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Cat. No.: HY-13465A

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VCH-916 free base

3 Cited Publications

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Based on 3 publication(s) in Google Scholar

VCH-916 free base is a thiophene derivative and non-nucleoside inhibitor of HCV NS5B polymerase. VCH-916 free base binds to Thumb Site II. VCH-916 free base can be used for the research of hepatitis c virus (hcv) infection.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 914778-92-0
Formule: C₂₆H₃₇NO₄S
Masse moléculaire:459.64

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

VCH-916 free base Chemical Structure

CAS No.: 914778-92-0

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Activité biologique
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- In Vitro
Chemical Information
Publications (3)
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Description

In Vitro

VCH-916 free base acts as a well-tolerated non-nucleoside inhibitor of HCV NS5B polymerase that binds to the Thumb Site II pocket^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 914778-92-0
Masse moléculaire 459.64
Formule C₂₆H₃₇NO₄S
SMILES

O=C(C1=C(N([C@H]2CC[C@H](OC)CC2)C([C@H]3CC[C@H](C)CC3)=O)C=C(C4=CCCCC4)S1)O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (3)

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Antiviral Res

Antiviral candidates against the hepatitis E virus (HEV) and their combinations inhibit HEV growth in in vitro. [Abstract]

2019 Oct:170:104570. PMID: 31362004
bioRxiv

2026 May 31.
bioRxiv

Linking sugar sensing to immunity in plants via O-glycosylation. [Abstract]

2026 May 10:2026.05.04.722566. PMID: 42146548

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Mayhoub AS, et al. Hepatitis C RNA-dependent RNA polymerase inhibitors: a review of structure-activity and resistance relationships; different scaffolds and mutations. Bioorg Med Chem. 2012;20(10):3150-3161. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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VCH-916 free base

3 Cited Publications

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- In Vitro
Chemical Information
Publications (3)
Pureté et documentation
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VCH-916 free base

Publications Citing Use of MedChemExpress (MCE) VCH-916 free base

Activité biologique

Chemical Information

Publications (3)

Pureté et documentation

Références

Calculators

Help & FAQs

VCH-916 free base Related Classifications

HY-13465A Related Classifications