2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-125074
    PNU 142300 368891-69-4 98%
    PNU 142300 is an inactive metabolite of the oxazolidinone antibiotic Linezolid (HY-10394).
    PNU 142300
  • HY-125084
    NEU617 1432450-82-2 98%
    NEU617 is an anti-parasite agent. NEU617 inhibits the proliferation for the HAT (human African trypanosomiasis) pathogen (EC50: 42 nM for Trypanosoma brucei, 1.8 μM for T. cruzi). NEU617 is a derivative of Lapatinib (HY-50898).
    NEU617
  • HY-125104
    Mirosamicin 73684-69-2 98%
    Mirosamicin is an antibiotic with high antibacterial activity that targets a wide range of gram-positive bacteria and certain Gram-negative bacteria as well as mycoplasma. Mirosamicin can be used for research in the field of food safety monitoring.
    Mirosamicin
  • HY-125117
    Simocyclinone D8 301845-97-6 98%
    Simocyclinone D8 is an anthracycline antibiotic with antibacterial and antitumor activity against Gram-positive bacteria. Simocyclinone D8 inhibits DNA gyrase and thus has an inhibitory effect on a variety of tumor cell lines.
    Simocyclinone D8
  • HY-125124
    Chamaejasmenin D 865852-47-7 98%
    Chamaejasmenin D is an antimitotic and antifungal agent.
    Chamaejasmenin D
  • HY-125152
    Candicidin D 39372-30-0 98%
    Candicidin D (CndD) is an antibiotic, which exhibits antifungal activity through interaction with steroids in cell membranes. Candicidin D inhibits S. cerevisiae, Candida albicans and other Candida spp. with MIC of 0.25-1 μg/mL in RPMI-1640 medium.
    Candicidin D
  • HY-125163
    MM 47755 117620-87-8 98%
    MM 47755 (8-O-Methyltetrangomycin; 6-Deoxy-8-O-methylrabelomycin) is an antibiotic with antibacterial activity. MM 47755 can be isolated from Streptomyces.
    MM 47755
  • HY-125188
    NEU-4438 2306305-57-5 98%
    NEU-4438 is an antimalarial agent. NEU-4438 inhibits DNA synthesis, reduces AMPK-γ, and increases Clathrin heavy chain. NEU-4438 exhibits antiparasitic activity against Trypanosoma brucei. NEU-4438 reduces trypanosome tissue burden in a chronic HAT mouse model.
    NEU-4438
  • HY-125258
    EBOV-IN-11 752216-12-9 98%
    EBOV-IN-11 is a protein phosphatase 1 (PP1) inhibitor, with Kd values of 1.88 nM and 8.01 nM against wild-type and quadruple-mutant PP1, respectively. EBOV-IN-11 potently inhibits the replication and transcription of EBOV-eGFP virus. EBOV-IN-11 can be used in studies related to Ebola virus infection.
    EBOV-IN-11
  • HY-125322
    Reveromycin C 144860-69-5 98%
    Reveromycin C is a polyketide originally isolated from Streptomyces that has antifungal activity against C. albicans (MICs=2.0 and >500 μg/mL at pH 3 and 7.4, respectively). Reveromycin C inhibits EGF-induced mitogenic activity in the Balb/MK mouse epidermal cell line. It also reverses the morphology of sarcoma-virus-transformed NRK rat kidney cells (EC50=1.58 μg/mL) and inhibits proliferation of KB cells and K562 human chronic myelogenous leukemia cells (IC50=2.0 μg/mL for both).
    Reveromycin C
  • HY-125326
    Spinosyn D 131929-63-0 99.00%
    Spinosyn D is one of the major components of Spinosad (HY-138800). Spinosad is a natural pesticide that shows biological activity against a range of insects including Lepidoptera.
    Spinosyn D
  • HY-125358
    Dactylfungin B 146935-36-6 98%
    Dactylfungin B (MK 2266 B) is an antifungal antibiotic that is active against Candida pseudotropicalis and other fungi, with an MIC value at <10 μg/mL.
    Dactylfungin B
  • HY-12538R
    Graveoline (Standard) 485-61-0 98%
    Graveoline (Standard) is the analytical standard of Graveoline (HY-12538). This product is intended for research and analytical applications. Graveoline (Rutamine) is an orally active alkaloid with various activities such as antifungal, antiparasitic, anti-inflammatory, and antitumor effects. Graveoline can induce tumor cell apoptosis and autophagy through a reactive oxygen species-mediated pathway. Graveoline has an MIC of 500 μg/mL for Candida albicans. Graveoline can be used in the research of various diseases such as tumors and liver injury.
    Graveoline (Standard)
  • HY-125395
    Altromycin G 134887-79-9 98%
    Altromycin G is an antibiotic that primarily targets Gram-positive bacteria and has strong antitumor activity.
    Altromycin G
  • HY-125416
    Streptothricin F 3808-42-2 98.34%
    Streptothricin F is a bactericidal antibiotic. Streptothricin F interacts with the 30S subunit of 70S ribosome. Streptothricin F shows rapid, bactericidal activity against highly drug-resistant, carbapenem-resistant Enterobacterales (CRE) (MIC50 and MIC90: 2 and 4 μM, respectively) and Acinetobacter baumannii.
    Streptothricin F
  • HY-125419
    Amythiamicin B 156620-48-3 98%
    Amythiamicin B is a trisubstituted pyridine thiopeptide with antibiotic properties against Gram-positive bacteria and activity against Plasmodium falciparum.
    Amythiamicin B
  • HY-125433
    A-75925 129467-48-7 98%
    A-75925 is a human immunodeficiency virus type 1 (HIV-1) proteinase inhibitor and can be utilized in HIV-1 rersearch.
    A-75925
  • HY-125455
    Ro 41-1879 141916-35-0 98%
    Ro 41-1879 is a catechol cephalosporin that has antimicrobial activity.
    Ro 41-1879
  • HY-125459
    L 705589 150220-81-8 98%
    L-705589 is a semi-synthetic penicillin-type antifungal agent. L-705589 exerts its antifungal effect by inhibiting the 1,3-β-D-glucan synthase in the fungal cell wall. L-705589 exhibits potent bactericidal activity against various Candida species (such as Candida albicans, Candida glabrata, Candida krusei, etc.) (MFC: 0.06 - 8 μg/mL), but has relatively weak activity against Cryptococcus neoformans (MFC: 32 - 64 μg/mL). L-705589 remains active against drug-resistant Candida strains and is not prone to inducing drug resistance. L-705589 significantly improves survival rates in the model of minor invasive aspergillosis.
    L 705589
  • HY-125473
    IDX375 1162665-52-2 98%
    IDX375 is a novel non-nucleoside inhibitor with selective inhibitory activity against HCV NS5B. IDX375 has good selectivity for genotypes 1a and 1b. The structure and binding site of IDX375 were confirmed by X-ray cocrystal studies.
    IDX375
Cat. No. Product Name / Synonyms Application Reactivity