Arg-Gly-Asp-Ser TFA
Based on 9 publication(s) in Google Scholar
Arg-Gly-Asp-Ser (TFA) is an integrin binding sequence that inhibits integrin receptor function. Arg-Gly-Asp-Ser (TFA) directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1.
For research use only. We do not sell to patients.
- Formula: C17H28F3N7O10
- Molecular Weight:547.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Arg-Gly-Asp-Ser TFA
More- Theranostics. 2020 Oct 26;10(26):12127-12143. [Abstract]
- Adv Sci (Weinh). 2025 Oct 30:e01602. [Abstract]
- Sci Rep. 2021 Jan 25;11(1):2141. [Abstract]
- iScience. 2022 Nov 19;25(12):105642. [Abstract]
- Mol Hum Reprod. 2021 Feb 27;27(3):gaab014. [Abstract]
- J Photochem Photobiol B. 2025 Jul:268:113170. [Abstract]
- J Oral Pathol Med. 2016 Nov;45(10):730-739. [Abstract]
- Res Sq. 2026 Jan 11.
- bioRxiv. 2025 Jun 12.
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Flow Cytometry
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Histological Imaging/Staining
Biological Activity
Chemical Information
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Molecular Weight 547.44
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Formula C17H28F3N7O10
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Synonyms
RGDS peptide TFA; Fibronectin tetrapeptide TFA
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Sequence
Arg-Gly-Asp-Ser
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Sequence Shortening
RGDS
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (9)
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Journal Impact Factor
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Most Recent
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Theranostics
2020 Oct 26;10(26):12127-12143. PMID: 33204333 -
Adv Sci (Weinh)
Cancer Immunotherapy via Disruption of Integrin αvβ3 and CD47 Costabilization on Cancer Cell Surface. [Abstract]2025 Oct 30:e01602. PMID: 41168993
Arg-Gly-Asp-Ser TFA purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Oct 30:e01602. [Abstract]
Flow cytometry analysis of CD47 surface expression on MDA‐MB‐231 cells treated with various concentrations of the integrin αvβ3 inhibitor Arg-Gly-Asp-Ser (RGDS: 0, 1, 2, and 4 µM) for 48 h, including pooled data.
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Sci Rep
2021 Jan 25;11(1):2141. PMID: 33495508 -
iScience
2022 Nov 19;25(12):105642. PMID: 36465134
Arg-Gly-Asp-Ser TFA purchased from MedChemExpress. Usage Cited in: iScience. 2022 Nov 19;25(12):105642. [Abstract]
Representative images of H&E and immunohistochemistry (IHC) staining of Ccm1fl/fl and Ccm1ECKO mice at age P14 treated with vehicle or RGDS peptide (5 mg/kg).
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Mol Hum Reprod
Angiopoietin 2 stimulates trophoblast invasion via a mechanism associated with JNK signaling. [Abstract]2021 Feb 27;27(3):gaab014. PMID: 33629098 -
J Photochem Photobiol B
Binding of collagen I to integrins alleviates UVB-caused mitochondrial disorders in human keratinocytes HaCaT through enhancement of F-actin polymerization. [Abstract]2025 Jul:268:113170. PMID: 40328195 -
J Oral Pathol Med
THBS1 is induced by TGFB1 in the cancer stroma and promotes invasion of oral squamous cell carcinoma. [Abstract]2016 Nov;45(10):730-739. PMID: 26850833 -
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Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)