Copy Link Print Information

740 Y-P TFA

(Synonyms: 740YPDGFR TFA; PDGFR 740Y-P TFA)
261 Cited Publications
고객리뷰

Based on 261 publication(s) in Google Scholar

740 Y-P TFA is a potent and cell-permeable PI3K activator. 740 Y-P TFA readily binds GST fusion proteins containing both the N- and C- terminal SH2 domains of p85 but fails to bind GST alone.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

  • 화학식: C141H222N43O39PS3.xC2HF3O2
  • 분자량:3270.70 (free acid)
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • 740 Y-P TFA Chemical Structure
    740 Y-P TFA Chemical Structure
  • Experimental Validation Results for 740 Y-P TFA
  • Experimental Validation Results for 740 Y-P TFA
  • Experimental Validation Results for 740 Y-P TFA
  • Experimental Validation Results for 740 Y-P TFA
  • Experimental Validation Results for 740 Y-P TFA
사이즈
가격
재고
수량
Amount: USD 0.00
Please select quantity
or
or

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Other Forms of 740 Y-P TFA:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
주변의 대리점 찾기 Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • 순도&문서
  • References
  • Help & FAQs
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) 740 Y-P TFA

More
Customer Validation & Images
WB
  • WB
  • WB
  • WB
  • WB
  • WB

All PI3K Isoforms

More
Keywords
MOQ
Minimum order quantity
100 mg

견적 받기 해외재고보유

Other size
견적 받기
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress 로그인
Register
Sign in to MedChemExpress
회원가입

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 740 Y-P TFA Chemical Structure
    740 Y-P TFA Chemical Structure
    1/16
  • 1/16

    740 Y-P TFA purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Apr;12(13):e2410032. [Abstract]

    Customer Validation
     Protein expression and quantification of SGLT1, GLUT2, p-PI3K, p-AKT, p-S6K1, and p-eIF4B were performed. GAPDH was used to normalize the data. 740Y-P (30 μM; 24 h) was an activator of the PI3K/Akt signaling pathway.

  • 1/16

    740 Y-P TFA purchased from MedChemExpress. Usage Cited in: Theranostics. 2024 Jul 8;14(11):4278-4296. [Abstract]

    Customer Validation
     Western blotting was used to measure p-PI3K/PI3K, p-AKT/AKT, and p-mTOR/mTOR expression in MODE-K cells incubated with 740 Y-P (25 μg/mL; 24 h).

  • 1/16

    740 Y-P TFA purchased from MedChemExpress. Usage Cited in: Exp Mol Med. 2023 May;55(5):939-951. [Abstract]

    Customer Validation
     Western blot showing PI3K, AKT, p-AKT, GPX4, ACSL4, TFR1, and SLC7A11 in the tissue samples of ApoE−/− mice infused with saline or Ang II, with or without 740 Y-P (10 mg/kg/d) treatment. n = 3 in each group.

  • 1/16

    740 Y-P TFA purchased from MedChemExpress. Usage Cited in: J Exp Clin Cancer Res. 2020 Jun 30;39(1):123. [Abstract]

    Customer Validation
     Protein expression levels of p-AktSer473, p-mTORSer2448 with or without 740Y-P treatment are measured by Western blotting. Pretreatment with 740Y-P (PI3K agonist) inhibits downregulation of p-AktSer473 and p-mTORSer2448 expression induced by overexpression of BDH2.

  • 1/16

    740 Y-P TFA purchased from MedChemExpress. Usage Cited in: Acta Biomater. 2018 Nov:81:278-292. [Abstract]

    Customer Validation
     PC12 cells are pretreated with 740-YP (30 μM), or SC79 (13.7 μM), or 3BDO (100 μM) for 1 h, and for the duration of GO (50 μg/mL) incubation for 24 h. LC3 turnover is detected by western blotting.

  • 740 Y-P TFA