Nidulin
Nidulin (Methylustin) is a depsidone isolated from a marine fungus Aspergillus unguis. Nidulin shows antifungal and antibacterial against pathogenetic strains, Pseudomonas aeruginosa, Methicillin-resistant Staphylococcus aureus and Candida albicans with inhibition zones of 9.5 mm, 9.0 mm and 9.0 mm, respectively. Nidulin exhibits potent larvicidality against brine shrimp.
For research use only. We do not sell to patients.
- CAS No.: 10089-10-8
- Formula: C20H17Cl3O5
- Molecular Weight:443.70
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Vero | IC50 |
4.6 μg/mL
Compound: 12
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Cytotoxicity against African green monkey Vero cells by colorimetric assay
Cytotoxicity against African green monkey Vero cells by colorimetric assay
|
[PMID: 33861594] |
| Vero | IC50 |
57 μg/mL
Compound: 12
|
Cytotoxicity against African green monkey Vero cells incubated for 24 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells incubated for 24 hrs by MTT assay
|
[PMID: 33861594] |
Chemical Information
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CAS No. 10089-10-8
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Molecular Weight 443.70
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Formula C20H17Cl3O5
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SMILES
O=C1C2=C(C)C(Cl)=C(O)C(Cl)=C2OC3=C(/C(C)=C/C)C(Cl)=C(OC)C(C)=C3O1
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Synonyms
Methylustin
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Structure Classification
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Initial Source
Aspergillus unguis
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)