2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N7252R
    Daphnin (Standard) 486-55-5
    Daphnin (Standard) is the analytical standard of Daphnin. This product is intended for research and analytical applications. Daphnin is one of the major coumarin bioactive components with antibacterial activity. Daphnin is isolated from the whole herb of Daphne odora (Thunb.), which is a folk medicine in China for the relief of fever.
    Daphnin (Standard)
  • HY-N7423A
    (E)-Methyl isoferulate 97966-29-5 98%
    (E)-Methyl isoferulate ((E)-Isoferulic acid methyl ester) is a derivative of Cinnamic acid (HY-N0610A) and NO inhibitor, with an IC50 > 100 μM against nitric oxide production. (E)-Methyl isoferulate is isolable from the solid cultures of the edible mushroom Neolentinus lepideus. (E)-Methyl isoferulate exerts mild anticancer effects against liver cancer and leukemia.
    (E)-Methyl isoferulate
  • HY-N7503R
    Psoralenoside (Standard) 905954-17-8 98%
    Psoralenoside is a benzofuran glycoside from Psoralea corylifolia. Psoralenoside exhibits high binding affinities against histaminergic H1, calmodulin, and voltage-gated L-type calcium channels (E-value≥-6.5 Kcal/mol). Psoralenoside shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity.
    Psoralenoside (Standard)
  • HY-N7515A
    (E)-Pinocembrin chalcone 82451-30-7 98%
    (E)-Pinocembrin chalcone is an antibacterial compound that can be isolated from Helichrysum trilineatum.
    (E)-Pinocembrin chalcone
  • HY-N7619R
    Xanthopurpurin (Standard) 518-83-2 98%
    Xanthopurpurin is an orally active anthraquinone glycoside. Xanthopurpurin can be isolated from the rhizome of Rubia akane. Xanthopurpurin has antiviral effects against rotavirus and HIV. Xanthopurpurin has a strong inhibitory effect on collagen-induced platelet aggregation. Xanthopurpurin prevents peanut allergy.
    Xanthopurpurin (Standard)
  • HY-N7648A
    Atherosperminine hydrochloride 54749-97-2 98%
    Atherosperminine (Atherospermine) hydrochloride is a phosphodiesterase inhibitor. Atherosperminine hydrochloride inhibits growth of chloroquine-resistant Plasmodium falciparum. Atherosperminine hydrochloride scavenges DPPH free radicals, exhibits ferric reducing power, and chelates metal ions. Atherosperminine hydrochloride can be used for the research of malaria.
    Atherosperminine hydrochloride
  • HY-N7926R
    Pentadecane (Standard) 629-62-9 98%
    Pentadecane (Standard) is the analytical standard of Pentadecane (HY-N7926). This product is intended for research and analytical applications. Pentadecane is an orally active natural plant volatile alkane with anti-inflammatory, analgesic, antipyretic and anti-leishmanial activities. Pentadecane presents IC50 values of 65.3 μM, 60.5 μM and 194.8 μM against Leishmania infantum promastigotes, amastigotes and intracellular amastigotes, respectively. Pentadecane downregulates the mRNA expression of TNF-α and IL-12 and inhibits the release of inflammatory mediators. Pentadecane arrests the cell cycle of Leishmania infantum and induces apoptosis. Pentadecane can be applied to the research of inflammation and leishmaniasis.
    Pentadecane (Standard)
  • HY-N8393R
    Ascr#18 (Standard) 1355681-10-5 98%
    Ascr#18 (Standard) is the analytical standard of Ascr#18 (HY-N8393). This product is intended for research and analytical applications. Ascr#18, an ascaroside, is a hormone of nematodes. Ascr#18 is expressed during nematode development. Ascr#18 increases resistance in Arabidopsis, tomato, potato and barley to viral, bacterial, oomycete, fungal and nematode infections.
    Ascr#18 (Standard)
  • HY-N8432R
    Dipyrithione (Standard) 3696-28-4 98%
    Dipyrithione (Standard) is the analytical standard of Dipyrithione (HY-N8432). This product is intended for research and analytical applications. Dipyrithione is a potent antimicrobial agent. Dipyrithione shows antifungal activity and antiproliferative activity. Dipyrithione induces apoptosis and cycle arrest at G1 phase. Dipyrithione shows anti-inflammatory activity in vivo. Dipyrithione shows anti-tumor activity. Dipyrithione has the potential for the research of dermatophytosis.
    Dipyrithione (Standard)
  • HY-N8443S
    Isoaltenuene-d6 98%
    Isoaltenuene-d6 is deuterium labeled Isoaltenuene. Isoaltenuene is an anti-bacterial agent with moderate activity against Staphylococcus aureus. Isoaltenuene can be isolated from fungus Alternaria alternate cib-137.
    Isoaltenuene-d6
  • HY-N9388R
    Andrograpanin (Standard) 82209-74-3
    Andrograpanin (Standard) is the analytical standard of Andrograpanin. This product is intended for research and analytical applications. Andrograpanin, a bioactive compound from Andrographis paniculata, exhibits anti-inflammatory and anti-infectious properties.
    Andrograpanin (Standard)
  • HY-N9499R
    3-Methoxyflavone (Standard) 7245-02-5 98%
    3-Methoxyflavone (Standard) is the analytical standard of 3-Methoxyflavone. This product is intended for research and analytical applications. 3-Methoxyflavone is a flavonoid compound isolated from Artemisia incanescens with antiviral activity[1][2].
    3-Methoxyflavone (Standard)
  • HY-N9947A
    (rac)-Methyl-6-gingerol 61914-52-1 98%
    (rac)-Methyl-6-gingerol (Compound 14) is the racemate of Methyl-6-gingerol (HY-N9947). Methyl-6-gingerol is an antibiotic that can be isolated from Aframomum melegueta. Methyl-6-gingerol exhibits anti-mycobacterial activity by inhibiting the efflux of toxins within Mycobacterium species.
    (rac)-Methyl-6-gingerol
  • HY-P10200
    CP7-FP13-2 3032621-32-9 98%
    CP7-FP13-2 is a peptide with antivirulence factor and antibacterial activity. CP7-FP13-2 inhibits the formation of Staphylococcus aureus biofilm and has good antibacterial efficacy in mice.
    CP7-FP13-2
  • HY-P10559
    (RXR)4XB 879010-15-8 98%
    (RXR)4XB is a cell-penetrating peptide, that binds the phosphorodiamidate morpholino oligomers (PMOs), forms peptide-conjugated PMOs (PPMOs), and improves the delivery of PMO into bacterial cells. (RXR)4XB-PMO conjugate prevents the formation of biofilms, inhibits Pseudomonas aeruginosa with MIC50 of 0.5 to 16 μM, and reduces the bacterial burden in mouse acute pneumonia models.
    (RXR)4XB
  • HY-P10657
    Ac-DEMEEC-OH 208921-05-5 98%
    Ac-DEMEEC-OH is a HCV NS3 protease competitive inhibitor (Ki: 0.6 µM).
    Ac-DEMEEC-OH
  • HY-P10668
    Ac-EVKKQR-pNA 410532-54-6 98%
    Ac-EVKKQR-pNA is a competitive chromogenic para-nitroanilide substrate corresponding to the P6-P1 segment amino-terminal to the NS2B-NS3 cleavage site but with a more reactive, hydrolytically cleavable, para-nitroanilide at the P1’ position. Ac-EVKKQR-pNA is promising for research of dengue 2 virus and flavivirus virus infection.
    Ac-EVKKQR-pNA
  • HY-P10916
    Micafungin metabolite M1 539823-80-8 98%
    Micafungin metabolite M1 is an active metabolite of Micafungin (HY-17579), which is metabolized by arylsulfatase and exhibits antifungal activity. Micafungin metabolite M1 can be used for research on deep fungal infections caused by Candida and Aspergillus species.
    Micafungin metabolite M1
  • HY-P11546
    Antiviral agent 76 1612249-42-9
    Antiviral agent 76 is an antiviral peptide containing azide groups, which has anti-hepatitis C virus (HCV) activity.
    Antiviral agent 76
  • HY-P11634
    KF-22 98%
    KF-22 is an antimicrobial peptide that exhibits antimicrobial activity against both Gram-negative and Gram-positive bacteria. KF-22 demonstrates broad-spectrum, potent activity against multidrug-resistant bacteria with low toxicity. KF-22 can be used in research related to infections.
    KF-22
Cat. No. Product Name / Synonyms Application Reactivity