344618-30-0
344618-30-0
Chemical Structure
TfR-T12
- CAS No.: 344618-30-0
- Formula:C71H99N19O15S
- Molecular Weight:1490.73
InChIKey: DZRUHTLPVFYMDV-YMGLLDFPSA-N
SMILES: O=C(N(CCC1)[C@@H]1C(O)=O)[C@@H](NC([C@H](C(C)C)NC([C@H](CCC2)N2C([C@H](CO)NC([C@@H](NC([C@H](CCSC)NC([C@H](CCC3)N3C([C@H](CCC4)N4C([C@H](CCCNC(N)=N)NC([C@@H](NC([C@@H](N)[C@H](O)C)=O)CC5=CN=CN5)=O)=O)=O)=O)=O)CC6=CNC7=CC=CC=C67)=O)=O)=O)=O)CC8=CNC9=CC=CC=C89
Biological Activity: TfR-T12 is a BBB-penetrated transferrin receptor (TfR) binding peptide, displaying a binding affinity in the nM range[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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TfR-T12 | 99.72% | TfR-T12 is a BBB-penetrated transferrin receptor (TfR) binding peptide, displaying a binding affinity in the nM range. | ||||||||||||||||||||
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References
- [1]. Carmen Wängler, et al. In Vitro and Initial in Vivo Evaluation of (68)Ga-labeled Transferrin Receptor (TfR) Binding Peptides as Potential Carriers for Enhanced Drug Transport Into TfR Expressing Cells. Mol Imaging Biol. 2011 Apr;13(2):332-41. [Content Brief]
- [2]. Li-Min Mu, et al. Lipid Vesicles Containing Transferrin Receptor Binding Peptide TfR-T 12 and Octa-Arginine Conjugate stearyl-R 8 Efficiently Treat Brain Glioma Along With Glioma Stem Cells. Sci Rep. 2017 Jun 14;7(1):3487. [Content Brief]
