HAIYPRH hydrochloride
Based on 1 Customer Validation
HAIYPRH hydrochloride, a targeting ligand, can specially bind to transferrin receptor (TfR). HAIYPRH hydrochloride can mediate the transport of nanocarriers across the blood-brain barrier.
For research use only. We do not sell to patients.
- Purity: 99.97%
- Formula: C41H61ClN14O9
- Molecular Weight:929.46
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Storage:
Sealed storage, away from moisture and light, under nitrogen.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Biological Activity
HAIYPRH hydrochloride (T7) is conjugated to liposomes for ischemic stroke targeting treatment of a novel neuroprotectant (HY-100456: ZL006)[2].
HAIYPRH hydrochloride is a heptapeptide that can be used to target gliomas[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 929.46
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Formula C41H61ClN14O9
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Color White to off-white
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Sequence Shortening
HAIYPRH
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light, under nitrogen
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Solvent & Solubility
H2O : ≥ 100 mg/mL (107.59 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Liu S, et al. Gene and doxorubicin co-delivery system for targeting therapy of glioma. Biomaterials. 2012;33(19):4907‐4916. [Content Brief]
[2]. Wang Z, et al. Enhanced anti-ischemic stroke of ZL006 by T7-conjugated PEGylated liposomes drug delivery system. Sci Rep. 2015;5:12651. Published 2015 Jul 29. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.0759 mL | 5.3795 mL | 10.7589 mL | 26.8973 mL |
| 5 mM | 0.2152 mL | 1.0759 mL | 2.1518 mL | 5.3795 mL | |
| 10 mM | 0.1076 mL | 0.5379 mL | 1.0759 mL | 2.6897 mL | |
| 15 mM | 0.0717 mL | 0.3586 mL | 0.7173 mL | 1.7932 mL | |
| 20 mM | 0.0538 mL | 0.2690 mL | 0.5379 mL | 1.3449 mL | |
| 25 mM | 0.0430 mL | 0.2152 mL | 0.4304 mL | 1.0759 mL | |
| 30 mM | 0.0359 mL | 0.1793 mL | 0.3586 mL | 0.8966 mL | |
| 40 mM | 0.0269 mL | 0.1345 mL | 0.2690 mL | 0.6724 mL | |
| 50 mM | 0.0215 mL | 0.1076 mL | 0.2152 mL | 0.5379 mL | |
| 60 mM | 0.0179 mL | 0.0897 mL | 0.1793 mL | 0.4483 mL | |
| 80 mM | 0.0134 mL | 0.0672 mL | 0.1345 mL | 0.3362 mL | |
| 100 mM | 0.0108 mL | 0.0538 mL | 0.1076 mL | 0.2690 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.