JNK-IN-12
JNK-IN-12 (compound P2) is a mitochondrial-targeted JNK inhibitor (IC50=66.3 nM), consisting of a mitochondrial-specific cell-penetrating peptide and a specific inhibitor of JNK, SP600125 (HY-12041). JNK-IN-12 doesn't inhibit nuclear JNK signaling, but does inhibit mitochondrial JNK phosphorylation. JNK-IN-12 helps to improve the Parkinson's disease (PD) both in vitro and in vivo.
For research use only. We do not sell to patients.
- Formula: C56H82N16O7
- Molecular Weight:1091.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 66.3 nM (JNK)[1]
Chemical Information
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Molecular Weight 1091.35
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Formula C56H82N16O7
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SMILES
O=C1C2=C(NCCNC(CCCC3=CN(CCCC(N[C@H](C(N[C@H](CCCNC(N)=N)C(N[C@H](C(N[C@H](C(N)=O)CCCCN)=O)CC4CCCCC4)=O)=O)CC5CCCCC5)=O)N=N3)=O)C=CC=C2C6=NNC7=C6C1=CC=C7
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JNK-IN-12 Related Classifications
HY-155077 Related Classifications
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