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  2. TfR-T12

TfR-T12 

Cat. No.: HY-P2297
Handling Instructions

TfR-T12 is a BBB-penetrated transferrin receptor (TfR) binding peptide, displaying a binding affinity in the nM range.

For research use only. We do not sell to patients.

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TfR-T12 Chemical Structure

TfR-T12 Chemical Structure

CAS No. : 344618-30-0

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Description

TfR-T12 is a BBB-penetrated transferrin receptor (TfR) binding peptide, displaying a binding affinity in the nM range[1][2].

In Vitro

TfR-T12 binds to the TfR and is subsequently internalized into TfR-expressing cells[1].
TfR-T12 is a synthetic peptide obtained by phage display, and is able to bind a different site on TfRs compared with transferrin. TfR-T12 can be chemically conjugated with a pegylated lipid derivative, 3-(N-succinimidyloxyglutaryl)aminopropyl- polyethyleneglycol(2000)- carbamyl distearoyl phosphatidylethanolamine (NHS-PEG2000-DSPE), and used as a functional material to construct the multifunctional lipid vesicles[2].

Molecular Weight

1490.73

Formula

C₇₁H₉₉N₁₉O₁₅S

CAS No.

344618-30-0

Sequence

{Thr}{His}{Arg}{Pro}{Pro}{Met}{Trp}{Ser}{Pro}{Val}{Trp}{Pro}

Sequence Shortening

THRPPMWSPVWP

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

TfR-T12OthersInhibitorinhibitorinhibit

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