NGR peptide
Based on 1 publication(s) in Google Scholar
NGR peptide containing the Asn-Gly-Arg (NGR) motif. NGR peptide binds to APN/CD13. NGR peptide is directly conjugated to imaging agents that can be used for tumor imaging.
For research use only. We do not sell to patients.
- Purity: 99.73%
- CAS No.: 651328-78-8
- Formula: C20H36N10O8S2
- Molecular Weight:608.69
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications Citing Use of MedChemExpress (MCE) NGR peptide
More
Biological Activity
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CD13 |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:4-6 weeks, BALB/c nude mice (HepG2 tumor model)[2]
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Dosage:20 mg/kg
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Administration:I.v.
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Result:Blocked the tumor uptake for 99mTc-NGR.
Chemical Information
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CAS No. 651328-78-8
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Appearance Solid
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Molecular Weight 608.69
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Formula C20H36N10O8S2
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Color White to off-white
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Sequence
Cys-Asn-Gly-Arg-Cys-Gly
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Sequence Shortening
CNGRCG
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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Adv Mater
Dismantlable Coronated Nanoparticles for Coupling the Induction and Perception of Immunogenic Cell Death. [Abstract]2024 Apr 21:e2313097. PMID: 38643386
Solvent & Solubility
DMSO : 100 mg/mL (164.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Wang RE, et al. Development of NGR peptide-based agents for tumor imaging. Am J Nucl Med Mol Imaging. 2011;1(1):36-46. [Content Brief]
[2]. Ma W, et al. Biodistribution and SPECT imaging study of (99m)Tc labeling NGR peptide in nude mice bearing human HepG2 hepatoma. Biomed Res Int. 2014;2014:618096. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6429 mL | 8.2144 mL | 16.4287 mL | 41.0718 mL |
| 5 mM | 0.3286 mL | 1.6429 mL | 3.2857 mL | 8.2144 mL | |
| 10 mM | 0.1643 mL | 0.8214 mL | 1.6429 mL | 4.1072 mL | |
| 15 mM | 0.1095 mL | 0.5476 mL | 1.0952 mL | 2.7381 mL | |
| 20 mM | 0.0821 mL | 0.4107 mL | 0.8214 mL | 2.0536 mL | |
| 25 mM | 0.0657 mL | 0.3286 mL | 0.6571 mL | 1.6429 mL | |
| 30 mM | 0.0548 mL | 0.2738 mL | 0.5476 mL | 1.3691 mL | |
| 40 mM | 0.0411 mL | 0.2054 mL | 0.4107 mL | 1.0268 mL | |
| 50 mM | 0.0329 mL | 0.1643 mL | 0.3286 mL | 0.8214 mL | |
| 60 mM | 0.0274 mL | 0.1369 mL | 0.2738 mL | 0.6845 mL | |
| 80 mM | 0.0205 mL | 0.1027 mL | 0.2054 mL | 0.5134 mL | |
| 100 mM | 0.0164 mL | 0.0821 mL | 0.1643 mL | 0.4107 mL |