1. Metabolic Enzyme/Protease
    Apoptosis
  2. MMP
    Apoptosis
  3. GPLGIAGQ

GPLGIAGQ 

Cat. No.: HY-P2213
Handling Instructions

GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT).

For research use only. We do not sell to patients.

Custom Peptide Synthesis

GPLGIAGQ Chemical Structure

GPLGIAGQ Chemical Structure

CAS No. : 109053-09-0

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Description

GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT)[1][2][3].

IC50 & Target

MMP2[1].

In Vitro

GPLGIAGQ is used to trigger PEG deshielding of liposomal carriers, resulting in enhanced cellular internalization[3].

Molecular Weight

711.81

Formula

C₃₁H₅₃N₉O₁₀

CAS No.

109053-09-0

Sequence

Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln

Sequence Shortening

GPLGIAGQ

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

GPLGIAGQMMPApoptosisMatrix metalloproteinasesPDTphotosensitizerInhibitorinhibitorinhibit

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GPLGIAGQ
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