2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B1695R
    Methyl nicotinate (Standard) 93-60-7 99.58%
    Methyl nicotinate (Standard) is the analytical standard of Methyl nicotinate. This product is intended for research and analytical applications. Methyl nicotinate (Nicotinic acid methyl ester) is an orally active vasodilator. Methyl nicotinate has analgesic activity. Methyl nicotinate causes local skin erythema when applied topically to the skin. Methyl nicotinate is used as an active ingredient in over-the-counter topical preparations for the study of muscle and joint pain.
    Methyl nicotinate (Standard)
  • HY-B1727R
    Phenanthrene (Standard) 85-01-8 99.57%
    Phenanthrene (Standard) is the analytical standard of Phenanthrene. This product is intended for research and analytical applications. Phenanthrene is an orally active polycyclic aromatic hydrocarbon (PAH) that induces inflammation, oxidative stress, and apoptosis. Additionally, phenanthrene is commonly used to detect or assess PAH pollution in the environment.
    Phenanthrene (Standard)
  • HY-N0149R
    Salicin (Standard) 138-52-3 99.23%
    Salicin (Standard) is the analytical standard of Salicin. This product is intended for research and analytical applications. Salicin is a natural COX inhibitor.
    Salicin (Standard)
  • HY-N0181S
    Ergosterol-d3
    Ergosterol-d3 is the deuterium labeled Ergosterol (HY-N0181). Ergosterol is the primary sterol found in fungi, with antioxidative, anti-proliferative, and anti-inflammatory effects.
    Ergosterol-d3
  • HY-N0278A
    (Rac)-Anemonin 90921-11-2 98.48%
    (Rac)-Anemonin ((Rac)-Pulsatilla camphor) is the diastereoisomer of Anemonin (HY-N0278). Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases.
    (Rac)-Anemonin
  • HY-N0288R
    Lycorine (Standard) 476-28-8 99.54%
    Lycorine (Standard) is the analytical standard of Lycorine. This product is intended for research and analytical applications. Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a Kd value 15.24 nM. Lycorine downregulates the SCAP protein level without changing its transcription. Lycorine is also a melanoma vasculogenic inhibitor. Lycorine can be used for the study of prostate cancer and metabolic diseases.
    Lycorine (Standard)
  • HY-N0318R
    Salvianolic acid A (Standard) 96574-01-5 99.44%
    Salvianolic acid A (Standard) is the analytical standard of Salvianolic acid A. This product is intended for research and analytical applications. Salvianolic acid A could protect the blood brain barrier through matrix metallopeptidase 9 (MMP-9) inhibition and anti-inflammation.
    Salvianolic acid A (Standard)
  • HY-N0570R
    Hydroxytyrosol (Standard) 10597-60-1 99.59%
    Hydroxytyrosol (Standard) (DOPET (Standard)) is the analytical standard of Hydroxytyrosol (HY-N0570). This product is intended for research and analytical applications. Hydroxytyrosol is an orally active, blood-brain barrier-permeable multi-active compound with multiple effects including antibacterial, antioxidant, anti-platelet aggregation, and neuroprotective activities. Hydroxytyrosol not only inhibits the growth of Vibrio by increasing bacterial membrane permeability, but also interacts with DNA and mediates supercoiled DNA relaxation. Meanwhile, Hydroxytyrosol effectively reduces thrombosis and inhibits lipid oxidation by inhibiting COX activity and promoting vascular nitric oxide production. In terms of neuroprotection, Hydroxytyrosol significantly alleviates neuronal apoptosis and inflammatory responses by up-regulating the expression level of ERβ, thereby improving cognitive function in Alzheimer's disease models. Hydroxytyrosol has been widely used in scientific research related to Vibrio infection, arterial thrombosis, Alzheimer's disease and other related fields.
    Hydroxytyrosol (Standard)
  • HY-N0711R
    Carvacrol (Standard) 499-75-2 99.98%
    Carvacrol (Standard) is the analytical standard of Carvacrol. This product is intended for research and analytical applications. Carvacrol is an orally active and blood-brain barrier-permeable monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations.
    Carvacrol (Standard)
  • HY-N10765
    Salvinolone 120278-22-0 98.51%
    Salvinolone is active against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE). Salvinolone shows cytotoxic activity with an IC50 of 47.6 μM against the HL-60 tumor cell line for 72 h.
    Salvinolone
  • HY-N11499
    Myricetin 3-O-α-L-arabinopyranoside 132679-85-7 99.33%
    Myricetin 3-O-α-L-arabinopyranoside is a quercetin derivative and plant flavonoid with antioxidant, antibacterial and antiurease effects. Myricetin 3-O-α-L-arabinopyranoside inhibits A2E photooxidation-induced RPE cell death. Myricetin 3-O-α-L-arabinopyranoside is protective against retinal degeneration and protects against blue light (BL)-induced damage in RPE cells and mouse models.
    Myricetin 3-O-α-L-arabinopyranoside
  • HY-N16129
    Diplacone 73676-38-7 98.38%
    Diplacone is an orally active geranyl flavanone. It is isolated from the fruits of Paulownia tomentosa. Diplacone reduces COX-2 levels and increases the pro-MMP2/MMP2 ratio. It induces ferroptosis-mediated cell death. Diplacone enhances mitochondrial Ca2+ influx and ROS production. It possesses anti-inflammatory and free radical-scavenging activities. Diplacone can be used in research related to ulcerative colitis and non-small cell lung cancer.
    Diplacone
  • HY-N16499
    Hericene A 157207-54-0 99.08%
    Hericene A is an orally active aromatic hericene derivative. Hericene A exhibits anti-inflammatory and neurotrophic activities, and can found in the fruiting bodies of Hericium erinaceus. Hericene A inhibits the secretion of pro-inflammatory mediators. Hericene A promotes axonal growth, neurite branching, neurotrophic factor expression and downstream signal transduction. Hericene A can be used for the research of inflammatory and neurological diseases.
    Hericene A
  • HY-N19254
    Shepherdine 3000-36-0 98%
    Shepherdine, a harmala-type indole and tetrahydro-β-carboline alkaloid, is an antioxidant. Shepherdine scavenges free radicals via single electron transfer from its indole ring, forming an indolyl cation or neutral radical, and may convert to aromatic β-carbolines during this process. Shepherdine can be used for research on antioxidant activity.
    Shepherdine
  • HY-N2065R
    Withaferin A (Standard) 5119-48-2 99.81%
    Withaferin A (Standard) is the analytical standard of Withaferin A. This product is intended for research and analytical applications. Withaferin A is a steroidal lactone isolated from Withania somnifera, inhibits NF-kB activation and targets vimentin, with potent antiinflammatory and anticancer activities. Withaferin A is an inhibitor of endothelial protein C receptor (EPCR) shedding.
    Withaferin A (Standard)
  • HY-N7819S
    Pristane-d40 16416-35-6 98.56%
    Pristane-d40 is the deuterium labeled Pristane. Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil. Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat.
    Pristane-d40
  • HY-P99120
    Anti-Mouse CD11a Antibody (FD441.8)
    Anti-Mouse CD11a Antibody (FD441.8) is an anti-mouse CD11a IgG2b antibody inhibitor derived from the host Rat. Anti-Mouse CD11a Antibody (FD441.8) can neutralize CD11a also known as LFA-1α (lymphocyte function-associated antigen 1 alpha). Anti-Mouse CD11a Antibody (FD441.8) can be used for the researches of inflammation, immunology and cancer, such as transplant and leukemia.
    Anti-Mouse CD11a Antibody (FD441.8)
  • HY-P99131
    Anti-Mouse CD90.2 Antibody (30H12)
    Anti-Mouse CD90.2 Antibody (30H12) is an anti-mouse CD90.2 IgG2b antibody inhibitor derived from host Rat. Anti-Mouse CD90.2 Antibody (30H12) can deplete innate lymphoid cells (ILC) and T cells. Anti-Mouse CD90.2 Antibody (30H12) can be used for the researches of infection, inflammation and immunology, such as Yersinia enterocolitica infection and airway inflammation.
    Anti-Mouse CD90.2 Antibody (30H12)
  • HY-P99754
    Netakimab 1796570-08-5
    Netakimab (BCD-085) is a humanized IgG1κ monoclonal anti-IL-17 antibody that binds to and blocks IL-17 and IL-17A activity, including reduction of downstream IL-6 production. Netakimab can be used for the research of moderate-to-severe plaque psoriasis, ankylosing spondylitis, and COVID-19 with cytokine release syndrome. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
    Netakimab
  • HY-P99983
    Mouse IgG1 (D265A) kappa, Isotype Control 99.52%
    Mouse IgG1 (D265A) kappa, Isotype Control is a mouse IgG1(D265A)κ isotype control with a D265A mutation and inactivity against mouse Fc gamma receptors (FcγR1, FcγR2, FcγR3, FcγR4).
    Mouse IgG1 (D265A) kappa, Isotype Control
Cat. No. Product Name / Synonyms Application Reactivity