1. Metabolic Enzyme/Protease
  2. Aminopeptidase
  3. NGR peptide Trifluoroacetate

NGR peptide Trifluoroacetate 

Cat. No.: HY-P1043A Purity: 98.55%
Handling Instructions

NGR peptide Trifluoroacetate containing the asparagine-glycine-arginine (NGR) motif is recognized by CD13/aminopeptidase N (APN) receptor isoforms that are selectively overexpressed in tumor neovasculature.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

NGR peptide Trifluoroacetate Chemical Structure

NGR peptide Trifluoroacetate Chemical Structure

Size Price Stock Quantity
10 mM * 1 mL in Water USD 572 In-stock
Estimated Time of Arrival: December 31
1 mg USD 120 In-stock
Estimated Time of Arrival: December 31
5 mg USD 360 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

NGR peptide Trifluoroacetate containing the asparagine-glycine-arginine (NGR) motif is recognized by CD13/aminopeptidase N (APN) receptor isoforms that are selectively overexpressed in tumor neovasculature.

IC50 & Target

CD13/aminopeptidase N (APN) receptor[1]

In Vitro

NGR peptide can selectively bind to APN/CD13 either immune-captured or expressed on the surface of cells, the receptor of the tumor-homing NGR peptide was suspected to be APN/CD13. The NGR peptide is reported to have the greatest tumor selectivity. An anti-cancer drug Doxorubicin (DOX) coupled to an NGR peptide displays enhanced anti-tumor effects with even lower toxicity than the free drug itself[2].

In Vivo

NGR peptide imaging in vivo not only provides more insight into NGR’s targeting process, including bio-distribution and pharmacokinetics, but also reveals angiogenic activities related to tumor progression and malignancy[2].

Molecular Weight

722.72

Formula

C₂₂H₃₇F₃N₁₀O₁₀S₂

Sequence

Cys-Asn-Gly-Arg-Cys-Gly

Sequence Shortening

CNGRCG

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (138.37 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3837 mL 6.9183 mL 13.8366 mL
5 mM 0.2767 mL 1.3837 mL 2.7673 mL
10 mM 0.1384 mL 0.6918 mL 1.3837 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

NGR peptideAminopeptidaseInhibitorinhibitorinhibit

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Product name:
NGR peptide Trifluoroacetate
Cat. No.:
HY-P1043A
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