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Cat. No.: HY-125117

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Simocyclinone D8

Simocyclinone D8 is an anthracycline antibiotic with antibacterial and antitumor activity against Gram-positive bacteria. Simocyclinone D8 inhibits DNA gyrase and thus has an inhibitory effect on a variety of tumor cell lines.

For research use only. We do not sell to patients.

CAS No.: 301845-97-6
Formula: C₄₆H₄₂ClNO₁₈
Molecular Weight:932.27

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Simocyclinone D8 Chemical Structure

CAS No.: 301845-97-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All DNA/RNA Synthesis Isoforms :

Chemical Information

CAS No. 301845-97-6
Molecular Weight 932.27
Formula C₄₆H₄₂ClNO₁₈
SMILES

O[C@@]12[C@@]34[C@@]([C@@H](C5=C(O)C([C@H]6C[C@H]([C@H](OC(C)=O)[C@@H](C)O6)OC(/C=C/C=C/C=C/C=C/C(NC7=C(C8=CC=C(O)C(Cl)=C8OC7=O)O)=O)=O)=CC=C5C4=O)O)([C@@H](O)C[C@@]1(CC(C)=CC2=O)O)O3
Structure Classification
- Antibiotics
Initial Source
- Microorganisms
Streptomyces antibioticus
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Schimana, et al. Simocyclinones, novel cytostatic angucyclinone antibiotics produced by Streptomyces antibioticus Tü 6040 I. taxonomy, fermentation, isolation and biological activities. The Journal of antibiotics 53.8 (2000): 779-787. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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- Description
Chemical Information
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Simocyclinone D8

All DNA/RNA Synthesis Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Simocyclinone D8 Related Classifications

HY-125117 Related Classifications