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Cat. No.: HY-116282P

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Dextran sulfate, high sulfate (MW 5000)

Dextran sulfate, high sulfate (MW 5000) is a type of dextran sulfate with a high degree of sulfation. Dextran sulfate sodium can be used to induce ulcerative colitis models, and the greater the total number of sulfur atoms, the stronger the induced toxic effect. Dextran sulfate has certain antibacterial activity, and can form the ionic cross-linking core of nanoparticles together with chitosan, serving as a highly efficient dressing material to accelerate wound healing.

For research use only. We do not sell to patients.

CAS No.: 9011-18-1
Molecular Weight:5000 (Average)

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Dextran sulfate, high sulfate (MW 5000) Chemical Structure

CAS No.: 9011-18-1

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
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Classifications
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Biological Activity

Description

In Vivo

Dextran sulfate sodium (5% (w/v); p.o.; ad libitum; 7 days) induces colitis in female BALB/c Cr Slc mice. Low-molecular-weight (5kD) dextran sulfate mainly causes mild, focal lesions in the cecum and proximal colon, whereas high-molecular-weight (40kD) dextran sulfate induces more severe, diffuse colitis, with lesions predominantly localized in the distal colon^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 9011-18-1
Molecular Weight 5000 (Average)
SMILES

[Dextran sulfate sodium salt]
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kitajima S, et al. Histological analysis of murine colitis induced by dextran sulfate sodium of different molecular weights. Exp Anim. 2000;49(1):9-15. [Content Brief]

[2]. Darwish MM, et al. Aloe Vera coated Dextran Sulfate/Chitosan nanoparticles (Aloe Vera @ DS/CS) encapsulating Eucalyptus essential oil with antibacterial potent property. J Biomater Sci Polym Ed. 2023 Apr;34(6):810-827.
[Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Dextran sulfate, high sulfate (MW 5000)

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Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References

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Dextran sulfate, high sulfate (MW 5000)

Dextran sulfate sodium salt (MW 35000-45000)

Dextran sulfate sodium salt (MW 5000)

Dextran sulfate sodium salt (MW 450000-550000)

Dextran sulfate sodium salt (MW 4500-5500)

Dextran sulfate sodium salt (MW>500000)

Dextran sulfate, low sulfate (MW 40000)

Dextran sulfate sodium salt (MW 16000-24000)

Dextran sulfate sodium salt (MW 9000-20000)

Dextran sulfate, low sulfate (MW 5000)

Dextran sulfate sodium salt (MW 6500-10000)

Methyl cellulose(Viscosity:100000mPa.s)

FITC-Dextran (MW 4000)

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Bioz

Dextran sulfate, high sulfate (MW 5000)

Dextran sulfate sodium salt (MW 35000-45000)

Dextran sulfate sodium salt (MW 5000)

Dextran sulfate sodium salt (MW 450000-550000)

Dextran sulfate sodium salt (MW 4500-5500)

Dextran sulfate sodium salt (MW>500000)

Dextran sulfate, low sulfate (MW 40000)

Dextran sulfate sodium salt (MW 16000-24000)

Dextran sulfate sodium salt (MW 9000-20000)

Dextran sulfate, low sulfate (MW 5000)

Dextran sulfate sodium salt (MW 6500-10000)

Methyl cellulose(Viscosity:100000mPa.s)

FITC-Dextran (MW 4000)

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Dextran sulfate, high sulfate (MW 5000) Related Classifications

HY-116282P Related Classifications

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