104855-19-8
104855-19-8
Chemical Structure
Sclerodione
- CAS. Nr.: 104855-19-8
- Formula:C18H16O5
- Molecular Weight:312.32
InChIKey: NHLBJUZHBDCHJJ-ZETCQYMHSA-N
SMILES: CC(C1=C2C(C3=O)=C(C4=C1O[C@H](C4(C)C)C)O)=CC(O)=C2C3=O
Biological Activity: Sclerodione is a metabolite that can be produced by the Scleroderris canker fungus, Gremmeniellaabietina. Sclerodione has antifungal activity. Sclerodione is a lipase inhibitor (IC50: 1 μM)[1][2][3].
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Sclerodione | Sclerodione is a metabolite that can be produced by the Scleroderris canker fungus, Gremmeniellaabietina. Sclerodione has antifungal activity. Sclerodione is a lipase inhibitor (IC50: 1 μM). | |||||||||||||||||||||
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References
- [1]. William A. et al. Metabolites produced by the Scleroderris canker fungus, Gremmeniellaabietina. Part 1. Canadian Journal of Chemistry. 1986. 64(8): 1585-1589.
- [2]. Hidayat Hussain, et al. Phytochemical investigation and antimicrobial activity of an endophytic fungus Phoma sp.Journal of King Saud University - Science. Volume 27, Issue 1, January 2015, Pages 92-95.
- [3]. Macabeo APG, et al. Alpha-Glucosidase- and Lipase-Inhibitory Phenalenones from a New Species of Pseudolophiostoma Originating from Thailand. Molecules. 2020 Feb 20;25(4):965. [Content Brief]
Keywords
