Anti-Mouse CD90.2 Antibody (30H12) 

Anti-Mouse CD90.2 Antibody (30H12) is an anti-mouse CD90.2 IgG2b antibody inhibitor derived from host Rat. Anti-Mouse CD90.2 Antibody (30H12) can deplete innate lymphoid cells (ILC) and T cells. Anti-Mouse CD90.2 Antibody (30H12) can be used for the researches of infection, inflammation and immunology, such as Yersinia enterocolitica infection and airway inflammation^[1][2].

Rat IgG2b kappa

Rat IgG2b kappa, Isotype Control

Human/Mouse

Anti-Mouse CD90.2 Antibody (30H12) (100 μg/mouse, i.p., at days -4, -1, 2, 5) depletes innate lymphoid cells (ILC) and reduces survival rate in Rag1^−/− mice with Yersinia enterocolitica infection^[1].
Anti-Mouse CD90.2 Antibody (30H12) (500 μg/mouse, i.p., every other day for 4 times) depletes innate lymphoid 2 cells (ILC2) and reduces airway inflammation and hyperresponsiveness in ozone-induced mice^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

in vivo ILC depletion; in vivo T cell depletion; Western blot

Unconjugated

The product can be reconstituted/diluted with sterile PBS or saline.

150 kDa

Liquid

Colorless to light yellow

[Anti-Mouse CD90.2 Antibody (30H12)]

Please refer to the lot-specific COA for specific buffer information.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Seo GY, et al. LIGHT-HVEM Signaling in Innate Lymphoid Cell Subsets Protects Against Enteric Bacterial Infection. Cell Host Microbe. 2018 Aug 8;24(2):249-260.e4.  [Content Brief]

  [2]. Yang Q, et al. Group 2 innate lymphoid cells mediate ozone-induced airway inflammation and hyperresponsiveness in mice. J Allergy Clin Immunol. 2016 Feb;137(2):571-8.  [Content Brief]