Search Result

Results for "

cell-penetrating

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (4) Aminopeptidase (1) Apoptosis (4) Autophagy (2) Bacterial (3) Caspase (1) Cathepsin (1) CXCR (3) Endogenous Metabolite (2) ERK (3) FABP (1) Fluorescent Dye (3) Glucosidase (1) GnRH Receptor (1) Guanylate Cyclase (1) HIV (16) iGluR (3) Influenza Virus (1) Integrin (6) Interleukin Related (1) JNK (3) MEK (1) MMP (1) MyD88 (1) nAChR (1) Neuropeptide Y Receptor (1) NF-κB (4) NO Synthase (2) Nuclear Factor of activated T Cells (NFAT) (3) PI3K (2) Pim (1) PKC (5) Protease Activated Receptor (PAR) (5) RABV (3) Somatostatin Receptor (1) Src (1) Transferrin Receptor (3) VEGFR (1)
By Research Areas:	Cancer (48) Cardiovascular Disease (8) Endocrinology (2) Infection (21) Inflammation/Immunology (23) Metabolic Disease (9) Neurological Disease (18)

By Targets:

Amino Acid Derivatives (4)

Aminopeptidase (1)

Apoptosis (4)

Autophagy (2)

Bacterial (3)

Caspase (1)

Cathepsin (1)

CXCR (3)

Endogenous Metabolite (2)

ERK (3)

FABP (1)

Fluorescent Dye (3)

Glucosidase (1)

GnRH Receptor (1)

Guanylate Cyclase (1)

HIV (16)

iGluR (3)

Influenza Virus (1)

Integrin (6)

Interleukin Related (1)

JNK (3)

MEK (1)

MMP (1)

MyD88 (1)

nAChR (1)

Neuropeptide Y Receptor (1)

NF-κB (4)

NO Synthase (2)

Nuclear Factor of activated T Cells (NFAT) (3)

PI3K (2)

Pim (1)

PKC (5)

Protease Activated Receptor (PAR) (5)

RABV (3)

Somatostatin Receptor (1)

Src (1)

Transferrin Receptor (3)

VEGFR (1)

By Research Areas:

Cancer (48)

Cardiovascular Disease (8)

Endocrinology (2)

Infection (21)

Inflammation/Immunology (23)

Metabolic Disease (9)

Neurological Disease (18)

Inhibitors & Agonists

175

Peptides

Inhibitory Antibodies

Natural
Products

Cys-Penetratin	Amino Acid Derivatives	Others
Cys-Penetratin is a cell-penetrating peptide (CPP) with sequence of CRQIKIWFQNRRMKWKK .

TAT (47-57), TAMRA-labeled	Amino Acid Derivatives	Others
TAT (47-57), TAMRA-labeled is a TAMRA-labeled peptide with cell-penetrating activity.

Parstatin(mouse)	Protease Activated Receptor (PAR)	Cardiovascular Disease Inflammation/Immunology
Parstatin(mouse), a cell-penetrating PAR-1 thrombin receptor agonist peptide, is a potent inhibitor of angiogenesis .

Parstatin(human)	Protease Activated Receptor (PAR)	Cardiovascular Disease Inflammation/Immunology
Parstatin(human), a cell-penetrating PAR-1 thrombin receptor agonist peptide, is a potent inhibitor of angiogenesis .

Cys(Npys)-TAT (47-57), FAM-labeled	Amino Acid Derivatives	Others
Cys(Npys)-TAT (47-57), FAM-labeled is a Cys(Npys)-activated cell-penetrating peptide with FAM-labeled .

Parstatin(human) TFA	Protease Activated Receptor (PAR)	Cardiovascular Disease Inflammation/Immunology
Parstatin(human) TFA, a cell-penetrating PAR-1 thrombin receptor agonist peptide, is a potent inhibitor of angiogenesis .

Parstatin(mouse) TFA	Protease Activated Receptor (PAR)	Cardiovascular Disease Inflammation/Immunology
Parstatin(mouse) TFA, a cell-penetrating PAR-1 thrombin receptor agonist peptide, is a potent inhibitor of angiogenesis .

TAT (47-57), FAM-labeled	HIV	Others
TAT (47-57), FAM-labeled is a cell-penetrating peptide (CPP). TAT (47-57), FAM-labeled has the potential for intracellular drug delivery research .

FITC-LC-TAT (47-57)	HIV	Others
FITC-LC-TAT (47-57) is a FITC labeled TAT peptide. TAT is a cell-penetrating peptide (CPP). TAT can increase the yields and the solubility of heterologous proteins .

TAT (47-57) GGG-Cys(Npys)	HIV	Others
TAT (47-57) GGG-Cys(Npys) is a cell-penetrating peptide (CPP). TAT (47-57) GGG-Cys(Npys) has the potential for intracellular drug delivery research .

TAT TFA	HIV	Infection
TAT TFA (YGRKKRRQRRR) is derived from the transactivator of transcription (TAT) of human immunodeficiency virus (HIV-1) and is a cell-penetrating peptide. TAT can increase the yields and the solubility of heterologous proteins .

TAT	HIV	Infection
TAT (YGRKKRRQRRR) is derived from the transactivator of transcription (TAT) of human immunodeficiency virus-1 (HIV-1) and is a cell-penetrating peptide. TAT can increase the yields and the solubility of heterologous proteins .

HIV-1 TAT (48-60)	HIV	Infection
HIV-1 TAT (48-60) is a cell-penetrating peptide derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. It has been used to deliver exogenous macromolecules into cells in a non-disruptive way.

TAT-HA2 Fusion Peptide	Influenza Virus	Others
TAT-HA2 Fusion Peptide is a peptide-based delivery agent that combines the pH-sensitive HA2 fusion peptide from Influenza and the cell-penetrating peptide TAT from HIV. TAT-HA2 Fusion Peptide induces the cellular uptake of macromolecules into endosomes via the TAT moiety and to respond to the acidifying lumen of endosomes to cause membrane leakage and release of macromolecules into cells via the HA2 moiety .

PZ-128 P1pal-7	Protease Activated Receptor (PAR)	Cardiovascular Disease Cancer
PZ-128 (P1pal-7), a cell-penetrating lipopeptide pepducin, is a first-in-class, specific and reversible protease-activated receptor-1 (PAR1) antagonist. PZ-128 targets the cytoplasmic surface of PAR1 and interrupts signaling to internally-located G (PAR1-G) proteins. PZ-128 has antiplatelet, anti-metastatic, anti-angiogenic and anticancer effects .

Protein LMWP	VEGFR	Cancer
Protein LMWP is a cell-penetrating peptide with vascular endothelial growth factor (VEGF) inhibitory activity. Protein LMWP can inhibit tumor growth and is used in cancer research .

NRPSs-IN-1	Others	Infection
NRPSs-IN-1 (Compound 7) is a cell-penetrating inhibitor of non-ribosomal peptide synthetase (NRPSs). NRPSs-IN-1 K inhibits gramicidin S synthetase A (GrsA) with a K_d value of 16.6 nM .

TLR1 3 Publications Verification	MyD88	Inflammation/Immunology
TLR1 (compound 4a) is a low molecular weight, cell-penetrating Toll/IL-1 receptor/resistance (TIR) domain/BB-Loop mimic. TLR1 inhibits IL-1 receptor-mediated responses .

TAT peptide	HIV	Infection
TAT peptide is a cell penetrating peptide (GRKKRRQRRRPQ) derived from the trans-activating transcriptional activator (Tat) from HIV-1 .

TAT peptide TFA	HIV	Infection
TAT peptide (TFA) is a cell penetrating peptide (GRKKRRQRRRPQ) derived from the trans-activating transcriptional activator (Tat) from HIV-1 .

Cys-TAT(47-57) Cys-[HIV-Tat (47-57)]	HIV	Infection
Cys-TAT(47-57) (Cys-[HIV-Tat (47-57)]) is an arginine rich cell penetrating peptide derived from the HIV-1 transactivating protein.

Cys-TAT(47-57) TFA Cys-[HIV-Tat (47-57)] TFA	HIV	Infection
Cys-TAT(47-57) (Cys-[HIV-Tat (47-57)]) is an arginine rich cell penetrating peptide derived from the HIV-1 transactivating protein.

Rabies Virus Glycoprotein	RABV	Infection
Rabies Virus Glycoprotein is a 29-amino-acid cell penetrating peptide derived from a rabies virus glycoprotein that can cross the blood-brain barrier (BBB) and enter brain cells.

Rabies Virus Glycoprotein TFA 1 Publications Verification	RABV	Infection
Rabies Virus Glycoprotein (TFA) is a 29-amino-acid cell penetrating peptide derived from a rabies virus glycoprotein that can cross the blood-brain barrier (BBB) and enter brain cells .

TAT-MEK1	ERK	Inflammation/Immunology
TAT-MEK1 is an inhibitor ofERK2, consisting of TAT and MEK1 (N-terminal), TAT (YGRKKRRQRRR) derived from human immunodeficiency (HIV-1) transcriptional trans activator (TAT), is a cell-penetrating peptide. TAT-MEK1 IC₅₀ in vitro for ERK2 is 29 μM .

JNK-IN-12	JNK	Cancer
JNK-IN-12 (compound P2) is a mitochondrial-targeted JNK inhibitor (IC₅₀=66.3 nM), consisting of a mitochondrial-specific cell-penetrating peptide and a specific inhibitor of JNK, SP600125 (HY-12041). JNK-IN-12 doesn't inhibit nuclear JNK signaling, but does inhibit mitochondrial JNK phosphorylation. JNK-IN-12 helps to improve the Parkinson's disease (PD) both in vitro and in vivo .

Clervonafusp alfa VAL-1221	Glucosidase	Others
Clervonafusp alfa (VAL-1221) is a fusion protein targeting both cytosolic and lysosomal glycogen. Clervonafusp alfa is comprised of the Fab portion of a cell-penetrating antibody and recombinant human acid alpha glucosidase (rhGAA), the former utilizing the nucleoside transporter ENT-2 to gain access to the cytosol, and the latter enters lysosomes via mannose-6-phosphate receptors (M6PRs). Clervonafusp alfa can be used for late-onset Pompe disease research .

Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R)	RABV	Infection
Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R), a chimeric peptide consisting of 29 amino acids, is synthesized by adding nona-arginine motif to the carboxy terminus of RVG (rabies virus glycoprotein). Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R) is positively charged and able to bind negatively charged nucleic acids via charge interaction .

Calpeptin 15+ Cited Publications
Calpeptin is a potent, cell penetrating calpain inhibitor, with an ID₅₀ of 40 nM for Calpain I in human platelets . Calpeptin is also an inhibitor of cathepsin K .

TAT-SAMβA	PKC	Cardiovascular Disease
TAT-SAMβA is the peptide consist of RNAENFDRF (SAMβA; HY-P3429) conjugated to the cell penetrating TAT protein-derived peptide TAT_47–57. TAT-SAMβA is a selective antagonist of Mfn1-βIIPKC association. TAT-SAMβA protects mouse embryonic fibroblast cells (MEFs) against oxidative stress-induced cytotoxicity .

Arg-Gly-Asp-Ser 5 Publications Verification RGDS peptide; Fibronectin tetrapeptide	Integrin	Inflammation/Immunology
Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. Arg-Gly-Asp-Ser directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1.

D-JNKI-1 5 Publications Verification AM-111; XG-102	JNK	Others
D-JNKI-1 (AM-111) is a highly potent and cell-permeable peptide inhibitor of JNK.

SN50 30+ Cited Publications	NF-κB	Inflammation/Immunology
SN50 is a cell permeable inhibitor of NF-κB translocation.

Tuftsin 2 Publications Verification	Endogenous Metabolite	Inflammation/Immunology
Tuftsin is a tetrapeptide. Tuftsin is a macrophage/microglial activator.

Gly-Arg-Gly-Asp-Ser GRGDS	Integrin	Others
Gly-Arg-Gly-Asp-Ser is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin. Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3 and αvβ5 with estimated IC₅₀ of ∼5 and ∼6.5 μM

RGD 5 Publications Verification	Integrin	Cancer
RGD is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.

Tuftsin diacetate	Endogenous Metabolite	Inflammation/Immunology
Tuftsin diacetate, a tetrapeptide, is a macrophage/microglial activator.

NFAT Inhibitor-1 10+ Cited Publications VIVIT peptide	Nuclear Factor of activated T Cells (NFAT)	Inflammation/Immunology
NFAT Inhibitor (VIVIT peptide) is a cell-permeable peptide inhibitor of nuclear factor of activated Tcells (NFAT) that selectively inhibits calcineurin-mediated dephosphorylation of NFAT .

740 Y-P Maximum Cited Publications 126 Publications Verification 740YPDGFR; PDGFR 740Y-P	PI3K Autophagy	Cancer
740 Y-P (740YPDGFR; PDGFR 740Y-P) is a potent and cell-permeable PI3K activator. 740 Y-P readily binds GST fusion proteins containing both the N- and C- terminal SH2 domains of p85 but fails to bind GST alone .

RGD Trifluoroacetate 5 Publications Verification	Integrin	Cancer
RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; RGD Trifluoroacetate binds to integrins.

MPG, HIV related	HIV	Infection
MPG, HIV related is 27-aa peptide, derived from both the nuclear localisation sequence of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41 and is a potent delivery agent for the generalised delivery of nucleic acids and of oligonucleotides into cultured cells.

L-JNKI-1 2 Publications Verification	JNK	Neurological Disease
L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK.

Tat-NR2B9c TFA 5+ Cited Publications Tat-NR2Bct TFA; NA-1 TFA	iGluR NO Synthase	Neurological Disease
Tat-NR2B9c TFA (Tat-NR2Bct TFA) is a postsynaptic density-95 (PSD-95) inhibitor, with EC₅₀ values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c TFA disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC₅₀ values of 0.5 μM and 8 μM, respectively. Tat-NR2B9c TFA also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy .

TAT (48-57) (TFA)	HIV	Infection
TAT (48-57) (TFA) is a cell-permeable peptide, derived from HIV-1 transactivator of transcription (Tat) protein residue 48-57 .

Gly-Arg-Gly-Asp-Ser TFA GRGDS TFA	Integrin	Inflammation/Immunology
Gly-Arg-Gly-Asp-Ser (TFA) is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin . Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3 and αvβ5 with estimated IC₅₀ of ∼5 and ∼6.5 μM .

Arg-Gly-Asp-Ser TFA RGDS peptide TFA; Fibronectin tetrapeptide TFA	Integrin	Inflammation/Immunology
Arg-Gly-Asp-Ser (TFA) is an integrin binding sequence that inhibits integrin receptor function. Arg-Gly-Asp-Ser (TFA) directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1 .

Cat. No.	Product Name	Target	Research Area

HY-P2500

(Arg)9, FAM-labeled	Peptides	Others
(Arg)9, FAM-labeled, a cell-penetrating peptide (CPP), is a nona-arginine (ARG) with FAM label. CPPs have emerged as powerful tools for delivering bioactive cargoes into the cytosol of intact cells .

HY-P10156

MAP17 cell-penetrating peptide MAP17	Peptides	Others
MAP17 (Cell-penetrating peptide MAP17) is a synthetic secondary amphipathic cell-penetrating peptides, with sequence of QLALQLALQALQAALQLA .

HY-P4139

*activable cell-penetrating* peptide (ACCP)**	Peptides	Others
activable cell-penetrating peptide (ACCP) consists of a polycationic CPP (typically arg9 or r9) connected via a cleavable linker to a matching polyanion (typically glu9 or e9), which reduces the net charge to nearly zero and thereby inhibits adhesion and uptake into cells .

HY-P10190

CADY

Peptides Others

CADY is a cell-penetrating peptide (CPPs) peptide with a sequence of GLWRALWRLLRSLWRLLWRA. CADY can be used as a vector tool for intracellular delivery .

HY-P4132

Membrane-Permeable Sequence, MPS	Peptides	Cancer
Membrane-Permeable Sequence, MPS is a cell-penetrating peptide (CPP). Membrane-Permeable Sequence, MPS can be used for the research of membrane crossing mechanism .

HY-P1781A

Peptide C105Y TFA	Peptides	Cancer
Peptide C105Y TFA, a synthetic and cell-penetrating peptide based on the amino acid sequence corresponding to residues 359-374 of α1-antitrypsin, enhances gene expression from DNA nanoparticles .

HY-P0133B

(Arg)9 acetate 1 Publications Verification Nona-L-arginine acetate; Peptide R9 acetate	Peptides	Neurological Disease
(Arg)9 (Nona-L-arginine) acetate is a cell-penetrating peptide (CPP) made up of 9 arginine residues. (Arg)9 acetate has neuroprotective property, exhibits neuroprotective activity with an IC₅₀ of 0.78 μM in the glutamic acid model .

HY-P3432

DfTat	Peptides	Others
DfTat is a dimer of the prototypical cell-penetrating peptide TAT. DfTat can deliver small molecules, peptides and proteins into live cells with a particularly high efficiency. DfTat labeled with the rhodamine can be used as a tracer for easy detection .

HY-P0133A

(Arg)9 TFA Nona-L-arginine TFA; Peptide R9 TFA	Peptides	Neurological Disease
(Arg)9 (Nona-L-arginine) TFA is a cell-penetrating peptide (CPP) made up of 9 arginine residues. (Arg)9 TFA has neuroprotective property, exhibits neuroprotective activity with an IC₅₀ of 0.78 μM in the glutamic acid model .

HY-P1848

Pep-1 (uncapped)

Peptides Cancer

Pep-1 (uncapped) is a cell-penetrating peptide.

HY-P4104

pVEC (Cadherin-5)	Peptides	Others
pVEC (Cadherin-5) is a cell-penetrating 18-amino acid-long peptide derived from the murine sequence of the cell adhesion molecule vascular endothelial cadherin. pVEC (Cadherin-5) is efficiently and rapidly taken up into cells, it can be used as a carrier peptide .

HY-P2193

TAT-amide

Peptides Infection

TAT-amide is a cell penetrating peptide. Cell-penetrating peptides (CPPs) are short amino acid sequences able to enter different cells .
HY-P4093

Cys-Penetratin

Amino Acid Derivatives Others

Cys-Penetratin is a cell-penetrating peptide (CPP) with sequence of CRQIKIWFQNRRMKWKK .
HY-P2193A

TAT-amide TFA

Peptides Infection

TAT-amide TFA is a cell penetrating peptide. Cell-penetrating peptides (CPPs) are short amino acid sequences able to enter different cells .

HY-P0133

(Arg)9 Nona-L-arginine; Peptide R9	Peptides	Neurological Disease
(Arg)9 (Nona-L-arginine) is a cell-penetrating peptide (CPP) made up of 9 arginine residues. (Arg)9 has neuroprotective property, exhibits neuroprotective activity with an IC₅₀ of 0.78 μM in the glutamic acid model .

HY-P4077

Antennapedia Peptide, amide

Penetratin amide
Peptides Others

Antennapedia Peptide, amide is a C-terminal amide cell-penetrating peptide .
HY-P4090

CPP2

Peptides Others

CPP2 is a cell-penetrating peptide, with a high intracellular translocation efficiency .
HY-P4084

KLA seq

Peptides Others

KLA seq is a cell-penetrating α-helical amphipathic model peptide .
HY-P4105

TAT (47-57), TAMRA-labeled

Amino Acid Derivatives Others

TAT (47-57), TAMRA-labeled is a TAMRA-labeled peptide with cell-penetrating activity.
HY-P4134

Lipid Membrane Translocating Peptide

Peptides Others

Lipid Membrane Translocating Peptide is a cell-penetrating peptide consisting of 13 amino acids .

HY-P1261

Parstatin(mouse)	Protease Activated Receptor (PAR)	Cardiovascular Disease Inflammation/Immunology
Parstatin(mouse), a cell-penetrating PAR-1 thrombin receptor agonist peptide, is a potent inhibitor of angiogenesis .

HY-P1262

Parstatin(human)	Protease Activated Receptor (PAR)	Cardiovascular Disease Inflammation/Immunology
Parstatin(human), a cell-penetrating PAR-1 thrombin receptor agonist peptide, is a potent inhibitor of angiogenesis .

HY-P4103

Cys(Npys)-TAT (47-57), FAM-labeled

Amino Acid Derivatives Others

Cys(Npys)-TAT (47-57), FAM-labeled is a Cys(Npys)-activated cell-penetrating peptide with FAM-labeled .

HY-P1262A

Parstatin(human) TFA	Protease Activated Receptor (PAR)	Cardiovascular Disease Inflammation/Immunology
Parstatin(human) TFA, a cell-penetrating PAR-1 thrombin receptor agonist peptide, is a potent inhibitor of angiogenesis .

HY-P1261A

Parstatin(mouse) TFA	Protease Activated Receptor (PAR)	Cardiovascular Disease Inflammation/Immunology
Parstatin(mouse) TFA, a cell-penetrating PAR-1 thrombin receptor agonist peptide, is a potent inhibitor of angiogenesis .

HY-P4081

plsl

Peptides Others

Plsl is a cell-penetrating peptide (CPP), with sequence of RVIRVWFQNKRCKDKK. Plsl, belongs to Penetralia family, and origins from Igl-1 homeodomain .
HY-P4122

TAT (47-57), FAM-labeled

HIV Others

TAT (47-57), FAM-labeled is a cell-penetrating peptide (CPP). TAT (47-57), FAM-labeled has the potential for intracellular drug delivery research .

HY-P4125

FITC-LC-TAT (47-57)	HIV	Others
FITC-LC-TAT (47-57) is a FITC labeled TAT peptide. TAT is a cell-penetrating peptide (CPP). TAT can increase the yields and the solubility of heterologous proteins .

HY-P0307

Antennapedia Peptide Penetratin peptide	Peptides	Cancer
Antennapedia Peptide (Penetratin peptide) is a 16 amino acid peptide, originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia and is a member of the family of cell-penetrating peptides.

HY-P4118

EB1 peptide penetrating analog	Peptides	Others
EB1 peptide (Penetrating analog), a Penetratin peptide derivative, is an amphipathic cell-penetrating peptide (CPP). EB1 peptide has the potential for intracellular drug delivery research .

HY-P4123

TAT (47-57) GGG-Cys(Npys)	HIV	Others
TAT (47-57) GGG-Cys(Npys) is a cell-penetrating peptide (CPP). TAT (47-57) GGG-Cys(Npys) has the potential for intracellular drug delivery research .

HY-P10068

LAH5	Peptides	Others
LAH5 is an amphipathic cell-penetrating peptide. LAH5 effectively delivers CRISPR-Cas9 components into the nuclei of target cells by forming nanocomplexes with both RNP and RNP/HDR cargo .

HY-P0307A

Antennapedia Peptide TFA Penetratin peptide TFA	Peptides	Inflammation/Immunology Cancer
Antennapedia Peptide (Penetratin peptide) TFA is a 16 amino acid peptide, originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia and is a member of the family of cell-penetrating peptides.

HY-P0281A

TAT TFA	HIV	Infection
TAT TFA (YGRKKRRQRRR) is derived from the transactivator of transcription (TAT) of human immunodeficiency virus (HIV-1) and is a cell-penetrating peptide. TAT can increase the yields and the solubility of heterologous proteins .

HY-P10068A

LAH5 TFA	Peptides	Others
LAH5 TFA is an amphipathic cell-penetrating peptide. LAH5 THA effectively delivers CRISPR-Cas9 components into the nuclei of target cells by forming nanocomplexes with both RNP and RNP/HDR cargo .

HY-P0281

TAT	HIV	Infection
TAT (YGRKKRRQRRR) is derived from the transactivator of transcription (TAT) of human immunodeficiency virus-1 (HIV-1) and is a cell-penetrating peptide. TAT can increase the yields and the solubility of heterologous proteins .

HY-P1732

Transportan	Peptides	Cancer
Transportan is a 27 amino acid-long peptide containing 12 functional amino acids from the amino terminus of the neuropeptide galanin and mastoparan in the carboxyl terminus, connected via a lysine. Transportan belongs to cell-penetrating peptides (CPPs) .

HY-P1781

Peptide C105Y	Peptides	Cancer
Peptide C105Y, a synthetic and cell-penetrating peptide based on the amino acid sequence corresponding to residues 359-374 of α1-antitrypsin, enhances gene expression from DNA nanoparticles .

HY-P4119

Pep-1-Cysteamine	Peptides	Others
Pep-1-Cysteamine is a chimeric cell-penetrating peptide (CPP) with a primary amphipathicity. Pep-1-Cysteamine has the ability to translocate across biological membranes and introduce active proteins inside cells .

HY-P1491

HIV-1 TAT (48-60)	HIV	Infection
HIV-1 TAT (48-60) is a cell-penetrating peptide derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. It has been used to deliver exogenous macromolecules into cells in a non-disruptive way.

HY-P2483A

Octaarginine TFA	Peptides	Others
Octaarginine TFA is a cell-penetrating peptide (CPP). CPPs show membrane translocation activities. CPPs are used for intracellular delivery of various membrane-impermeable bioactive agents because of their intrinsic ability to gain access to cell interiors. CPPs have also been used to deliver antibacterial agents to target intracellular bacteria .

HY-P4250

Arg-Arg-Arg-Arg

Peptides Others

Tetraarginine (RRRR), consisting of four arginines, is used in cell-penetrating peptide-based gene delivery vehicles .
HY-P5284

RALA peptide

Peptides Others

RALA peptide is a cell-penetrating peptide. RALA peptide can be as non-viral gene delivery vectors .

HY-P10153

gH625	Peptides	Others
gH625 is a cell-penetrating viral peptide which is a part of glycoprotein H of Herpes simplex virus type I. gH625 is able to cross the cell membrane and to transport many conjugated cargoes into the cytosol. gH625 is permeable to the blood-brain barrier (BBB) and can enter the rat brain in vivo without toxic effects. gH625 can be used for siRNA delivery research .

HY-P4250A

Arg-Arg-Arg-Arg acetate

Peptides Others

Arg-Arg-Arg-Arg (acetate), consisting of four arginines, is used in cell-penetrating peptide-based gene delivery vehicles .

HY-P4108

TAT-HA2 Fusion Peptide	Influenza Virus	Others
TAT-HA2 Fusion Peptide is a peptide-based delivery agent that combines the pH-sensitive HA2 fusion peptide from Influenza and the cell-penetrating peptide TAT from HIV. TAT-HA2 Fusion Peptide induces the cellular uptake of macromolecules into endosomes via the TAT moiety and to respond to the acidifying lumen of endosomes to cause membrane leakage and release of macromolecules into cells via the HA2 moiety .

HY-107146

PZ-128 P1pal-7	Protease Activated Receptor (PAR)	Cardiovascular Disease Cancer
PZ-128 (P1pal-7), a cell-penetrating lipopeptide pepducin, is a first-in-class, specific and reversible protease-activated receptor-1 (PAR1) antagonist. PZ-128 targets the cytoplasmic surface of PAR1 and interrupts signaling to internally-located G (PAR1-G) proteins. PZ-128 has antiplatelet, anti-metastatic, anti-angiogenic and anticancer effects .

HY-P5107

Protein LMWP	VEGFR	Cancer
Protein LMWP is a cell-penetrating peptide with vascular endothelial growth factor (VEGF) inhibitory activity. Protein LMWP can inhibit tumor growth and is used in cancer research .

HY-P2262

TAT-DEF-Elk-1 1 Publications Verification TDE	Peptides	Neurological Disease
TAT-DEF-Elk-1 (TDE) is a cell-penetrating peptide inhibitor of Elk-1, mimics and specifically interferes with the DEF domain of Elk-1. TAT-DEF-Elk-1 blocks Elk-1 phosphorylation and prevents Elk-1 nuclear translocation without interfering with ERK nor MSK1 activation. TAT-DEF-Elk-1 is a useful tool to analyze the role of Elk-1 in this process during the development of neuronal plasticity .

HY-P2262A

TAT-DEF-Elk-1 TFA TDE TFA	Peptides	Neurological Disease
TAT-DEF-Elk-1 TFA (TDE TFA) is a cell-penetrating peptide inhibitor of Elk-1, mimics and specifically interferes with the DEF domain of Elk-1. TAT-DEF-Elk-1 TFA blocks Elk-1 phosphorylation and prevents Elk-1 nuclear translocation without interfering with ERK nor MSK1 activation. TAT-DEF-Elk-1 TFA is a useful tool to analyze the role of Elk-1 in this process during the development of neuronal plasticity .

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