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Cat. No.: HY-N12893

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Sclerodione

Sclerodione is a metabolite that can be produced by the Scleroderris canker fungus, Gremmeniellaabietina. Sclerodione has antifungal activity. Sclerodione is a lipase inhibitor (IC₅₀: 1 μM).

For research use only. We do not sell to patients.

CAS No.: 104855-19-8
Formula: C₁₈H₁₆O₅
Molecular Weight:312.32

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Sclerodione Chemical Structure

CAS No.: 104855-19-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 104855-19-8
Molecular Weight 312.32
Formula C₁₈H₁₆O₅
SMILES

CC(C1=C2C(C3=O)=C(C4=C1O[C@H](C4(C)C)C)O)=CC(O)=C2C3=O
Structure Classification
- Antibiotics
- Other Antibiotics
Initial Source
- Microorganisms
Gremmeniella abietina.
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. William A. et al. Metabolites produced by the Scleroderris canker fungus, Gremmeniellaabietina. Part 1. Canadian Journal of Chemistry. 1986. 64(8): 1585-1589.

[2]. Hidayat Hussain, et al. Phytochemical investigation and antimicrobial activity of an endophytic fungus Phoma sp.Journal of King Saud University - Science. Volume 27, Issue 1, January 2015, Pages 92-95.

[3]. Macabeo APG, et al. Alpha-Glucosidase- and Lipase-Inhibitory Phenalenones from a New Species of Pseudolophiostoma Originating from Thailand. Molecules. 2020 Feb 20;25(4):965. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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