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  2. Antennapedia Peptide TFA

Antennapedia Peptide TFA  (Synonyms: Penetratin peptide TFA)

Cat. No.: HY-P0307A Purity: 98.84%
COA Handling Instructions

Antennapedia Peptide (Penetratin peptide) TFA is a 16 amino acid peptide, originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia and is a member of the family of cell-penetrating peptides.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Antennapedia Peptide TFA Chemical Structure

Antennapedia Peptide TFA Chemical Structure

Size Price Stock Quantity
1 mg USD 84 In-stock
5 mg USD 210 In-stock
10 mg USD 315 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Antennapedia Peptide TFA:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

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Description

Antennapedia Peptide (Penetratin peptide) TFA is a 16 amino acid peptide, originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia and is a member of the family of cell-penetrating peptides.

In Vitro

Antennapedia Peptide TFA is a 16 amino acid peptide (RQIKIWFQNRRMKWKK). The DNA binding domain of the Drosophila transcription factor (Antennapedia), a 60 amino acid protein, is rapidly taken up by cells and has been fused to selected antigens to enhance their immunogenicity. A 16 amino acid peptide Antennapedia Peptide TFA from Antennapedia can facilitate the cytoplasmic uptake of cytotoxic T lymphocyte epitope 9-mer peptides[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

2360.82

Formula

C104H168N34O20S.C2HF3O2

Appearance

Solid

Color

White to off-white

Sequence

Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys

Sequence Shortening

RQIKIWFQNRRMKWKK

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (42.36 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4236 mL 2.1179 mL 4.2358 mL
5 mM 0.0847 mL 0.4236 mL 0.8472 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 50 mg/mL (21.18 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.4236 mL 2.1179 mL 4.2358 mL 10.5895 mL
5 mM 0.0847 mL 0.4236 mL 0.8472 mL 2.1179 mL
10 mM 0.0424 mL 0.2118 mL 0.4236 mL 1.0590 mL
15 mM 0.0282 mL 0.1412 mL 0.2824 mL 0.7060 mL
20 mM 0.0212 mL 0.1059 mL 0.2118 mL 0.5295 mL
25 mM 0.0169 mL 0.0847 mL 0.1694 mL 0.4236 mL
30 mM 0.0141 mL 0.0706 mL 0.1412 mL 0.3530 mL
40 mM 0.0106 mL 0.0529 mL 0.1059 mL 0.2647 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Antennapedia Peptide TFA
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HY-P0307A
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