Geninthiocin
Geninthiocin is a thiopeptide with antibacterial and antifungal activities. Geninthiocin is a tipA promoter.
For research use only. We do not sell to patients.
- CAS No.: 158792-27-9
- Formula: C50H49N15O15S
- Molecular Weight:1132.08
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Geninthiocin is active against a variety of Gram-positive bacteria (MICs = 0.2-4 µg/mL), the Gram-negative bacterium C. violaceum (MIC = 19 µg/mL), and the fungus M. hiemalis (MIC = 38 µg/mL)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 158792-27-9
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Molecular Weight 1132.08
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Formula C50H49N15O15S
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SMILES
NC(C(NC(C(NC(C1=CC=C(C2=NC(C(N[C@@](C(N/C(C3=NC(C(NC(C(N[C@H](C(NC(C4=NC(C(NC(C(NC(C5=NC6=CO5)=C)=O)=C)=O)=C(O4)C)=C)=O)C(C)(O)C)=O)=C)=O)=CO3)=C\C)=O)([H])[C@H](O)C)=O)=CS2)C6=N1)=O)=C)=O)=C)=O
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Structure Classification
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Initial Source
Streptomyces sp
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Appadurai Muthamil Iniyan, et al. Ala-geninthiocin, a new broad spectrum thiopeptide antibiotic, produced by a marine Streptomyces sp. ICN19. J Antibiot (Tokyo). 2019 Feb;72(2):99-105. [Content Brief]
[2]. B S Yun, et al. Microbial metabolites with tipA promoter inducing activity. II. Geninthiocin, a novel thiopeptide produced by Streptomyces sp. DD84. J Antibiot (Tokyo). 1994 Sep;47(9):969-75. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Geninthiocin Related Classifications
HY-135480 Related Classifications
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