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  2. HAIYPRH hydrochloride

HAIYPRH hydrochloride 

Cat. No.: HY-P2314
Handling Instructions

HAIYPRH hydrochloride, a targeting ligand, can specially bind to transferrin receptor (TfR). HAIYPRH hydrochloride can mediate the transport of nanocarriers across the blood-brain barrier.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

HAIYPRH hydrochloride Chemical Structure

HAIYPRH hydrochloride Chemical Structure

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Description

HAIYPRH hydrochloride, a targeting ligand, can specially bind to transferrin receptor (TfR). HAIYPRH hydrochloride can mediate the transport of nanocarriers across the blood-brain barrier[1].

In Vitro

HAIYPRH hydrochloride (T7) is conjugated to liposomes for ischemic stroke targeting treatment of a novel neuroprotectant (HY-100456: ZL006)[2].
HAIYPRH hydrochloride is a heptapeptide that can be used to target gliomas[3].

In Vivo

HAIYPRH hydrochloride, a transferrin receptor-specific peptide, is chosen as the ligand to target the co-delivery system to the tumor cells expressing transferrin receptors. HAIYPRH-modified co-delivery system shows higher efficiency in cellular uptake and gene expression than unmodified co-delivery system in U87 MG cells, and accumulated in tumor more efficiently in vivo[1].

Molecular Weight

929.46

Formula

C₄₁H₆₁ClN₁₄O₉

Sequence

{His}{Ala}{Ile}{Tyr}{Pro}{Arg}{His}

Sequence Shortening

HAIYPRH

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

HAIYPRHOthersliposomesneuroprotectantheptapeptidegliomastumorInhibitorinhibitorinhibit

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Product name:
HAIYPRH hydrochloride
Cat. No.:
HY-P2314
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