(RXR)4XB
(RXR)4XB is a cell-penetrating peptide, that binds the phosphorodiamidate morpholino oligomers (PMOs), forms peptide-conjugated PMOs (PPMOs), and improves the delivery of PMO into bacterial cells. (RXR)4XB-PMO conjugate prevents the formation of biofilms, inhibits Pseudomonas aeruginosa with MIC50 of 0.5 to 16 μM, and reduces the bacterial burden in mouse acute pneumonia models.
For research use only. We do not sell to patients.
- CAS No.: 879010-15-8
- Formula: C81H158N38O15
- Molecular Weight:1904.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 879010-15-8
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Molecular Weight 1904.37
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Formula C81H158N38O15
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Sequence
Arg-{Ahx}-Arg-Arg-{Ahx}-Arg-Arg-{Ahx}-Arg-Arg-{Ahx}-Arg-{Ahx-βAla}
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Sequence Shortening
R-{Ahx}-RR-{Ahx}-RR-{Ahx}-RR-{Ahx}-R-{Ahx-βAla}
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)