1. Metabolic Enzyme/Protease
    Apoptosis
  2. MMP
    Apoptosis
  3. GPLGIAGQ TFA

GPLGIAGQ TFA 

Cat. No.: HY-P2213A
Handling Instructions

GPLGIAGQ TFA, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ TFA can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT).

For research use only. We do not sell to patients.

Custom Peptide Synthesis

GPLGIAGQ TFA Chemical Structure

GPLGIAGQ TFA Chemical Structure

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Description

GPLGIAGQ TFA, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ TFA can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT)[1][2][3].

IC50 & Target

MMP2[1].

In Vitro

GPLGIAGQ is used to trigger PEG deshielding of liposomal carriers, resulting in enhanced cellular internalization[3].

Molecular Weight

825.83

Formula

C₃₃H₅₄F₃N₉O₁₂

Sequence

{Gly}{Pro}{Leu}{Gly}{Ile}{Ala}{Gly}{Gln}

Sequence Shortening

GPLGIAGQ

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

GPLGIAGQMMPApoptosisMatrix metalloproteinasesPDTphotosensitizerInhibitorinhibitorinhibit

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GPLGIAGQ TFA
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HY-P2213A
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