1. Protein Tyrosine Kinase/RTK Immunology/Inflammation
  2. Src Interleukin Related
  3. Lyn peptide inhibitor

Lyn peptide inhibitor is a potent and cell-permeable inhibitor of Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact. Lyn peptide inhibitor blocks Lyn activation and inhibits the binding of Lyn tyrosine kinase to βc subunit of IL-3/GM-CSF/IL-5 receptors. Lyn peptide inhibitor can be used for study of  asthma, allergic, and other eosinophilic disorders.

For research use only. We do not sell to patients.

Lyn peptide inhibitor Chemical Structure

Lyn peptide inhibitor Chemical Structure

CAS No. : 222018-18-0

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Description

Lyn peptide inhibitor is a potent and cell-permeable inhibitor of Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact. Lyn peptide inhibitor blocks Lyn activation and inhibits the binding of Lyn tyrosine kinase to βc subunit of IL-3/GM-CSF/IL-5 receptors. Lyn peptide inhibitor can be used for study of  asthma, allergic, and other eosinophilic disorders[1].

IC50 & Target[1][2]

IL-5

 

IL-3

 

Molecular Weight

2370.88

Formula

C115H184N30O24

CAS No.
Sequence

Stearoyl-Tyr-Gly-Tyr-Arg-Leu-Arg-Arg-Lys-Trp-Glu-Glu-Lys-Ile-Pro-Asn-Pro-NH2

Sequence Shortening

Stearoyl-YGYRLRRKWEEKIPNP-NH2

SMILES

[Stearoyl-YGYRLRRKWEEKIPNP-NH2]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Lyn peptide inhibitor Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Lyn peptide inhibitor
Cat. No.:
HY-P1111
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