2. Metabolic Enzyme/Protease
  3. Aminopeptidase
  4. NGR peptide

NGR peptide containing the Asn-Gly-Arg (NGR) motif. NGR peptide binds to APN/CD13. NGR peptide is directly conjugated to imaging agents that can be used for tumor imaging.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

NGR peptide

NGR peptide Chemical Structure

CAS No. : 651328-78-8

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Based on 1 publication(s) in Google Scholar

Other Forms of NGR peptide:

NGR peptide Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE NGR peptide

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CD13 LTA4H

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

NGR peptide containing the Asn-Gly-Arg (NGR) motif. NGR peptide binds to APN/CD13. NGR peptide is directly conjugated to imaging agents that can be used for tumor imaging[1][2].

IC50 & Target[1][2]

CD13

 

In Vivo

NGR peptide (20 mg/kg; i.v.) can be used as a potential SPECT agent for imaging and early diagnosis of tumor[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 4-6 weeks, BALB/c nude mice (HepG2 tumor model)[2]
Dosage: 20 mg/kg
Administration: I.v.
Result: Blocked the tumor uptake for 99mTc-NGR.
Molecular Weight

608.69

Formula

C20H36N10O8S2
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Cys-Asn-Gly-Arg-Cys-Gly
Sequence Shortening

CNGRCG
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (164.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6429 mL 8.2144 mL 16.4287 mL
5 mM 0.3286 mL 1.6429 mL 3.2857 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6429 mL 8.2144 mL 16.4287 mL 41.0718 mL
5 mM 0.3286 mL 1.6429 mL 3.2857 mL 8.2144 mL
10 mM 0.1643 mL 0.8214 mL 1.6429 mL 4.1072 mL
15 mM 0.1095 mL 0.5476 mL 1.0952 mL 2.7381 mL
20 mM 0.0821 mL 0.4107 mL 0.8214 mL 2.0536 mL
25 mM 0.0657 mL 0.3286 mL 0.6571 mL 1.6429 mL
30 mM 0.0548 mL 0.2738 mL 0.5476 mL 1.3691 mL
40 mM 0.0411 mL 0.2054 mL 0.4107 mL 1.0268 mL
50 mM 0.0329 mL 0.1643 mL 0.3286 mL 0.8214 mL
60 mM 0.0274 mL 0.1369 mL 0.2738 mL 0.6845 mL
80 mM 0.0205 mL 0.1027 mL 0.2054 mL 0.5134 mL
100 mM 0.0164 mL 0.0821 mL 0.1643 mL 0.4107 mL
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NGR peptide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NGR peptide651328-78-8AminopeptidaseInhibitorinhibitorinhibit

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