1. Protein Tyrosine Kinase/RTK
    Immunology/Inflammation
  2. Src
    Interleukin Related
  3. Lyn peptide inhibitor

Lyn peptide inhibitor 

Cat. No.: HY-P1111
Handling Instructions

Lyn peptide inhibitor is a potent and cell-permeable inhibitor of Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact. Lyn peptide inhibitor blocks Lyn activation and inhibits the binding of Lyn tyrosine kinase to βc subunit of IL-3/GM-CSF/IL-5 receptors. Lyn peptide inhibitor can be used for study of  asthma, allergic, and other eosinophilic disorders.

For research use only. We do not sell to patients.

Lyn peptide inhibitor Chemical Structure

Lyn peptide inhibitor Chemical Structure

CAS No. : 222018-18-0

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Description

Lyn peptide inhibitor is a potent and cell-permeable inhibitor of Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact. Lyn peptide inhibitor blocks Lyn activation and inhibits the binding of Lyn tyrosine kinase to βc subunit of IL-3/GM-CSF/IL-5 receptors. Lyn peptide inhibitor can be used for study of  asthma, allergic, and other eosinophilic disorders[1].

IC50 & Target

IC50: Lyn kinase[1]

Molecular Weight

2370.88

Formula

C₁₁₅H₁₈₄N₃₀O₂₄

CAS No.

222018-18-0

Sequence

Stearoyl-Tyr-Gly-Tyr-Arg-Leu-Arg-Arg-Lys-Trp-Glu-Glu-Lys-Ile-Pro-Asn-Pro-NH2

Sequence Shortening

Stearoyl-YGYRLRRKWEEKIPNP-NH2

SMILES

[Stearoyl-YGYRLRRKWEEKIPNP-NH2]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Lyn peptide inhibitorSrcInterleukin RelatedILasthmaallergiceosinophilicdisorderinflammationLyn-coupledLyn kinaseInhibitorinhibitorinhibit

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Lyn peptide inhibitor
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HY-P1111
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