2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-133848
    Alanycarb 83130-01-2 98%
    Alanycarb (OK-135) is a broad-spectrum oxime carbamate insecticide with contact and oral toxicity. Alanycarb is effective against a wide variety of insect pests and is a pro-insecticide. The principal active molecule produced by the biological modification of Alanycarb within target organisms is methomyl.
    Alanycarb
  • HY-133929
    Gentamicin B 36889-15-3 99.79%
    Gentamicin B (SCH-14342) is an aminoglycoside antibiotic that can be isolated from Micromonospora echinospora. Gentamicin B can be used for the research of ataxia potential and renal toxicity.
    Gentamicin B
  • HY-134095
    Erythromycin A N-oxide 992-65-4 98%
    Erythromycin A N-oxide is a derivative of Erythromycin A and can be used in studies as a chiral selector in capillary electrophoresis.
    Erythromycin A N-oxide
  • HY-134111
    (Z)-9-Dodecenyl acetate 16974-11-1 98%
    (Z)-9-Dodecenyl acetate is a monounsaturated dodecenyl acetate, an EAG stimulant and an attraction inhibitor. (Z)-9-Dodecenyl acetate is a component of moth sex pheromones. (Z)-9-Dodecenyl acetate elicits electroantennogram (EAG) responses in the antennae of male Choristoneura rosaceana. (Z)-9-Dodecenyl acetate can be used in studies related to pest control.
    (Z)-9-Dodecenyl acetate
  • HY-134180
    rel-Carbovir monophosphate 144490-73-3 98%
    rel-Carbovir monophosphate is the -enantiomer of 2',3'-dideoxy-2',3'-didehydroguanosine and a carbocyclic analog of carbovir (CBV). Carbovir is an inhibitor of HIV replication that specifically inhibits the integration of proribonucleotides into DNA.
    rel-Carbovir monophosphate
  • HY-134220
    Doramectin monosaccharide 165108-44-1 98%
    Doramectin monosaccharide is an acid degradation product of Doramectin (HY-17035), a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. Doramectin undergoes acid-catalyzed hydrolysis to form doramectin monosaccharide.
    Doramectin monosaccharide
  • HY-134404
    6-Cl-PuTP 55673-61-5 98%
    6-Cl-PuTP is an ATP analog with active chlorine functionality. 6-Cl-PuTP can be used in viral disease related research.
    6-Cl-PuTP
  • HY-134518
    Erythromycin oxime 13127-18-9 98%
    Erythromycin oxime is an intermediate of Azithromycin (HY-17506). Azithromycin is a macrolide antibiotic useful for the treatment of a number of bacterial infections.
    Erythromycin oxime
  • HY-134561
    6-Amino-8-trifluoromethylphenanthridine 651055-83-3 98%
    6-Amino-8-trifluoromethylphenanthridine (6A-8tFP) is an antiprion agent and a derivative of 6-aminophenanthridine (HY-135189). It inhibits protein folding activity of the ribosome (PFAR) when used at a concentration of 150 μM.2 6A-8tFP directly competes with protein substrates for the ribosomal active site.
    6-Amino-8-trifluoromethylphenanthridine
  • HY-13465A
    VCH-916 free base 914778-92-0 98%
    VCH-916 free base is a thiophene derivative and non-nucleoside inhibitor of HCV NS5B polymerase. VCH-916 free base binds to Thumb Site II. VCH-916 free base can be used for the research of hepatitis c virus (hcv) infection.
    VCH-916 free base
  • HY-134922
    NS1-IN-1 181373-35-3 98%
    NS1-IN-1 (REDD1 inducer-1) is a naphthalimide compound and an NS1 inhibitor. NS1-IN-1 antagonizes influenza A virus NS1-mediated inhibition of host gene expression and induces REDD1 expression. NS1-IN-1 suppresses the mTORC1 signaling pathway via a TSC1-TSC2 dependent mechanism. NS1-IN-1 exhibits broad antiviral activity against influenza virus and vesicular stomatitis virus (VSV), with low toxicity.
    NS1-IN-1
  • HY-134931
    M090 1599466-63-3 98%
    M090 is the inhibitor for the hemagglutinin of influenza A Virus, that inhibits various influenza strains with EC50 of micromolar levels.
    M090
  • HY-13502R
    Mitoxantrone (Standard) 65271-80-9 98%
    Mitoxantrone (Standard) is the analytical standard of Mitoxantrone. This product is intended for research and analytical applications. Mitoxantrone is a potent topoisomerase II inhibitor. Mitoxantrone also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM. Mitoxantrone induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone shows antitumor activity. Mitoxantrone also has anti-orthopoxvirus activity with EC50s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively.
    Mitoxantrone (Standard)
  • HY-135062
    9-Methylguanine 5502-78-3 98%
    9-Methylguanine, a derivative of 8-mercaptoguanine, is a dihydropteroate synthase (DHPS) inhibitor with a Kd of 58 μM for E.coli DHPS (EcDHPS).
    9-Methylguanine
  • HY-135141
    Tetrahydroechinocandin B 54651-06-8 98%
    Tetrahydroechinocandin B (L 687,901) is a potent antifungal agent. Tetrahydroechinocandin B inhibits 1,3-beta-D-glucan synthesis with an IC50 of 0.85 μg/mL.
    Tetrahydroechinocandin B
  • HY-13516R
    Aloperine (Standard) 56293-29-9 98%
    Aloperine (Standard) is the analytical standard of Aloperine. This product is intended for research and analytical applications. Aloperine is an alkaloid in sophora plants such as Sophora alopecuroides L, which has shown anti-cancer, anti-inflammatory and anti-virus properties. Aloperine is widely used to treat patients with allergic contact dermatitis eczema and other skin inflammation in China. Aloperine induces apoptosis and autophagy in HL-60 cells.
    Aloperine (Standard)
  • HY-135196
    Mideplanin 122173-74-4 98%
    Mideplanin (MDL 62873) is an antimicrobial agent, semisynthetic amide derivative of Teicoplanin (HY-A0097). Mideplanin is highly active in vitro against staphylococci.
    Mideplanin
  • HY-13524R
    AG-1478 (Standard) 153436-53-4
    AG-1478 (Standard) is the analytical standard of AG-1478. This product is intended for research and analytical applications. AG-1478 (Tyrphostin AG-1478) is a selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM. AG-1478 has antiviral effects against HCV and encephalomyocarditis virus (EMCV).
    AG-1478 (Standard)
  • HY-135285
    Rifamexil 113102-19-5 98%
    Rifamexil is an antibiotic Rifamycin (HY-B1907A) derivative that is active against Mycobacterium avium complex and other mycobacteria.
    Rifamexil
  • HY-135330
    Lamivudine-13C,15N2 1391052-30-4 98%
    Lamivudine-13C,15N2 is a labelled impurity of Lamivudine (BCH-189). Lamivudine is a nucleoside reverse transcriptase inhibitors (NRTIs), and can inhibit HIV reverse transcriptase 1/2 and the reverse transcriptase of hepatitis B virus.
    Lamivudine-13C,15N2
Cat. No. Product Name / Synonyms Application Reactivity