1. Metabolic Enzyme/Protease
  2. Aminopeptidase
  3. NGR peptide Trifluoroacetate

NGR peptide Trifluoroacetatecontaining the Asn-Gly-Arg (NGR) motif. NGR peptide Trifluoroacetate binds to APN/CD13. NGR peptide Trifluoroacetate is directly conjugated to imaging agents that can be used for tumor imaging.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

NGR peptide Trifluoroacetate Chemical Structure

NGR peptide Trifluoroacetate Chemical Structure

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in Water
ready for reconstitution
USD 143 In-stock
Solution
10 mM * 1 mL in Water USD 143 In-stock
Solid
5 mg USD 90 In-stock
10 mg USD 140 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of NGR peptide Trifluoroacetate:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

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  • Customer Review

Description

NGR peptide Trifluoroacetatecontaining the Asn-Gly-Arg (NGR) motif. NGR peptide Trifluoroacetate binds to APN/CD13. NGR peptide Trifluoroacetate is directly conjugated to imaging agents that can be used for tumor imaging[1][2].

IC50 & Target[1][2]

CD13

 

In Vivo

NGR peptide Trifluoroacetate (20 mg/kg; i.v.) can be used as a potential SPECT agent for imaging and early diagnosis of tumor[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 4-6 weeks, BALB/c nude mice (HepG2 tumor model)[2]
Dosage: 20 mg/kg
Administration: I.v.
Result: Blocked the tumor uptake for 99mTc-NGR.
Molecular Weight

722.72

Formula

C22H37F3N10O10S2

Appearance

Solid

Color

White to off-white

Sequence

Cys-Asn-Gly-Arg-Cys-Gly

Sequence Shortening

CNGRCG

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (69.18 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3837 mL 6.9183 mL 13.8366 mL
5 mM 0.2767 mL 1.3837 mL 2.7673 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (138.37 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.3837 mL 6.9183 mL 13.8366 mL 34.5915 mL
5 mM 0.2767 mL 1.3837 mL 2.7673 mL 6.9183 mL
10 mM 0.1384 mL 0.6918 mL 1.3837 mL 3.4592 mL
15 mM 0.0922 mL 0.4612 mL 0.9224 mL 2.3061 mL
20 mM 0.0692 mL 0.3459 mL 0.6918 mL 1.7296 mL
25 mM 0.0553 mL 0.2767 mL 0.5535 mL 1.3837 mL
30 mM 0.0461 mL 0.2306 mL 0.4612 mL 1.1531 mL
40 mM 0.0346 mL 0.1730 mL 0.3459 mL 0.8648 mL
50 mM 0.0277 mL 0.1384 mL 0.2767 mL 0.6918 mL
60 mM 0.0231 mL 0.1153 mL 0.2306 mL 0.5765 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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NGR peptide Trifluoroacetate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
NGR peptide Trifluoroacetate
Cat. No.:
HY-P1043A
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