2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-135330
    Lamivudine-13C,15N2 1391052-30-4 98%
    Lamivudine-13C,15N2 is a labelled impurity of Lamivudine (BCH-189). Lamivudine is a nucleoside reverse transcriptase inhibitors (NRTIs), and can inhibit HIV reverse transcriptase 1/2 and the reverse transcriptase of hepatitis B virus.
    Lamivudine-13C,15N2
  • HY-135422
    Nidulin 10089-10-8 98%
    Nidulin (Methylustin) is a depsidone isolated from a marine fungus Aspergillus unguis. Nidulin shows antifungal and antibacterial against pathogenetic strains, Pseudomonas aeruginosa, Methicillin-resistant Staphylococcus aureus and Candida albicans with inhibition zones of 9.5 mm, 9.0 mm and 9.0 mm, respectively. Nidulin exhibits potent larvicidality against brine shrimp.
    Nidulin
  • HY-135438
    Mollugogenol A 22550-76-1 98%
    Mollugogenol A is a fungal inhibitor. Mollugogenol A can cause damage to sperm membranes by increasing lipid peroxidation, exhibiting sperm-killing activity.
    Mollugogenol A
  • HY-135442
    Simeconazole 149508-90-7 98%
    Simeconazole is a demethylation inhibitor-class fungicide. Simeconazole prevents the infection of barley leaves by Blumeria graminis f sp hordei, inhibits the development of powdery mildew on barley and cucumber leaves, and exhibits cuticular membrane permeability in tomato fruits. Simeconazole can be used in research related to barley powdery mildew and cucumber powdery mildew.
    Simeconazole
  • HY-135445
    Prolylrapamycin 156223-31-3 98%
    Prolylrapamycin (21-Norrapamycin) is the derivative of Rapamycin (HY-10219). Prolylrapamycin exhibits antifungal activity, that inhibits Candida albicans, Saccharomyces cerevisiae, and Fusarium oxysporum with MIC of 0.125-2 μg/mL.
    Prolylrapamycin
  • HY-135459
    LY-289612 148314-61-8 98%
    LY-289612 is a HIV-1 protease inhibitor, with an IC50 of 1.5 nM.
    LY-289612
  • HY-135477
    RWJ-60475 204130-08-5 98%
    RWJ-60475 is a cell-permeable tyrosine phosphatase inhibitor with an IC50 of 3.3 μM. RWJ-60475, by inhibiting the activity of CD45/CD148 phosphatase, interferes with the phagocytic function of macrophages, thereby blocking the invasion of Legionella pneumophila into host cells and the transport of effector proteins. RWJ-60475 significantly reduces the uptake of bacterial particles by macrophages. RWJ-60475 can be used in the research of anti-infection targeting host factors.
    RWJ-60475
  • HY-135480
    Geninthiocin 158792-27-9 98%
    Geninthiocin is a thiopeptide with antibacterial and antifungal activities. Geninthiocin is a tipA promoter.
    Geninthiocin
  • HY-13553R
    Anidulafungin (Standard) 166663-25-8
    Anidulafungin (Standard) is the analytical standard of Anidulafungin. This product is intended for research and analytical applications. Anidulafungin is a new semisynthetic echinocandin with antifungal potency.
    Anidulafungin (Standard)
  • HY-135577
    β-Apooxytetracycline 18751-99-0 99.0%
    β-Apooxytetracycline is a degradation product of Oxytetracycline (HY-B0275). Oxytetracycline is a widespread antibiotic.
    β-Apooxytetracycline
  • HY-135599
    Lysine hydroxamate 25125-92-2 98%
    Lysine hydroxamate is an amino acid hydroxamate that inhibits the growth of Escherichia coli K-12. Of the other amino acid hydroxamates tested, only L-lysine hydroxamate reduced the growth rate. The inhibition of growth by L-serine hydroxamate could be rapidly reversed by adding L-serine to the bacterial culture or by removing the analog by filtration. This reversal was specific for L-serine. L-alanine, glycine, or adenine had no effect on the inhibited culture. There was no evidence for active transport of the analog.
    Lysine hydroxamate
  • HY-135625
    BPH-1218 1426824-36-3 98%
    BPH-1218 is an inhibitor of squalene synthase (SQS), with the IC50 of 31 nM and 64 nM for TcSQS and HsSQS, respectively, that can be used as an anti-infective agent.
    BPH-1218
  • HY-135662
    DHODH-IN-34 1644156-93-3 98%
    DHODH-IN-34 (Compound 21q) is a potent human dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 value of 13 nM. DHODH-IN-34 is promising for research of RNA viruses such as measles virus and chikungunya virus.
    DHODH-IN-34
  • HY-135713
    Penoxsulam 219714-96-2 98%
    Penoxsulam is an acetolactate synthase (ALS) inhibitor herbicide. Penoxsulam inhibits Candida auris acetohydroxyacid synthase (AHAS) with a Ki value of <32 nM. Penoxsulam can be used for postemergence control of annual grasses, sedges, and broadleaf weeds in rice culture. Penoxsulam can be used for the study of Candida auris infections.
    Penoxsulam
  • HY-13573R
    Biapenem (Standard) 120410-24-4 98%
    Biapenem (Standard) is the analytical standard of Biapenem. This product is intended for research and analytical applications. Biapenem (CLI 86815; L 627; LJC 10627) a parenteral carbapenem antibacterial agent with a broad spectrum.
    Biapenem (Standard)
  • HY-13578R
    Brivudine (Standard) 69304-47-8 99.92%
    Brivudine (Standard) is the analytical standard of Brivudine. This product is intended for research and analytical applications. Brivudine is a thymidine analogue with antiviral activity, indicated for the early treatment of acute herpes zoster.
    Brivudine (Standard)
  • HY-13578S
    Brivudine-13C, 15N2 98%
    Brivudine-13C, 15N2 (Bromovinyldeoxyuridine-13C, 15N2) is 13C and 15N labeled Brivudine. Brivudine is a thymidine analogue with antiviral activity, indicated for the early treatment of acute herpes zoster.
    Brivudine-13C, 15N2
  • HY-135862
    Tetraniliprole 1229654-66-3 98%
    Tetraniliprole is an insecticide that can be used in the study of tobacco cutworms (TCW).
    Tetraniliprole
  • HY-13588R
    Cefsulodin sodium (Standard) 52152-93-9
    Cefsulodin (sodium) (Standard) is the analytical standard of Cefsulodin (sodium). This product is intended for research and analytical applications. Cefsulodin (SCE-129) sodium is a third generation β lactam antibiotic and member of the cephems subgroup of antibiotics. Cefsulodin sodium inhibits cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) cross-linking and transpeptidation of peptidogly. Cefsulodin sodium is a potent tyrosine phosphatase inhibitor against mPTPB, a virulent phosphatase from Mycobacterium tuberculosis, with an IC50 value of 16 μM.
    Cefsulodin sodium (Standard)
  • HY-136081
    Hexamidine 3811-75-4 98%
    Hexamidine has amoebicidal effect that can be used for the research of Acanthamoeba keratitis.
    Hexamidine
Cat. No. Product Name / Synonyms Application Reactivity