2. Protein Tyrosine Kinase/RTK
    Immunology/Inflammation
  3. Src
    Interleukin Related
  4. Lyn peptide inhibitor TFA

Lyn peptide inhibitor TFA 

Cat. No.: HY-P1111A
Handling Instructions

Lyn peptide inhibitor TFA is a potent and cell-permeable inhibitor of Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact. Lyn peptide inhibitor TFA blocks Lyn activation and inhibits the binding of Lyn tyrosine kinase to βc subunit of IL-3/GM-CSF/IL-5 receptors. Lyn peptide inhibitor TFA can be used for study of  asthma, allergic, and other eosinophilic disorders.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Lyn peptide inhibitor TFA Chemical Structure

Lyn peptide inhibitor TFA Chemical Structure

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Description

Lyn peptide inhibitor TFA is a potent and cell-permeable inhibitor of Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact. Lyn peptide inhibitor TFA blocks Lyn activation and inhibits the binding of Lyn tyrosine kinase to βc subunit of IL-3/GM-CSF/IL-5 receptors. Lyn peptide inhibitor TFA can be used for study of  asthma, allergic, and other eosinophilic disorders[1].

IC50 & Target[1][2]

IL-5

 

IL-3

 

Molecular Weight

2484.90

Formula

C116H186F3N30O26
Sequence

Stearoyl-Tyr-Gly-Tyr-Arg-Leu-Arg-Arg-Lys-Trp-Glu-Glu-Lys-Ile-Pro-Asn-Pro-NH2
Sequence Shortening

Stearoyl-YGYRLRRKWEEKIPNP-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

Lyn peptide inhibitorSrcInterleukin RelatedILasthmaallergiceosinophilicdisorderinflammation,Lyn-coupledLyn kinaseInhibitorinhibitorinhibit

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