(E)-Pinocembrin chalcone
(E)-Pinocembrin chalcone is an antibacterial compound that can be isolated from Helichrysum trilineatum.
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- CAS No.: 82451-30-7
- Formule: C15H12O4
- Masse moléculaire:256.25
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
25.4 μM
Compound: 8c
|
Inhibition of human SGLT1 expressed in HEK293 cells assessed as reduction in 2-deoxyglucose uptake pretreated for 10 mins followed by 2-deoxyglucose addition in presence of sodium buffer measured after 1 hr by resazurin dye based fluorescence assay
Inhibition of human SGLT1 expressed in HEK293 cells assessed as reduction in 2-deoxyglucose uptake pretreated for 10 mins followed by 2-deoxyglucose addition in presence of sodium buffer measured after 1 hr by resazurin dye based fluorescence assay
|
[PMID: 28098449] |
| HEK293 | IC50 |
33.3 μM
Compound: 8c
|
Inhibition of human SGLT2 expressed in HEK293 cells assessed as reduction in 2-deoxyglucose uptake pretreated for 10 mins followed by 2-deoxyglucose addition in presence of sodium buffer measured after 1 hr by resazurin dye based fluorescence assay
Inhibition of human SGLT2 expressed in HEK293 cells assessed as reduction in 2-deoxyglucose uptake pretreated for 10 mins followed by 2-deoxyglucose addition in presence of sodium buffer measured after 1 hr by resazurin dye based fluorescence assay
|
[PMID: 28098449] |
| RBL-1 | IC50 |
140 μM
Compound: 3
|
Inhibition of cyclooxygenase in rat RBL1 cells
Inhibition of cyclooxygenase in rat RBL1 cells
|
10.1007/s00044-013-0745-7 |
| RBL-1 | IC50 |
140 μM
Compound: 4
|
In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined
In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determined
|
[PMID: 8254620] |
Chemical Information
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CAS No. 82451-30-7
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Masse moléculaire 256.25
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Formule C15H12O4
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SMILES
O=C(C1=C(C=C(C=C1O)O)O)/C=C/C2=CC=CC=C2
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Synonyms
(E)-2',4',6'-Trihydroxychalcone
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)