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(Arg)9 acetate (Synonyms: Nona-L-arginine acetate; Peptide R9 acetate)

Cat. No.: HY-P0133B Purity: 99.12%
Handling Instructions

(Arg)9 (Nona-L-arginine) acetate is a cell-penetrating peptide (CPP) made up of 9 arginine residues. (Arg)9 acetate has neuroprotective property, exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

(Arg)9 acetate Chemical Structure

(Arg)9 acetate Chemical Structure

Size Price Stock Quantity
1 mg USD 170 In-stock
Estimated Time of Arrival: December 31
5 mg USD 510 In-stock
Estimated Time of Arrival: December 31
10 mg USD 790 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of (Arg)9 acetate:

Top Publications Citing Use of Products

1 Publications Citing Use of MCE (Arg)9 acetate

  • Biological Activity

  • Purity & Documentation

  • Customer Review

Description

(Arg)9 (Nona-L-arginine) acetate is a cell-penetrating peptide (CPP) made up of 9 arginine residues. (Arg)9 acetate has neuroprotective property, exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model[1][2].

IC50 & Target

IC50: 0.78 μM (neuroprotection)[1]

In Vitro

(Arg)9 (Nona-L-arginine; 5-10 μM) acetate provides significant neuroprotection in a dose–response manner following glutamic acid exposure (IC50=0.78 μM). Following kainic acid exposure, (Arg)9 acetate is neuroprotective, but less effective than in the glutamic acid model (IC50=0.81 μM). (Arg)9 acetate also shows neuroprotection following in vitro ischemia (IC50=6 μM)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

(Arg)9 (Nona-L-arginine; 1 μM/kg (600  μL); i.v.; once, for 30min; male Sprague–Dawley ratspermanent middle cerebral artery stroke model) acetate shows neuroprotective effects and reduces infarct volume[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague–Dawley rats (270 to 320 g) permanent middle cerebral artery stroke model[2]
Dosage: 1 μM/kg (600  μL)
Administration: Intravenous injection; once, over 5 minutes
Result: Reduced significantiy 20% in infarct volume.
Molecular Weight

1483.74

Formula

C56H114N36O12

Sequence Shortening

RRRRRRRRR

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Protect from light, stored under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (67.40 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6740 mL 3.3699 mL 6.7397 mL
5 mM 0.1348 mL 0.6740 mL 1.3479 mL
10 mM 0.0674 mL 0.3370 mL 0.6740 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
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Product Name:
(Arg)9 acetate
Cat. No.:
HY-P0133B
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