2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N12877
    Ophiobolin H 90108-64-8 98%
    Ophiobolin H is a fungal metabolite that can be isolated from Aspergillus ustus. Ophiobolin H inhibits growth of Bacillus subtilis cultures. Ophiobolin H induces hyperacusia in day-old chicks at rates up to 375 mg/kg.
    Ophiobolin H
  • HY-N12893
    Sclerodione 104855-19-8 98%
    Sclerodione is a metabolite that can be produced by the Scleroderris canker fungus, Gremmeniellaabietina. Sclerodione has antifungal activity. Sclerodione is a lipase inhibitor (IC50: 1 μM).
    Sclerodione
  • HY-N12905
    Celastramycin A (isomer) 491600-94-3 98%
    Celastramycin A isomer is an isomer of Celastramycin A (HY-122292), an antibiotic against Gram-negative bacteria and Mycobacterium tuberculosis with an MIC of 0.05-3.1 μg/mL. Celastramycin A exerts immunosuppressive effects in Drosophila ex vivo via the immunodeficiency pathway (IC50 of 8 ng/mL), inhibits human innate immune responses via the TNF-α pathway, and inhibits IL-8 production in HUEVC with an IC50 of 60 ng/mL.
    Celastramycin A (isomer)
  • HY-N12906
    Pyrrocidine A 428439-24-1 98%
    Pyrrocidine A is an antibiotic with antibacterial activity that can be isolated fromLL-Cyan426.
    Pyrrocidine A
  • HY-N12913
    Antibiotic WB 247919-66-0 98%
    Antibiotic WB is an antibioticwith antifungal activity and can be isolated from the soil fungus strain 38.
    Antibiotic WB
  • HY-N12918
    Lewis X tetrasaccharide 23425-36-7 98%
    Lewis X tetrasaccharide is a cell surface glycan that can be used for diagnosis of microbial infections.
    Lewis X tetrasaccharide
  • HY-N12954
    (R)-Mucronulatol 57128-11-7 98%
    (R)-Mucronulatol is a flavonoid that can be isolated from Astragalus adsurgens. (R)-Mucronulatol shows antibacterial activity against Escherichia coli, Bacillus cereus, Staphylococcus aureus, Erwinia carotovora and Bacillus subtili, with MICs of 15.5, 15.5, 7.8, 7.8, 15.5 μg/mL respectively.
    (R)-Mucronulatol
  • HY-N13019
    Elmycin D 169107-03-3 98%
    Elmycin D is an antibiotic, which can be isolated from Streptomyces cellulosae ssp. griseoincarnatus.
    Elmycin D
  • HY-N13024
    Radulone A 221374-79-4 98%
    Radulone A is a secondary metabolite, which can be isolated from the wood decomposing fungus Granulobasidium vellereum. Radulone A inhibits spore germination of Phlebiopsis gigantea, Coniophora puteana and Heterobasidion occidentale, with concentrations of 10 µM, 500 µM and 100 µM, respectively.
    Radulone A
  • HY-N13025
    8-Acetylverrucarin L 77101-88-3 98%
    8-Acetylverrucarin L (Verrucarin L acetate) is a mycotoxin, which exhibits antitumor and antimicrobial activities. 8-Acetylverrucarin L exhibits cytotoxicity to cancer cells HCT116 and A2780S, with IC100 of 9.77 and 9.77 ng/mL. 8-Acetylverrucarin L exhibits antifungal activity against Saccharomyces cerevisiae, Candida albicans and Geotrichum candidum.
    8-Acetylverrucarin L
  • HY-N13034
    Diuvaretin 61463-04-5 98%
    Diuvaretin is an antimalarial agent and a C-phenylated dihydrochalcone. Diuvaretin can be isolated from the roots of U. acuminata. Diuvaretin increases the activity of Caspase-3 and triggers Apoptosis. Diuvaretin exhibits antiparasitic activity against Plasmodium falciparum. Diuvaretin can be used in the research of promyelocytic leukemia and malaria.
    Diuvaretin
  • HY-N13047
    Ningnanmycin 156410-09-2 98%
    Ningnanmycin is a plant antiviral agent. Ningnanmycin binds to specific residues on the TMV CP disc, inhibits CP assembly, disassembles the CP disc into monomers, and disrupts the structure of the TMV CP disc to reduce pathogenicity. Ningnanmycin binds to key amino acids of PVY CP, interferes with CP-CP interactions, inhibits CP assembly and virion formation, and blocks PVY replication. Ningnanmycin induces the expression of antiviral response genes PRXIIB, PRXIIE, PUB4 and PER42, thereby activating the host defense system. Ningnanmycin can be used in studies related to Tobacco Mosaic Virus infection and Potato Virus Y infection.
    Ningnanmycin
  • HY-N13069
    2-Deoxy-20-hydroxyecdysone-22-phosphate 86577-96-0 98%
    2-Deoxy-20-hydroxyecdysone-22-phosphate is an inactive storage form of insect ecdysteroids. 2-Deoxy-20-hydroxyecdysone-22-phosphate exists in newly laid eggs of the desert locust Schistocerca gregaria. 2-Deoxy-20-hydroxyecdysone-22-phosphate can be enzymatically hydrolyzed by embryonic tissues to release the ecdysteroid 2-deoxy-20-hydroxyecdysone (HY-N17267).
    2-Deoxy-20-hydroxyecdysone-22-phosphate
  • HY-N13075
    Mycoplanecin A 72993-51-2 98%
    Mycoplanecin A is a cyclic peptide antibiotic. Mycoplanecin A has strong anti-mycobacterial, luteus, and Hypococcus activity. Mycoplanecin A also has moderate anti-Xanthomonas oryzae activity. Mycoplanecin A also has antibacterial effect on some strains of Actinomycetes.
    Mycoplanecin A
  • HY-N1312R
    Sinapaldehyde (Standard) 4206-58-0
    Sinapaldehyde is a methoxyphenol and a selective COX-2 inhibitor (IC50: 47.8 µM) that can be extracted from various plants. Sinapaldehyde has antibacterial, anti-inflammatory, and antioxidant activities. Sinapaldehyde can scavenge DPPH free radicals (IC50: 172 μM). Sinapaldehyde is active against both Gram-negative and Gram-positive bacteria.
    Sinapaldehyde (Standard)
  • HY-N13149
    Tetromycin C1 205433-82-5 98%
    Tetromycin C1 is an antibiotic bactericide isolated from Streptomyces sp..
    Tetromycin C1
  • HY-N13150
    Norvancomycin 91700-98-0 98%
    N-Demethylvancomycin is a glycopeptide antibiotic which can be extracted from Nocardia orientalis and active against several strains of S. aureus and S. epidermidis. N-Demethylvancomycin can be used for infection research.
    Norvancomycin
  • HY-N13151
    3-GlcA-28-AraRhaxyl-medicagenate 128192-15-4 98%
    3-GlcA-28-AraRhaxyl-medicagenate is an insect toxin belonging to the saponin family. 3-GlcA-28-AraRhaxyl-medicagenate exhibits antifungal activity and causes mortality in rice weevils at doses down to 0.1 mg/mL.
    3-GlcA-28-AraRhaxyl-medicagenate
  • HY-N13156
    Amycolatopsin B 2209112-97-8 98%
    Amycolatopsin B (compound 2) is a glycosylated polyketide macrolide with antifungal activity that was isolated from the soil isolate Amycolatopsis sp. MST-108494.
    Amycolatopsin B
  • HY-N13186
    δ-(E)-Deoxy-amplexichromanol 1639050-37-5 98%
    δ-(E)-Deoxy-amplexichromanol is a δ-tocotrienolic acid derivative with potent antibacterial activities, which is derivated from hydromethanolic extract of the cones of C. atlantica.
    δ-(E)-Deoxy-amplexichromanol
Cat. No. Product Name / Synonyms Application Reactivity