2. Peptides
  3. HAIYPRH hydrochloride

HAIYPRH hydrochloride, a targeting ligand, can specially bind to transferrin receptor (TfR). HAIYPRH hydrochloride can mediate the transport of nanocarriers across the blood-brain barrier.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

HAIYPRH hydrochloride Chemical Structure

HAIYPRH hydrochloride Chemical Structure

Size Price Stock Quantity
5 mg USD 70 In-stock
10 mg USD 120 In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

HAIYPRH hydrochloride Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

HAIYPRH hydrochloride, a targeting ligand, can specially bind to transferrin receptor (TfR). HAIYPRH hydrochloride can mediate the transport of nanocarriers across the blood-brain barrier[1].

In Vitro

HAIYPRH hydrochloride (T7) is conjugated to liposomes for ischemic stroke targeting treatment of a novel neuroprotectant (HY-100456: ZL006)[2].
HAIYPRH hydrochloride is a heptapeptide that can be used to target gliomas[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

HAIYPRH hydrochloride Related Antibodies
In Vivo

HAIYPRH hydrochloride, a transferrin receptor-specific peptide, is chosen as the ligand to target the co-delivery system to the tumor cells expressing transferrin receptors. HAIYPRH-modified co-delivery system shows higher efficiency in cellular uptake and gene expression than unmodified co-delivery system in U87 MG cells, and accumulated in tumor more efficiently in vivo[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

929.46

Formula

C41H61ClN14O9
Appearance

Solid

Color

White to off-white

Sequence Shortening

HAIYPRH
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (107.59 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0759 mL 5.3795 mL 10.7589 mL
5 mM 0.2152 mL 1.0759 mL 2.1518 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.0759 mL 5.3795 mL 10.7589 mL 26.8973 mL
5 mM 0.2152 mL 1.0759 mL 2.1518 mL 5.3795 mL
10 mM 0.1076 mL 0.5379 mL 1.0759 mL 2.6897 mL
15 mM 0.0717 mL 0.3586 mL 0.7173 mL 1.7932 mL
20 mM 0.0538 mL 0.2690 mL 0.5379 mL 1.3449 mL
25 mM 0.0430 mL 0.2152 mL 0.4304 mL 1.0759 mL
30 mM 0.0359 mL 0.1793 mL 0.3586 mL 0.8966 mL
40 mM 0.0269 mL 0.1345 mL 0.2690 mL 0.6724 mL
50 mM 0.0215 mL 0.1076 mL 0.2152 mL 0.5379 mL
60 mM 0.0179 mL 0.0897 mL 0.1793 mL 0.4483 mL
80 mM 0.0134 mL 0.0672 mL 0.1345 mL 0.3362 mL
100 mM 0.0108 mL 0.0538 mL 0.1076 mL 0.2690 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HAIYPRHliposomesneuroprotectantheptapeptidegliomastumorInhibitorinhibitorinhibit

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HAIYPRH hydrochloride
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