazine (Standard)
  • HY-114816S
    N-butyryl-L-Homoserine lactone-d5 2701379-46-4
    N-butyryl-L-Homoserine lactone-d5 is the deuterium labeled N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa.
    N-butyryl-L-Homoserine lactone-d5
  • HY-114844A
    L-Phenylalanyl-L-glutamic acid TFA
    L-Phenylalanyl-L-glutamic acid TFA (H-Phe-Glu-OH TFA) is a dipeptide present in the exudates of alfalfa seedlings, which exhibits high affinity for PEPT2. L-Phenylalanyl-L-glutamic acid TFA can serve as the peptide scaffold of a tyrosyl-tRNA synthetase inhibitor against Staphylococcus aureus.
    L-Phenylalanyl-L-glutamic acid TFA
  • HY-114899R
    Azamethiphos (Standard) 35575-96-3
    Azamethiphos (Standard) is the analytical standard of Azamethiphos (HY-114899). This product is intended for research and analytical applications. Azamethiphos is an acetylcholinesterase inhibitor and insecticide. Azamethiphos covalently binds to acetylcholinesterase via phosphorylation, inhibits its activity, causes acetylcholine to accumulate in cholinergic synapses, triggers uncontrolled excitation of cholinergic sites, induces paralysis and leads to death. Azamethiphos can be used as a bath insecticide in salmonid aquaculture to control sea lice infestations, and it exerts acute toxicity to European lobster larvae, including mortality and movement disorders.
    Azamethiphos (Standard)
  • HY-114899S
    Azamethiphos-d6 1189894-02-7 99.01%
    Azamethiphos-d6 is deuterated labeled Azamethiphos (HY-114899). Azamethiphos is an acetylcholinesterase inhibitor and insecticide. Azamethiphos covalently binds to acetylcholinesterase via phosphorylation, inhibits its activity, causes acetylcholine to accumulate in cholinergic synapses, triggers uncontrolled excitation of cholinergic sites, induces paralysis and leads to death. Azamethiphos can be used as a bath insecticide in salmonid aquaculture to control sea lice infestations, and it exerts acute toxicity to European lobster larvae, including mortality and movement disorders.
    Azamethiphos-d6
  • HY-115127S
    3-Methylanisole-d3 20369-34-0 98%
    3-Methylanisole-d3 (m-Methoxytoluene-d3; m-MetHYlanisole-d3) is the deuterium labeled 3-Methylanisole (HY-115127). Methylanisole is a volatile metabolite produced by Penicillium strains growing on barley. 3-Methylanisole serves as a precursor for the biotechnological production of vanillin.
    3-Methylanisole-d3
  • HY-115249R
    Metronidazole acetic acid (Standard) 1010-93-1 98%
    Metronidazole acetic acid (Standard) is the analytical standard of Metronidazole acetic acid. This product is intended for research and analytical applications. Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa.
    Metronidazole acetic acid (Standard)
  • HY-115364R
    Parbendazole (Standard) 14255-87-9 98%
    Parbendazole (Standard) is the analytical standard of Parbendazole. This product is intended for research and analytical applications. Parbendazole is a potent inhibitor of microtubule assembly, destabilizes tubulin, with an EC50 of 530 nM, and exhibits a broad-spectrum anthelmintic activity.
    Parbendazole (Standard)
  • HY-115364S
    Parbendazole-d3 1613439-58-9 98%
    Parbendazole-d3 is the deuterium labeled Parbendazole. Parbendazole is a potent inhibitor of microtubule assembly, destabilizes tubulin, with an EC50 of 530 nM, and exhibits a broad-spectrum anthelmintic activity.
    Parbendazole-d3
  • HY-115393A
    N-Heptanoyl-L-homoserine lactone 177158-20-2 98%
    N-Heptanoyl-L-homoserine lactone is a member of N-acyl-homoserine lactone family. N-acyl-homoserine lactones (AHL) can regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella, and are involved in quorum sensing, cell to cell communication among bacteria.
    N-Heptanoyl-L-homoserine lactone
  • HY-115584S
    Lufenuron-13C6 2749747-70-2 98%
    Lufenuron-13C6 is a 13C-labeled Lufenuron. Lufenuron is a lipophilic benzoylurea insecticide and a chitin synthesis inhibitor that can used for flea and fish lice control. Lufenuron inhibits moulting of arthropods.
    Lufenuron-13C6
  • HY-115965R
    VP-4604 (Standard) 64268-93-5 98%
    VP-4604 (Standard) is the analytical standard of VP-4604. This product is intended for research and analytical applications. VP-4604 is a potent anti-methicillin-resistant Staphylococcus aureus (MRSA) agent. VP-4604 exhibits significant microbial growth inhibition toward Staphylococcus aureus (ATCC 43300) with MIC of 4-8 μg/mL. VP-4604 inhibits the growth of methicillin‐resistant Staphylococcus aureus with growth inhibition >95%[1].
    VP-4604 (Standard)
  • HY-116021S
    Buquinolate-13C3 98%
    Buquinolate-13C3 is the 13C3 labeled Buquinolate. Buquinolate is a quinoline derivative, which is developed as a coccidiostat for the prevention of coccidiosis in poultry.
    Buquinolate-13C3
  • HY-116214S
    Cyprodinil-d5 1773496-67-5 98%
    Cyprodinil-d5(CGA-219417-d5) is the deuterium labeled Cyprodinil (HY-116214). Cyprodinil (CGA-219417) is a broad-spectrum anilinopyrimidine fungicide and an activator of the aryl hydrocarbon receptor. Cyprodinil also has anti-androgenic and androgenic activities. Cyprodinil can inhibit the biosynthesis of methionine in plant-pathogenic fungi and protect fruits and vegetables from a variety of pathogens.
    Cyprodinil-d5
  • HY-116282P
    Dextran sulfate, high sulfate (MW 5000) 9011-18-1 98%
    Dextran sulfate, high sulfate (MW 5000) is a type of dextran sulfate with a high degree of sulfation. Dextran sulfate sodium can be used to induce ulcerative colitis models, and the greater the total number of sulfur atoms, the stronger the induced toxic effect. Dextran sulfate has certain antibacterial activity, and can form the ionic cross-linking core of nanoparticles together with chitosan, serving as a highly efficient dressing material to accelerate wound healing.
    Dextran sulfate, high sulfate (MW 5000)
  • HY-116448R
    Metaflumizone (Standard) 139968-49-3
    Metaflumizone (Standard) is the analytical standard of Metaflumizone. This product is intended for research and analytical applications. Metaflumizone is a semicarbazone insecticide, acts as a potent sodium channel blocker.
    Metaflumizone (Standard)
  • HY-116474R
    Viridicatol (Standard) 14484-44-7
    Viridicatol (Standard) is the analytical standard of Viridicatol (HY-116474). This product is intended for research and analytical applications. Viridicatol is a quinolone alkaloid with anti-inflammatory, antibacterial, antifungal, osteogenic and chondrogenic activities. Viridicatol reduces the phosphorylation levels of ERK, JNK, p38 and STAT6; inhibits MMP-2, MMP-9, NF-κB signaling pathway and PTP1B; downregulates genes related to mast cell activation; and binds to SHN3 to activate the Wnt/SHN3 signaling pathway. Viridicatol inhibits the expression of pro-inflammatory mediators and cytokines, and promotes osteogenic/chondrogenic differentiation. Viridicatol can be used in studies related to fibrosarcoma, allergy, bacterial infection, fungal infection and osteoporosis.
    Viridicatol (Standard)
  • HY-116535A
    DL-threo-PPMP hydrochloride 139974-41-7 98.05%
    DL-threo-PPMP hydrochloride is an inhibitor of sphingosine synthetase in Plasmodium falciparum. DL-threo-PPMP hydrochloride inhibits the activity of sphingosine synthetase (sphingosine synthetase) by binding to a substrate that mimics sphingosine. This inhibition leads to a rapid decline in sensitive sphingomyelin synthase (SSS) activity, selectively disrupting the interconnected tubular network of TVM in the cytoplasm of the host cell, and this inhibition also blocks the proliferation of the parasite. DL-threo-PPMP hydrochloride can be used in the study of malaria parasite biology and the search for new antimalarial strategies.
    DL-threo-PPMP hydrochloride
  • HY-116568S
    Prothioconazole-d4 98%
    Prothioconazole-d4 (JAU-6476-d4) is the deuterium labeled Prothioconazole (HY-116568). Prothioconazole is a triazolinthione fungicide. Prothioconazole is a CYP51 inhibitor.
    Prothioconazole-d4
  • HY-116934R
    5-Pentadecylresorcinol (Standard) 3158-56-3
    5-Pentadecylresorcinol (Standard) is the analytical standard of 5-Pentadecylresorcinol. This product is intended for research and analytical applications. 5-Pentadecylresorcinol (Adipostatin A) is a glycerol-3-phosphate dehydrogenase (GPDH) inhibitor with an IC50 of 4.1 μM. Adipostatin A shows good larvicidal activity against Aedes aegypti.
    5-Pentadecylresorcinol (Standard)
Cat. No. Product Name / Synonyms Application Reactivity