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11R-VIVIT 

Cat. No.: HY-P1430
Handling Instructions

11R-VIVIT is a potent NFAT inhibitor. 11R-VIVIT inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). 11R-VIVIT also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. 11R-VIVIT improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice.

For research use only. We do not sell to patients.

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11R-VIVIT Chemical Structure

11R-VIVIT Chemical Structure

CAS No. : 592517-80-1

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Description

11R-VIVIT is a potent NFAT inhibitor. 11R-VIVIT inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). 11R-VIVIT also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. 11R-VIVIT improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice.

Molecular Weight

3573.15

Formula

C₁₄₇H₂₅₉N₆₇O₃₆S

CAS No.

592517-80-1

Sequence

Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Gly-Gly-Gly-Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu

Sequence Shortening

RRRRRRRRRRRGGGMAGPHPVIVITGPHEE

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Keywords:

11R-VIVITOthersInhibitorinhibitorinhibit

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11R-VIVIT
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