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Netakimab

(Synonyms: BCD-085)
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Based on 1 Customer Validation

Netakimab (BCD-085) is a humanized IgG1κ monoclonal anti-IL-17 antibody that binds to and blocks IL-17 and IL-17A activity, including reduction of downstream IL-6 production. Netakimab can be used for the research of moderate-to-severe plaque psoriasis, ankylosing spondylitis, and COVID-19 with cytokine release syndrome. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).

For research use only. We do not sell to patients.

  • Purity: 95.00%
  • CAS No.: 1796570-08-5
  • Molecular Weight:145.74 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Netakimab
  • Experimental Validation Results for Netakimab
  • Experimental Validation Results for Netakimab
  • Netakimab Chemical Structure
    Netakimab Chemical Structure
CAS No.: 1796570-08-5
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Loaded Netakimab on AHC2 biosensor, can bind IL-17A Protein, Human (HEK293, His, HY-P70527) with an affinity constant of <1.0E-11 M as determined in BLI assay.

  • 1/16

    Flow cytometric analysis of 1X106 Jurkat cells with Netakimab (HY-P99754, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Netakimab Chemical Structure
    1/16
  • Netakimab
  • Loaded Netakimab on AHC2 biosensor, can bind IL-17A Protein, Human (HEK293, His, HY-P70527) with an affinity constant of <1.0E-11 M as determined in BLI assay.
  • Flow cytometric analysis of 1X106 Jurkat cells with Netakimab (HY-P99754, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).